Article
Multidisciplinary Sciences
Rayid Abdulqawi, Rana Ahmed Saleh, Edward Devol, Haifa Aldakhil, Waleed Saleh, Mahmoud Hashim, Eid Albogumi, Ghada Algwaiz, Mohammed Khalid, Eid Abdullah Al-Mutairy
Summary: This study aimed to describe the survival outcomes of underweight patients who underwent lung transplantation. The study found that underweight patients had similar hospital and intensive care unit stays compared to other patients, and there was no significant difference in mortality risk between underweight patients and patients with normal BMIs. Therefore, patients with BMIs of 13-17 kg/m(2) may be candidates for lung transplantation.
Article
Biochemistry & Molecular Biology
Eleonora Faccioli, Vincenzo Verzeletti, Chiara Giraudo, Marco Schiavon, Fiorella Calabrese, Monica Loy, Federico Rea, Andrea Dell'Amore
Summary: Pleuroparenchymal fibroelastosis (PPFE) is a rare condition characterized by fibrosis involving the pleura and the upper lobes. Lung transplantation (LT) is the treatment of choice for end-stage PPFE. This study reports the experience of a single center and compares it with existing evidence on the topic of LT for PPFE.
Article
Respiratory System
Manuel L. Ribeiro Neto, Andrea Valeria Arrossi, Ruchi Yadav, Daniel A. Culver, Sanjay Mukhopadhyay, Joseph G. Parambil, Brian D. Southern, Leslie Tolle, Aman Pande, Francisco A. Almeida, Debasis Sahoo, Jessica Glennie, Usman Ahmad, Atul C. Mehta, Thomas R. Gildea
Summary: Transbronchial cryobiopsy is an effective diagnostic method for interstitial lung diseases, with an increasing diagnostic yield over time. However, it is associated with a risk of grade 4 bleeding at a rate of 11.8%.
BMC PULMONARY MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Matthew Zheng, Ibraheem Yousef, Albert J. Mamary, Huaqing Zhao, James McEldrew, Adam Adika, Norihisa Shigemura, Francis Cordova, Gerald J. Criner, Patrick Mulhall, Jonathan Galli, Kartik Shenoy, James Brown, Nathanial Marchetti, Parth Rali, Sameep Sehgal
Summary: This study reviewed the incidence of VTE post lung transplantation and identified risk factors such as the use of cardiopulmonary bypass (CPB) and interruption of VTE prophylaxis. Measures to ensure consistent and uninterrupted prophylaxis may help decrease VTE incidence after lung transplantation.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2021)
Article
Immunology
Jassin Rashidi-Alavijeh, Alexandra Frey, Moritz Passenberg, Johannes Korth, Jaqueline Zmudzinski, Olympia E. Anastasiou, Fuat H. Saner, Michael Jahn, Christian M. Lange, Katharina Willuweit
Summary: SARS-CoV-2 vaccine BNT162b2 showed lower immunogenicity in liver transplant recipients compared to the control group, especially among patients receiving mycophenolate mofetil.
Article
Pediatrics
Jordan Sill, Shankar Baskar, Huaiyu Zang, David Spar, Ilias Iliopoulos, David L. S. Morales, Don Hayes Jr, Wonshill Koh
Summary: This study retrospectively analyzed lung transplant recipients at a pediatric center from 2014 to 2022 and found that three out of nineteen recipients (15%) developed atrial arrhythmia. The occurrence of atrial arrhythmia occurred 9-10 days after lung transplantation, and only recipients older than 12 years old experienced this complication. Atrial arrhythmia did not affect hospital stay duration or short-term mortality. All recipients with atrial arrhythmia were discharged on medication, which was discontinued at 6 months for those without recurrence.
FRONTIERS IN PEDIATRICS
(2023)
Article
Surgery
R. van Pel, C. T. Gan, W. van der Bij, E. A. M. Verschuuren, J. P. A. van Gemert, C. van de Wauwer, M. E. Erasmus, D. J. Slebos
Summary: Post lung transplantation airway complications, especially stenosis, significantly affect survival. Risk factors for the development of airway complications are unclear.
