Development of Tetrachlorophthalimides as Liver X Receptor β (LXRβ)-Selective Agonists

Identification and in Vivo Evaluation of Liver X Receptor β-Selective Agonists for the Potential Treatment of Alzheimer’s Disease

(2016) Shawn J. Stachel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist

(2016) Yajun Zheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Liver X Receptor (LXR) partial agonists: Biaryl pyrazoles and imidazoles displaying a preference for LXRβ

(2015) Ellen Kick et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design and discovery of 2-oxochromene derivatives as liver X receptor β-selective agonists

(2015) Takayuki Matsuda et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and pharmacology of 1,1-bistrifluoromethylcarbinol derivatives as liver X receptor β-selective agonists

(2015) Minoru Koura et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Styrylphenylphthalimides as Novel Transrepression-Selective Liver X Receptor (LXR) Modulators

(2015) Sayaka Nomura et al.   ACS Medicinal Chemistry Letters

The Medicinal Chemistry of Liver X Receptor (LXR) Modulators

(2014) Colin M. Tice et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Biological Evaluation of Novel Transrepression-Selective Liver X Receptor (LXR) Ligands with 5,11-Dihydro-5-methyl-11-methylene-6H-dibenz[b,e]azepin-6-one Skeleton

(2012) Atsushi Aoyama et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of Restriction Enzymes EcoRI, BamHI and HindIII by Phenethylphenylphthalimides Derived from Thalidomide

(2011) Kazunori Motoshima et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Identification of Phenylsulfone-Substituted Quinoxaline (WYE-672) as a Tissue Selective Liver X-receptor (LXR) Agonist

(2010) Baihua Hu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery and SAR of cinnolines/quinolines as liver X receptor (LXR) agonists with binding selectivity for LXRβ

(2009) Baihua Hu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Separation of α-glucosidase-inhibitory and liver X receptor-antagonistic activities of phenethylphenyl phthalimide analogs and generation of LXRα-selective antagonists

(2009) Kazunori Motoshima et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Liver X receptor in cholesterol metabolism

(2009) Chunyan Zhao et al.   JOURNAL OF ENDOCRINOLOGY