Origin of the Regioselective Fatty-Acid Hydroxylation versus Decarboxylation by a Cytochrome P450 Peroxygenase: What Drives the Reaction to Biofuel Production?

A New Class of Enzymes Discovered: A Non-Heme Oxidase Produces Medium-Chain 1-Alkenes

(2015) Robert Kourist   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidative Decarboxylation of Short-Chain Fatty Acids to 1-Alkenes

(2015) Alexander Dennig et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Quantum Mechanics/Molecular Mechanics Modeling of Enzymatic Processes: Caveats and Breakthroughs

(2015) Matthew G. Quesne et al.   CHEMISTRY-A EUROPEAN JOURNAL

Drug Metabolism by Cytochrome P450 Enzymes: What Distinguishes the Pathways Leading to Substrate Hydroxylation Over Desaturation?

(2015) Li Ji et al.   CHEMISTRY-A EUROPEAN JOURNAL

Decarboxylation of Fatty Acids to Terminal Alkenes by Cytochrome P450 Compound I

(2015) Job L. Grant et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydrogen peroxide-independent production of α-alkenes by OleTJE P450 fatty acid decarboxylase

(2014) Yi Liu et al.   Biotechnology for Biofuels

A tutorial for understanding chemical reactivity through the valence bond approach

(2014) Dandamudi Usharani et al.   CHEMICAL SOCIETY REVIEWS

Structure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE(CYP152L1) from theJeotgalicoccussp. 8456 Bacterium

(2014) James Belcher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microbial biosynthesis of medium-chain 1-alkenes by a nonheme iron oxidase

(2014) Zhe Rui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Hydrogen Bonding in Human CYP17 Dictates Hydroxylation versus Lyase Chemistry

(2013) Michael Gregory et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Computational modelling of oxygenation processes in enzymes and biomimetic model complexes

(2013) Sam P. de Visser et al.   CHEMICAL COMMUNICATIONS

Quantum Mechanics/Molecular Mechanics Study on the Oxygen Binding and Substrate Hydroxylation Step in AlkB Repair Enzymes

(2013) Matthew G. Quesne et al.   CHEMISTRY-A EUROPEAN JOURNAL

Does Hydrogen-Bonding Donation to Manganese(IV)-Oxo and Iron(IV)-Oxo Oxidants Affect the Oxygen-Atom Transfer Ability? A Computational Study

(2013) Reza Latifi et al.   CHEMISTRY-A EUROPEAN JOURNAL

De NovoSynthesis of Steroids and Oxysterols in Adipocytes

(2013) Jiehan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent density functional theory model calculations of drug metabolism by cytochrome P450

(2012) Dongmei Li et al.   COORDINATION CHEMISTRY REVIEWS

Compound I Is the Reactive Intermediate in the First Monooxygenation Step during Conversion of Cholesterol to Pregnenolone by Cytochrome P450scc: EPR/ENDOR/Cryoreduction/Annealing Studies

(2012) Roman Davydov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An insect-specific P450 oxidative decarbonylase for cuticular hydrocarbon biosynthesis

(2012) Y. Qiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Terminal Olefin (1-Alkene) Biosynthesis by a Novel P450 Fatty Acid Decarboxylase fromJeotgalicoccusSpecies

(2011) Mathew A. Rude et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Crystal Structure of H2O2-dependent Cytochrome P450SPαwith Its Bound Fatty Acid Substrate

(2011) Takashi Fujishiro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Theoretical Study on the Mechanism of the Oxygen Activation Process in Cysteine Dioxygenase Enzymes

(2011) Devesh Kumar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CYP3A4-Mediated Oxygenation versus Dehydrogenation of Raloxifene

(2010) Chad D. Moore et al.   BIOCHEMISTRY

Cooperative Effects on Radical Recombination in CYP3A4-Catalyzed Oxidation of the Radical Clock β-Thujone

(2009) Yongying Jiang et al.   CHEMBIOCHEM

Hydrocarbon Hydroxylation by Cytochrome P450 Enzymes

(2009) Paul R. Ortiz de Montellano   CHEMICAL REVIEWS

Trends in Substrate Hydroxylation Reactions by Heme and Nonheme Iron(IV)-Oxo Oxidants Give Correlations between Intrinsic Properties of the Oxidant with Barrier Height

(2009) Sam P. de Visser   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Valence Bond Modeling of Trends in Hydrogen Abstraction Barriers and Transition States of Hydroxylation Reactions Catalyzed by Cytochrome P450 Enzymes

(2008) Sason Shaik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY