nNOS-expressing neurons in the vmPFC transform pPVT-derived chronic pain signals into anxiety behaviors

An amygdalar neural ensemble that encodes the unpleasantness of pain

(2019) Gregory Corder et al.   SCIENCE

Paraventricular Thalamus Projection Neurons Integrate Cortical and Hypothalamic Signals for Cue-Reward Processing

(2019) James M. Otis et al.   NEURON

Hierarchical neural architecture underlying thirst regulation

(2018) Vineet Augustine et al.   NATURE

Dissociation of nNOS from PSD-95 promotes functional recovery after cerebral ischaemia in mice through reducing excessive tonic GABA release from reactive astrocytes

(2017) Yu-Hui Lin et al.   JOURNAL OF PATHOLOGY

Prefrontal cortex output circuits guide reward seeking through divergent cue encoding

(2017) James M. Otis et al.   NATURE

Thalamic Regulation of Sucrose Seeking during Unexpected Reward Omission

(2017) Fabricio H. Do-Monte et al.   NEURON

Epidemiology of pain and relation to psychiatric disorders

(2017) Ana Miriam Velly et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors

(2016) Kun Li et al.   CELL

5-HT2CReceptor Knockdown in the Amygdala Inhibits Neuropathic-Pain-Related Plasticity and Behaviors

(2016) Guangchen Ji et al.   JOURNAL OF NEUROSCIENCE

Synaptic plasticity in the anterior cingulate cortex in acute and chronic pain

(2016) Tim V. P. Bliss et al.   NATURE REVIEWS NEUROSCIENCE

Hippocampal Somatostatin Interneurons Control the Size of Neuronal Memory Ensembles

(2016) Thomas Stefanelli et al.   NEURON

Nitric oxide in the prelimbic medial prefrontal cortex is involved in the anxiogenic-like effect induced by acute restraint stress in rats

(2016) C. Vila-Verde et al.   NEUROSCIENCE

Neural circuits for pain: Recent advances and current views

(2016) C. Peirs et al.   SCIENCE

Neural Mechanisms Underlying Anxiety–Chronic Pain Interactions

(2016) Min Zhuo   TRENDS IN NEUROSCIENCES

(+)-Borneol alleviates mechanical hyperalgesia in models of chronic inflammatory and neuropathic pain in mice

(2015) Jun Jiang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Associations Between Preexisting Mental Disorders and Subsequent Onset of Chronic Headaches: A Worldwide Epidemiologic Perspective

(2015) Ronny Bruffaerts et al.   JOURNAL OF PAIN

The paraventricular thalamus controls a central amygdala fear circuit

(2015) Mario A. Penzo et al.   NATURE

A temporal shift in the circuits mediating retrieval of fear memory

(2015) Fabricio H. Do-Monte et al.   NATURE

Basomedial amygdala mediates top-down control of anxiety and fear

(2015) Avishek Adhikari et al.   NATURE

Neuronal circuits for fear and anxiety

(2015) Philip Tovote et al.   NATURE REVIEWS NEUROSCIENCE

Wakefulness Is Governed by GABA and Histamine Cotransmission

(2015) Xiao Yu et al.   NEURON

Coexistence of Two Forms of LTP in ACC Provides a Synaptic Mechanism for the Interactions between Anxiety and Chronic Pain

(2015) Kohei Koga et al.   NEURON

Placing the paraventricular nucleus of the thalamus within the brain circuits that control behavior

(2015) Gilbert J. Kirouac   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Roles of prefrontal cortex and paraventricular thalamus in affective and mechanical components of visceral nociception

(2015) Angela Jurik et al.   PAIN

Deactivation of excitatory neurons in the prelimbic cortex via Cdk5 promotes pain sensation and anxiety

(2015) Guo-Qiang Wang et al.   Nature Communications

Role of Prelimbic GABAergic Circuits in Sensory and Emotional Aspects of Neuropathic Pain

(2015) Zizhen Zhang et al.   Cell Reports

Antidepressant-like Effects of Cortical Deep Brain Stimulation Coincide With Pro-neuroplastic Adaptations of Serotonin Systems

(2014) Avin Veerakumar et al.   BIOLOGICAL PSYCHIATRY

Interaction of nNOS with PSD-95 Negatively Controls Regenerative Repair after Stroke

(2014) C.-X. Luo et al.   JOURNAL OF NEUROSCIENCE

Activation of the prelimbic medial prefrontal cortex induces anxiety-like behaviors via N-Methyl-D-aspartate receptor-mediated glutamatergic neurotransmission in mice

