Analysis of genes within the schizophrenia-linked 22q11.2 deletion identifies interaction of night owl/LZTR1 and NF1 in GABAergic sleep control

Cul3 and insomniac are required for rapid ubiquitination of postsynaptic targets and retrograde homeostatic signaling

(2019) Koto Kikuma et al.   Nature Communications

Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination

(2018) M. Steklov et al.   SCIENCE

LZTR1 is a regulator of RAS ubiquitination and signaling

(2018) Johannes W. Bigenzahn et al.   SCIENCE

AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance

(2018) Stanislav Nagy et al.   PLoS Genetics

Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: a study in male mice

(2017) Michael Didriksen et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

GABAergic Mechanisms in Schizophrenia: Linking Postmortem and In Vivo Studies

(2017) Jeroen C. de Jonge et al.   Frontiers in Psychiatry

Obesity in adults with 22q11.2 deletion syndrome

(2016) Sarah L. Voll et al.   GENETICS IN MEDICINE

A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth

(2016) Joseph H.A. Vissers et al.   Nature Communications

Genome-Wide Association Analyses Point to Candidate Genes for Electric Shock Avoidance in Drosophila melanogaster

(2015) Mirjam Appel et al.   PLoS One

Glycogen metabolism and the homeostatic regulation of sleep

(2014) Jean-Marie Petit et al.   METABOLIC BRAIN DISEASE

Mutations in LZTR1 add to the complex heterogeneity of schwannomatosis

(2014) M. J. Smith et al.   NEUROLOGY

GABAB receptors play an essential role in maintaining sleep during the second half of the night in Drosophila melanogaster

(2013) F. Gmeiner et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Lessons From Sleeping Flies: Insights fromDrosophila melanogasteron the Neuronal Circuitry and Importance of Sleep

(2013) Sheetal Potdar et al.   JOURNAL OF NEUROGENETICS

Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas

(2013) Arkadiusz Piotrowski et al.   NATURE GENETICS

Cullin 3 as a novel target in diverse pathologies

(2013) Ana Cristina Andérica-Romero et al.   Redox Biology

CNVs: Harbingers of a Rare Variant Revolution in Psychiatric Genetics

(2012) Dheeraj Malhotra et al.   CELL

Update on Energy Homeostasis and Insufficient Sleep

(2012) Plamen D. Penev   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

CULLIN-3 Controls TIMELESS Oscillations in the Drosophila Circadian Clock

(2012) Brigitte Grima et al.   PLOS BIOLOGY

Cul3 and the BTB Adaptor Insomniac Are Key Regulators of Sleep Homeostasis and a Dopamine Arousal Pathway in Drosophila

(2012) Cory Pfeiffenberger et al.   PLoS Genetics

Evidence for involvement of GNB1L in autism

(2011) Ying-Zhang Chen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

An integrative approach to ortholog prediction for disease-focused and other functional studies

(2011) Yanhui Hu et al.   BMC BIOINFORMATICS

Neurodevelopmental hypothesis of schizophrenia

(2011) Michael J. Owen et al.   BRITISH JOURNAL OF PSYCHIATRY

insomniac and Cullin-3 Regulate Sleep and Wakefulness in Drosophila

(2011) Nicholas Stavropoulos et al.   NEURON

Evidence for association of hyperprolinemia with schizophrenia and a measure of clinical outcome

(2011) Catherine L. Clelland et al.   SCHIZOPHRENIA RESEARCH

Refinement of Tools for Targeted Gene Expression in Drosophila

(2010) B. D. Pfeiffer et al.   GENETICS

pySolo: a complete suite for sleep analysis in Drosophila

(2009) G. F. Gilestro et al.   BIOINFORMATICS

The GABAA Receptor RDL Acts in Peptidergic PDF Neurons to Promote Sleep in Drosophila

(2009) Brian Y. Chung et al.   CURRENT BIOLOGY

A New Positive/Negative Selection Scheme for Precise BAC Recombineering

(2009) Shuwen Wang et al.   MOLECULAR BIOTECHNOLOGY

The genetic and molecular regulation of sleep: from fruit flies to humans

(2009) Chiara Cirelli   NATURE REVIEWS NEUROSCIENCE

Circadian rhythms and sleep in children with autism

(2009) Gena Glickman   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Associations between Sleep Loss and Increased Risk of Obesity and Diabetes

(2008) Kristen L. Knutson et al.   Annals of the New York Academy of Sciences

Sleep Disturbances in Patients with Schizophrenia

(2008) Stefan Cohrs   CNS DRUGS

Large Ventral Lateral Neurons Modulate Arousal and Sleep in Drosophila

(2008) Vasu Sheeba et al.   CURRENT BIOLOGY

Velo-cardio-facial syndrome: 30 Years of study

(2008) Robert J. Shprintzen   Developmental Disabilities Research Reviews

Copy number variations and risk for schizophrenia in 22q11.2 deletion syndrome

(2008) Anne S. Bassett et al.   HUMAN MOLECULAR GENETICS

Large recurrent microdeletions associated with schizophrenia

(2008) Hreinn Stefansson et al.   NATURE

Modulation of GABAA receptor desensitization uncouples sleep onset and maintenance in Drosophila

(2008) Jose Agosto et al.   NATURE NEUROSCIENCE

PDF Cells Are a GABA-Responsive Wake-Promoting Component of the Drosophila Sleep Circuit

(2008) Katherine M. Parisky et al.   NEURON

Neurofibromatosis Type 1 Revisited

(2008) V. C. Williams et al.   PEDIATRICS

Tools for neuroanatomy and neurogenetics in Drosophila

(2008) B. D. Pfeiffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Supportive Evidence for Reduced Expression of GNB1L in Schizophrenia

(2008) Hiroki Ishiguro et al.   SCHIZOPHRENIA BULLETIN