Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress

Title
Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress
Authors
Keywords
prostate cancer, androgen receptor, TP53, RB1, plasticity, antiandrogen, DNA damage, neuroendocrine, PARP, ATR
Journal
Cell Reports
Volume 31, Issue 8, Pages 107669
Publisher
Elsevier BV
Online
2020-05-27
DOI
10.1016/j.celrep.2020.107669

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