Neuroligin-1 is altered in the hippocampus of Alzheimer’s disease patients and mouse models, and modulates the toxicity of amyloid-beta oligomers

Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways

(2019) Xiaoting Wu et al.   NEURON

Bexarotene therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer´s disease

(2019) Jonathan Mauricio Muñoz-Cabrera et al.   PLoS One

Alternative Method to Detect Neuronal Degeneration and Amyloid β Accumulation in Free-Floating Brain Sections With Fluoro-Jade

(2018) Irene L. Gutiérrez et al.   ASN Neuro

The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline

(2018) David Castonguay et al.   CURRENT BIOLOGY

Declining levels of functionally specialized synaptic proteins in plasma neuronal exosomes with progression of Alzheimer’s disease

(2018) Edward J. Goetzl et al.   FASEB JOURNAL

Regulation of the Neuroligin-1 Gene by Clock Transcription Factors

(2018) Lydia Hannou et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Characterization of a 3xTg-AD mouse model of Alzheimer's disease with the senescence accelerated mouse prone 8 (SAMP8) background

(2018) Jessica Virgili et al.   SYNAPSE

Thrombospondin-1 secreted by human umbilical cord blood-derived mesenchymal stem cells rescues neurons from synaptic dysfunction in Alzheimer’s disease model

(2018) Dong Hyun Kim et al.   Scientific Reports

Key mechanisms underlying netrin-1 prevention of impaired spatial and object memory in Aβ1-42 CA1-injected rats

(2018) Elham Zamani et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Genetic Study of Neurexin and Neuroligin Genes in Alzheimer's Disease

(2018) Amalia Martinez-Mir et al.   JOURNAL OF ALZHEIMERS DISEASE

Regulation of hippocampal long term depression by Neuroligin 1

(2018) Rui Dang et al.   NEUROPHARMACOLOGY

Unsupervised excitation: GABAergic dysfunctions in Alzheimer’s disease

(2018) Eleonora Ambrad Giovannetti et al.   BRAIN RESEARCH

Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice

(2017) Jordano Brito-Moreira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptic Adhesion Molecule Pcdh-γC5 Mediates Synaptic Dysfunction in Alzheimer's Disease

(2017) Yanfang Li et al.   JOURNAL OF NEUROSCIENCE

Cell adhesion molecules and sleep

(2017) Emma Kate O’Callaghan et al.   NEUROSCIENCE RESEARCH

Functional significance of rare neuroligin 1 variants found in autism

(2017) Moe Nakanishi et al.   PLoS Genetics

Brain atrophy in Alzheimer’s Disease and aging

(2016) Lorenzo Pini et al.   AGEING RESEARCH REVIEWS

Neurodegeneration in an Animal Model of Chronic Amyloid-beta Oligomer Infusion Is Counteracted by Antibody Treatment Infused with Osmotic Pumps

(2016) Ahmadali Sajadi et al.   Jove-Journal of Visualized Experiments

The soluble extracellular fragment of neuroligin-1 targets Aβ oligomers to the postsynaptic region of excitatory synapses

(2015) Margarita C. Dinamarca et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Age-dependent impairment of glucose tolerance in the 3xTg-AD mouse model of Alzheimer’s disease

(2015) Milene Vandal et al.   FASEB JOURNAL

A truncating mutation in Alzheimer's disease inactivates neuroligin-1 synaptic function

(2015) Enriqueta Tristán-Clavijo et al.   NEUROBIOLOGY OF AGING

Kisspeptin-13 enhances memory and mitigates memory impairment induced by Aβ1–42 in mice novel object and object location recognition tasks

(2015) J.H. Jiang et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Role of Neurexin-1β and Neuroligin-1 in Cognitive Dysfunction After Subarachnoid Hemorrhage in Rats

(2015) Haitao Shen et al.   STROKE

Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 “Signalosome”

(2015) Sylwia Owczarek et al.   NEURAL PLASTICITY

The Effects of Soluble A.β Oligomers on Neurodegeneration in Alzheimer's Disease

(2015) Jonathan Brouillette   CURRENT PHARMACEUTICAL DESIGN

Functional connectivity among spike trains in neural assemblies during rat working memory task

(2014) Jiacun Xie et al.   BEHAVIOURAL BRAIN RESEARCH

Perforant path synaptic loss correlates with cognitive impairment and Alzheimer's disease in the oldest-old

(2014) John L. Robinson et al.   BRAIN

Epigenetic suppression of neuroligin 1 underlies amyloid-induced memory deficiency

(2014) Bihua Bie et al.   NATURE NEUROSCIENCE

What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus

(2014) Anders M. Fjell et al.   PROGRESS IN NEUROBIOLOGY

Neuronal representation of working memory in the medial prefrontal cortex of rats

(2014) Sheng-Tao Yang et al.   Molecular Brain

Regulation of Synaptic nlg-1/Neuroligin Abundance by the skn-1/Nrf Stress Response Pathway Protects against Oxidative Stress

(2014) Trisha A. Staab et al.   PLoS Genetics

The genome-wide landscape of DNA methylation and hydroxymethylation in response to sleep deprivation impacts on synaptic plasticity genes

(2014) R Massart et al.   Translational Psychiatry

A role for the neurexin–neuroligin complex in Alzheimer's disease

(2013) Ikhlas A. Sindi et al.   NEUROBIOLOGY OF AGING

Neuroligin-1 links neuronal activity to sleep-wake regulation

(2013) J. El Helou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurotoxicity and Memory Deficits Induced by Soluble Low-Molecular-Weight Amyloid- 1-42 Oligomers Are Revealed In Vivo by Using a Novel Animal Model

(2012) J. Brouillette et al.   JOURNAL OF NEUROSCIENCE

Transsynaptic Signaling by Activity-Dependent Cleavage of Neuroligin-1

(2012) Rui T. Peixoto et al.   NEURON

Synaptic changes in Alzheimer’s disease and its models

(2012) J. Pozueta et al.   NEUROSCIENCE

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

A standardized and biocompatible preparation of aggregate-free amyloid beta peptide for biophysical and biological studies of Alzheimer's disease

(2011) K. Broersen et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

(2010) Inna Kuperstein et al.   EMBO JOURNAL

Molecular mechanisms of neurodegeneration in Alzheimer's disease

(2010) L. Crews et al.   HUMAN MOLECULAR GENETICS

Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior

(2010) J. Blundell et al.   JOURNAL OF NEUROSCIENCE

Loss of  7 Nicotinic Receptors Enhances  -Amyloid Oligomer Accumulation, Exacerbating Early-Stage Cognitive Decline and Septohippocampal Pathology in a Mouse Model of Alzheimer's Disease

(2010) C. M. Hernandez et al.   JOURNAL OF NEUROSCIENCE

Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

(2009) H. M. Abdul et al.   JOURNAL OF NEUROSCIENCE

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

(2009) Jennifer L. Tomic et al.   NEUROBIOLOGY OF DISEASE

Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model

(2008) Chiho Hirata-Fukae et al.   BRAIN RESEARCH

Network Dynamics Underlying the Formation of Sparse, Informative Representations in the Hippocampus

(2008) M. P. Karlsson et al.   JOURNAL OF NEUROSCIENCE

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model

(2008) Carl Julien et al.   NEUROBIOLOGY OF AGING