A Ligand That Targets CUG Trinucleotide Repeats

Naphthyridine-Benzoazaquinolone: Evaluation of a Tricyclic System for the Binding to (CAG)nRepeat DNA and RNA

(2016) Jinxing Li  et al.   Chemistry-An Asian Journal

2-Aminophenanthroline dimer stabilized the C–C mismatched duplex DNA

(2015) Jinxing Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Targeting Toxic RNAs that Cause Myotonic Dystrophy Type 1 (DM1) with a Bisamidinium Inhibitor

(2014) Chun-Ho Wong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploring the Formation and Recognition of an Important G-Quadruplex in a HIF1α Promoter and Its Transcriptional Inhibition by a Benzo[c]phenanthridine Derivative

(2014) Han Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recognition of Chelerythrine to Human Telomeric DNA and RNA G-quadruplexes

(2014) Li-Ping Bai et al.   Scientific Reports

Developing Bivalent Ligands to Target CUG Triplet Repeats, the Causative Agent of Myotonic Dystrophy Type 1

(2013) Amin Haghighat Jahromi et al.   JOURNAL OF MEDICINAL CHEMISTRY

RuCp* Complexes of Ambidentate 4,5-Diazafluorene Derivatives: From Linkage Isomers to Coordination-Driven Self-Assembly

(2013) Vincent T. Annibale et al.   ORGANOMETALLICS

Rational Design of Bioactive, Modularly Assembled Aminoglycosides Targeting the RNA that Causes Myotonic Dystrophy Type 1

(2012) Jessica L. Childs-Disney et al.   ACS Chemical Biology

A small molecule regulates hairpin structures in d(CGG) trinucleotide repeats

(2012) Masaki Hagihara et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

From dynamic combinatorial ‘hit’ to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy

(2012) Leslie O. Ofori et al.   NUCLEIC ACIDS RESEARCH

Small Molecule Modulates Hairpin Structures in CAG Trinucleotide Repeats

(2011) Masaki Hagihara et al.   CHEMBIOCHEM

Molecular therapy in myotonic dystrophy: focus on RNA gain-of-function

(2010) S. A. M. Mulders et al.   HUMAN MOLECULAR GENETICS

AAA−DDD Triple Hydrogen Bond Complexes

(2009) Barry A. Blight et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rational Design of Ligands Targeting Triplet Repeating Transcripts That Cause RNA Dominant Disease: Application to Myotonic Muscular Dystrophy Type 1 and Spinocerebellar Ataxia Type 3

(2009) Alexei Pushechnikov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural insights into CUG repeats containing the ‘stretched U–U wobble’: implications for myotonic dystrophy

(2009) Agnieszka Kiliszek et al.   NUCLEIC ACIDS RESEARCH

A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding

(2009) J. F. Arambula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of RNA-mediated Disease

(2008) Jason R. O'Rourke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Combinatorial Selection of Molecules Capable of Inhibiting the (CUG) Repeat RNA−MBNL1 Interaction In Vitro: Discovery of Lead Compounds Targeting Myotonic Dystrophy (DM1)

(2008) Peter C. Gareiss et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY