LncRNA GOLGA2P10 is induced by PERK/ATF4/CHOP signaling and protects tumor cells from ER stress-induced apoptosis by regulating Bcl-2 family members

Cellular functions of long noncoding RNAs

(2019) Run-Wen Yao et al.   NATURE CELL BIOLOGY

Pharmacological targeting of the unfolded protein response for disease intervention

(2019) Claudio Hetz et al.   Nature Chemical Biology

Identification of a TGF-β–miR-195 positive feedback loop in hepatocytes and its deregulation in hepatoma cells

(2018) Ruizhi Wang et al.   FASEB JOURNAL

Liver – master and servant of serum proteome

(2018) Deniz Kuscuoglu et al.   JOURNAL OF HEPATOLOGY

The Unfolded Protein Response and Cell Fate Control

(2018) Claudio Hetz et al.   MOLECULAR CELL

Towards a complete map of the human long non-coding RNA transcriptome

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Integrated Functions of Membrane Property Sensors and a Hidden Side of the Unfolded Protein Response

(2018) Roberto Covino et al.   MOLECULAR CELL

Relieving ER stress to target NASH-driven hepatocellular carcinoma

(2018) Saskia Reibe et al.   Nature Reviews Endocrinology

Long noncoding RNA TSLNC8 is a tumor suppressor that inactivates the interleukin-6/STAT3 signaling pathway

(2017) Jiwei Zhang et al.   HEPATOLOGY

AASLD guidelines for the treatment of hepatocellular carcinoma

(2017) Julie K. Heimbach et al.   HEPATOLOGY

The UPR ER : Sensor and Coordinator of Organismal Homeostasis

(2017) Ashley E. Frakes et al.   MOLECULAR CELL

ER stress and the unfolded protein response in neurodegeneration

(2017) Claudio Hetz et al.   Nature Reviews Neurology

Long Noncoding RNAs in Cancer Pathways

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Protein misfolding in the endoplasmic reticulum as a conduit to human disease

(2016) Miao Wang et al.   NATURE

Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice

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Identification of antisense long noncoding RNAs that function as SINEUPs in human cells

(2016) Aleks Schein et al.   Scientific Reports

The Role of Endoplasmic Reticulum Stress in Human Pathology

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SINEUPs: A new class of natural and synthetic antisense long non-coding RNAs that activate translation

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Targeting the IRE1α–XBP1 branch of the unfolded protein response in human diseases

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New insights into the roles of CHOP-induced apoptosis in ER stress

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ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development

(2014) Hayato Nakagawa et al.   CANCER CELL

Endoplasmic Reticulum Stress in Malignancy

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Hepatitis B virus PreS/S gene variants: Pathobiology and clinical implications

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Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

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Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis

(2013) Wan-Ting Chen et al.   HEPATOLOGY

p58IPK-Mediated Attenuation of the Proapoptotic PERK-CHOP Pathway Allows Malignant Progression upon Low Glucose

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ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

(2013) Jaeseok Han et al.   NATURE CELL BIOLOGY

CCAAT/Enhancer-Binding Protein Homologous (CHOP) Protein Promotes Carcinogenesis in the DEN-Induced Hepatocellular Carcinoma Model

(2013) Viviana Scaiewicz et al.   PLoS One

BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α

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Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat

(2012) Claudia Carrieri et al.   NATURE

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

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Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4-CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA

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Emerging New Roles of GM130, a cis-Golgi Matrix Protein, in Higher Order Cell Functions

(2010) Nobuhiro Nakamura   JOURNAL OF PHARMACOLOGICAL SCIENCES