TRANSPLANT INTERNATIONAL
(2023)
Article
Immunology
Youngmok Park, Nam Eun Kim, Se Hyun Kwak, Moo Suk Park, Su Jin Jeong, Jin Gu Lee, Hyo Chae Paik, Song Yee Kim, Young Ae Kang
Summary: This study aimed to evaluate the epidemiology of NTM infection after lung transplantation in South Korea. A retrospective analysis of 215 lung transplant recipients revealed that 14 patients (6.5%) were diagnosed with NTM infection.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2022)
Article
Medicine, General & Internal
Ko-Wei Chang, Hsin-Yueh Fang
Summary: This retrospective study analyzed bronchoscopy findings and clinical outcomes during percutaneous dilation tracheostomy (PDT). Unexpected endotracheal or endobronchial masses were discovered in a significant proportion of patients with chronic respiratory failure during PDT, and a high rate of weaning failure was noted in these patients. Completing bronchoscopy during PDT may offer additional clinical benefits.
Article
Pediatrics
Maria Lasa-Lazaro, Esther Ramos-Boluda, Esther Mancebo, Maria Jose Castro-Panete, Rocio Gonzalez-Sacristan, Javier Serradilla, Ane Miren Andres-Moreno, Francisco Hernandez-Oliveros, Estela Paz-Artal, Paloma Talayero
Summary: This study demonstrates the effectiveness of antibody-removal therapies (ART) in pediatric intestinal and multivisceral transplants with de novo donor-specific anti-HLA antibodies (dnDSA). ART was successful in removing DSA and preventing rejection even in the absence of clinical symptoms.
FRONTIERS IN PEDIATRICS
(2023)
Article
Medicine, General & Internal
Limin Ding, Xizhi Yu, Rui Zhang, Junjie Qian, Wu Zhang, Qinchuan Wu, Lin Zhou, Zhe Yang, Shusen Zheng
Summary: This study retrospectively analyzed the clinical data of 22 recipients who underwent full-right full-left liver transplantation. The transplantation was successful and the recipients had good postoperative outcomes in terms of complications and prognosis.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Immunology
Alexander Nikoloudis, Ines Julia Neumann, Veronika Buxhofer-Ausch, Sigrid Machherndl-Spandl, Michaela Binder, Emine Kaynak, Robert Milanov, Stefanie Nocker, Olga Stiefel, Irene Strassl, Dagmar Wipplinger, Margarete Moyses, Heidrun Kerschner, Petra Apfalter, Michael Girschikofsky, Andreas Petzer, Ansgar Weltermann, Johannes Clausen
Summary: This retrospective study assessed the humoral response to mRNA vaccines in 167 HSCT recipients and identified factors affecting non-response. The study found that vaccination as early as 3 months post-HSCT showed promising results, with a majority achieving seroconversion after receiving up to four doses. Factors such as low B cell counts and ongoing immunosuppression with mycophenolate mofetil (MMF) hindered the vaccine response.
Article
Medicine, General & Internal
Carolin Steinack, Helene Balmer, Silvia Ulrich, Thomas Gaisl, Daniel P. Franzen
Summary: This pilot study evaluated the risks and feasibility of using one-lung ventilation (OLV) through a single-lumen endotracheal tube (SLT) during rigid bronchoscopy (RB) in patients with malignant airway stenosis. The study found that OLV using an SLT during RB could be a new treatment approach for endobronchial ablative procedures without increasing bronchoscopy-associated risks, allowing concurrent high-energy treatments.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Immunology
Scott C. Roberts, Ankit Bharat, Chitaru Kurihara, Rade Tomic, Michael G. Ison
Summary: Donor-derived Ureaplasma spp in lung transplant was associated with fatal hyperammonemia syndrome. Recipients of organs with Ureaplasma spp who received empiric therapy did not develop hyperammonemia syndrome. Screening lung donors for Ureaplasma spp might allow for targeted therapy to reduce risk for development of hyperammonemia syndrome.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Microbiology
Eun-Young Kim, Seung-Hyun Yong, Min-Dong Sung, A-La Woo, Young-Mok Park, Ha-Eun Kim, Su-Jin Jung, Song-Yee Kim, Jin-Gu Lee, Young-Sam Kim, Hyo-Chae Paik, Moo-Suk Park
Summary: The potential of Aspergillus galactomannan antigen titer (AGT) in serum and bronchoalveolar lavage fluid (BALF) and serum titers of beta-D-glucan (BDG) in predicting invasive pulmonary aspergillosis (IPA) were investigated in lung transplantation recipients. The cutoff values for AGT were found to be 0.560 in serum and 0.600 in BALF, with sensitivities and specificities ranging from 50% to 85%, and AUCs ranging from 0.724 to 0.895. A lower cutoff value of 1.0 was suggested when IPA was highly suspicious. Serum and BALF AGT showed a correlation with a history of diabetes mellitus.
