Histamine H3 Receptor Promotes Cell Survival via Regulating PKA/CREB/CDKN1A Signal Pathway in Hepatocellular Carcinoma

Molecular docking, anti-proliferative activity and induction of apoptosis in human liver cancer cells treated with androstane derivatives: Implication of PI3K/AKT/mTOR pathway

(2020) Shahad W. Kattan et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Upregulated histamine receptor�H3 promotes tumor growth and metastasis in hepatocellular carcinoma

(2019) Deliang Yu et al.   ONCOLOGY REPORTS

Pathophysiological Role of Histamine H4 Receptor in Cancer: Therapeutic Implications

(2019) Melisa B. Nicoud et al.   Frontiers in Pharmacology

Upregulation of histamine receptor H1 promotes tumor progression and contributes to poor prognosis in hepatocellular carcinoma

(2019) Jing Zhao et al.   ONCOGENE

Novel angiotensin receptor blocker, azilsartan induces oxidative stress and NFkB-mediated apoptosis in hepatocellular carcinoma cell line HepG2

(2018) Elham Ahmadian et al.   BIOMEDICINE & PHARMACOTHERAPY

Targeting CREB Pathway Suppresses Small Cell Lung Cancer

(2018) Yifeng Xia et al.   MOLECULAR CANCER RESEARCH

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Tobacco Carcinogen-Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer

(2018) Supriya Srinivasan et al.   CANCER RESEARCH

Inhibition of histamine receptor H3R suppresses prostate cancer growth, invasion and increases apoptosis via the AR pathway

(2018) Jun Chen et al.   Oncology Letters

Androgen deprivation promotes neuroendocrine differentiation and angiogenesis through CREB-EZH2-TSP1 pathway in prostate cancers

(2018) Yan Zhang et al.   Nature Communications

Serum histamine and acetylcholine variations as new noninvasive biochemical markers in staging of experimental hepatocellular carcinoma

(2018) Nabil M. Abdel-Hamid et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Role of tumor microenvironment in tumorigenesis

(2017) Maonan Wang et al.   Journal of Cancer

Histamine H3 receptor antagonist OUP-186 attenuates the proliferation of cultured human breast cancer cell lines

(2016) Satoshi Tanaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The androgen-induced protein AIbZIP facilitates proliferation of prostate cancer cells through downregulation of p21 expression

(2016) Xiang Cui et al.   Scientific Reports

Cimetidine and Clobenpropit Attenuate Inflammation-Associated Colorectal Carcinogenesis in Male ICR Mice

(2016) Takuji Tanaka et al.   Cancers

Inhibition of histamine receptor 3 suppresses glioblastoma tumor growth, invasion, and epithelial-to-mesenchymal transition

(2015) Jia-Ji Lin et al.   Oncotarget

CREB is activated in smooth muscle cells isolated from atherosclerotic plaques and reduces smooth muscle cell proliferation via p21-dependent mechanism

(2014) Lan Sun et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Modulation of behavior by the histaminergic system: Lessons from HDC-, H3R- and H4R-deficient mice

(2014) Erich H. Schneider et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Roles of histamine on the expression of aldehyde dehydrogenase 1 in endometrioid adenocarcinoma cell line

(2014) Yi Wang et al.   Cancer Medicine

p21-Activated kinase 4 promotes prostate cancer progression through CREB

(2012) M-H Park et al.   ONCOGENE

The H4 histamine receptor agonist, clobenpropit, suppresses human cholangiocarcinoma progression by disruption of epithelial mesenchymal transition and tumor metastasis

(2011) Fanyin Meng et al.   HEPATOLOGY

Histamine deficiency promotes inflammation-associated carcinogenesis through reduced myeloid maturation and accumulation of CD11b+Ly6G+ immature myeloid cells

(2010) Xiang Dong Yang et al.   NATURE MEDICINE

H3 Histamine Receptor-Mediated Activation of Protein Kinase C  Inhibits the Growth of Cholangiocarcinoma In vitro and In vivo

(2009) H. Francis et al.   MOLECULAR CANCER RESEARCH

Histamine regulates pancreatic carcinoma cell growth through H3 and H4 receptors

(2008) G. P. Cricco et al.   INFLAMMATION RESEARCH

Autoregulation of McA-RH7777 Hepatoma Cell Proliferation by Histamine H3 Receptors

(2008) E. Davenas et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells

(2008) Jillian G Baker   BMC Pharmacology & Toxicology