Detection of Deleterious On-Target Effects after HDR-Mediated CRISPR Editing

Published 2020 View Full Article

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Title
Detection of Deleterious On-Target Effects after HDR-Mediated CRISPR Editing
Authors
Keywords
CRISPR, induced pluripotent stem cells, iPSCs, homology-directed repair, HDR, on-target effects, genome editing, qPCR, loss-of-heterozygosity, APP
Journal
Cell Reports
Volume 31, Issue 8, Pages 107689
Publisher
Elsevier BV
Online
2020-05-27
DOI
10.1016/j.celrep.2020.107689

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