In vitro modelling of alveolar repair at the air-liquid interface using alveolar epithelial cells derived from human induced pluripotent stem cells

Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors

(2020) Killian Hurley et al.   Cell Stem Cell

Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells

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In Vitro Induction and In Vivo Engraftment of Lung Bud Tip Progenitor Cells Derived from Human Pluripotent Stem Cells

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Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells

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Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor

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Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics

(2018) Haojia Wu et al.   Cell Stem Cell

Molecular and functional variation in iPSC-derived sensory neurons

(2017) Jeremy Schwartzentruber et al.   NATURE GENETICS

Long-term expansion of alveolar stem cells derived from human iPS cells in organoids

(2017) Yuki Yamamoto et al.   NATURE METHODS

In trans paired nicking triggers seamless genome editing without double-stranded DNA cutting

(2017) Xiaoyu Chen et al.   Nature Communications

Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

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Cigarette Smoke Modulates Repair and Innate Immunity following Injury to Airway Epithelial Cells

(2016) Gimano D. Amatngalim et al.   PLoS One

Alveolar Development and Disease

(2015) Jeffrey A. Whitsett et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Keeping it together: Pulmonary alveoli are maintained by a hierarchy of cellular programs

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Wnt3a Mediates the Inhibitory Effect of Hyperoxia on the Transdifferentiation of AECIIs to AECIs

(2015) Wei Xu et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells

(2015) Sarah X L Huang et al.   Nature Protocols

In vitro generation of human pluripotent stem cell derived lung organoids

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Targeted Correction and Restored Function of the CFTR Gene in Cystic Fibrosis Induced Pluripotent Stem Cells

(2015) Ana M. Crane et al.   Stem Cell Reports

Lung Stem Cell Differentiation in Mice Directed by Endothelial Cells via a BMP4-NFATc1-Thrombospondin-1 Axis

(2014) Joo-Hyeon Lee et al.   CELL

Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function

(2014) Brigid L.M. Hogan et al.   Cell Stem Cell

Lung development: orchestrating the generation and regeneration of a complex organ

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Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells

(2014) Valeria V Orlova et al.   Nature Protocols

Generation of Alveolar Epithelial Spheroids via Isolated Progenitor Cells from Human Pluripotent Stem Cells

(2014) Shimpei Gotoh et al.   Stem Cell Reports

Transdifferentiation of alveolar epithelial type II to type I cells is controlled by opposing TGF-β and BMP signaling

(2013) Lan Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Alveolar epithelial differentiation of human induced pluripotent stem cells in a rotating bioreactor

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Alveolar epithelial cells: Master regulators of lung homeostasis

(2013) Loïc Guillot et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Human iPS cell–derived alveolar epithelium repopulates lung extracellular matrix

(2013) Mahboobe Ghaedi et al.   JOURNAL OF CLINICAL INVESTIGATION

Efficient generation of lung and airway epithelial cells from human pluripotent stem cells

(2013) Sarah X L Huang et al.   NATURE BIOTECHNOLOGY

Endogenous Lung Regeneration

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Virtual nanoscopy: Generation of ultra-large high resolution electron microscopy maps

(2012) Frank G.A. Faas et al.   JOURNAL OF CELL BIOLOGY

Lentiviral Vector Design and Imaging Approaches to Visualize the Early Stages of Cellular Reprogramming

(2011) Eva Warlich et al.   MOLECULAR THERAPY

Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells

(2011) Michael D Green et al.   NATURE BIOTECHNOLOGY

A more efficient method to generate integration-free human iPS cells

(2011) Keisuke Okita et al.   NATURE METHODS

Activation of the WNT/β-Catenin Pathway Attenuates Experimental Emphysema

(2010) Nikolaus Kneidinger et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inflammatory Response and Barrier Properties of a New Alveolar Type 1-Like Cell Line (TT1)

(2009) Ellen H. J. van den Bogaard et al.   PHARMACEUTICAL RESEARCH

Efficient Derivation of Alveolar Type II Cells from Embryonic Stem Cells for In Vivo Application

(2009) Blair Roszell et al.   TISSUE ENGINEERING PART A