Journal
TRAFFIC
Volume 21, Issue 6, Pages 404-418Publisher
WILEY
DOI: 10.1111/tra.12730
Keywords
RNA binding protein; RNA cis-element; RNA localization; RNA transport; zipcode
Categories
Funding
- NIGMS NIH HHS [R35 GM133385, T32 GM008497] Funding Source: Medline
Ask authors/readers for more resources
Essentially all cells contain a variety of spatially restricted regions that are important for carrying out specialized functions. Often, these regions contain specialized transcriptomes that facilitate these functions by providing transcripts for localized translation. These transcripts play a functional role in maintaining cell physiology by enabling a quick response to changes in the cellular environment. Here, we review how RNA molecules are trafficked within cells, with a focus on the subcellular locations to which they are trafficked, mechanisms that regulate their transport and clinical disorders associated with misregulation of the process.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available