(2014) Akiyoshi Saitoh et al.   JOURNAL OF NEUROSCIENCE RESEARCH

CAPON-nNOS coupling can serve as a target for developing new anxiolytics

(2014) Li-Juan Zhu et al.   NATURE MEDICINE

The Association of Depression and Anxiety with Pain: A Study from NESDA

(2014) Eric W. de Heer et al.   PLoS One

Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion

(2014) Ghupurjan Gheni et al.   Cell Reports

Increased nitric oxide-mediated neurotransmission in the medial prefrontal cortex is associated with the long lasting anxiogenic-like effect of predator exposure

(2013) Alline Cristina Campos et al.   BEHAVIOURAL BRAIN RESEARCH

The expression of vesicular glutamate transporter 3 and vesicular monoamine transporter 2 induced by brain-derived neurotrophic factor in dorsal root ganglion neurons in vitro

(2013) Dong Liu et al.   BRAIN RESEARCH BULLETIN

Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective

(2013) Dan W. Grupe et al.   NATURE REVIEWS NEUROSCIENCE

Cognitive and emotional control of pain and its disruption in chronic pain

(2013) M. Catherine Bushnell et al.   NATURE REVIEWS NEUROSCIENCE

Synaptic Encoding of Fear Extinction in mPFC-amygdala Circuits

(2013) Jun-Hyeong Cho et al.   NEURON

Enhanced excitability in the infralimbic cortex produces anxiety-like behaviors

(2013) Lin-Lin Bi et al.   NEUROPHARMACOLOGY

Upregulation of presynaptic proteins and protein kinases associated with enhanced glutamate release from axonal terminals (synaptosomes) of the medial prefrontal cortex in rats with neuropathic pain

(2013) Kun-Long Hung et al.   PAIN

S-nitrosylation of AMPA receptor GluA1 regulates phosphorylation, single-channel conductance, and endocytosis

(2013) B. Selvakumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of GABAA receptors in the medial prefrontal cortex produces an anxiolytic-like response

(2012) Jalal Solati et al.   ACTA NEUROPSYCHIATRICA

Thalamic Control of Layer 1 Circuits in Prefrontal Cortex

(2012) S. J. Cruikshank et al.   JOURNAL OF NEUROSCIENCE

Corticostriatal functional connectivity predicts transition to chronic back pain

(2012) Marwan N Baliki et al.   NATURE NEUROSCIENCE

Hippocampal nitric oxide contributes to sex difference in affective behaviors

(2012) Y. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prefrontal dysfunction during emotion regulation in generalized anxiety and panic disorders

(2012) T. Manber Ball et al.   PSYCHOLOGICAL MEDICINE

Neuronal nitric oxide synthase expressing neurons: a journey from birth to neuronal circuits

(2012) Ludovic Tricoire et al.   Frontiers in Neural Circuits

Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders

(2011) B Myers-Schulz et al.   MOLECULAR PSYCHIATRY

Pain and analgesia: The dual effect of nitric oxide in the nociceptive system

(2011) Yara Cury et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Neuronal Nitric Oxide Synthase Alteration Accounts for the Role of 5-HT1A Receptor in Modulating Anxiety-Related Behaviors

(2010) J. Zhang et al.   JOURNAL OF NEUROSCIENCE

BIdirectional Regulation of Neurogenesis by Neuronal Nitric Oxide Synthase Derived from Neurons and Neural Stem Cells

(2010) Chun-Xia Luo et al.   STEM CELLS

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Extinction circuits for fear and addiction overlap in prefrontal cortex

(2009) J. Peters et al.   LEARNING & MEMORY

S-nitrosylation of stargazin regulates surface expression of AMPA-glutamate neurotransmitter receptors

(2009) B. Selvakumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Morphological and functional reorganization of rat medial prefrontal cortex in neuropathic pain

(2009) A. E. Metz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

No NO, no pain? The role of nitric oxide and cGMP in spinal pain processing

(2009) Achim Schmidtko et al.   TRENDS IN NEUROSCIENCES

Presynaptic and Postsynaptic Amplifications of Neuropathic Pain in the Anterior Cingulate Cortex

(2008) H. Xu et al.   JOURNAL OF NEUROSCIENCE

Association of Depression and Anxiety Alone and in Combination With Chronic Musculoskeletal Pain in Primary Care Patients

(2008) Matthew J. Bair et al.   PSYCHOSOMATIC MEDICINE