Late Protective Effect of Netrin-1 in the Murine Acetaminophen Hepatotoxicity Model

Novel Therapeutic Approaches Against Acetaminophen-induced Liver Injury and Acute Liver Failure

(2020) Hartmut Jaeschke et al.   TOXICOLOGICAL SCIENCES

Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair

(2019) Wenting Yang et al.   Nature Communications

Delayed Treatment with 4-Methylpyrazole Protects against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun N-Terminal Kinase

(2019) Jephte Y Akakpo et al.   TOXICOLOGICAL SCIENCES

Acetaminophen Hepatotoxicity

(2019) Anup Ramachandran et al.   SEMINARS IN LIVER DISEASE

The Effect of Netrin-1 on Neutrophil and Breast Cancer Cell Migration and their Migratory Interaction

(2018) Jolly Hipoilito et al.   BIOPHYSICAL JOURNAL

4-Methylpyrazole protects against acetaminophen hepatotoxicity in mice and in primary human hepatocytes

(2018) JY Akakpo et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Netrin-1 promotes diabetic corneal wound healing through molecular mechanisms mediated via the adenosine 2B receptor

(2018) Yangyang Zhang et al.   Scientific Reports

Revisiting Netrin-1: One Who Guides (Axons)

(2018) Nicholas P. Boyer et al.   Frontiers in Cellular Neuroscience

Kupffer Cell Transplantation in Mice for Elucidating Monocyte/Macrophage Biology and for Potential in Cell or Gene Therapy

(2016) Simone Merlin et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity

(2016) Kuo Du et al.   ARCHIVES OF TOXICOLOGY

The neuroimmune guidance cue netrin-1 controls resolution programs and promotes liver regeneration

(2016) Martin Schlegel et al.   HEPATOLOGY

Bone-protective Functions of Netrin 1 Protein

(2016) Kenta Maruyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Netrin-1 attenuates the progression of renal dysfunction by blocking endothelial-to-mesenchymal transition in the 5/6 nephrectomy rat model

(2016) Jiuxu Bai et al.   BMC Nephrology

Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes

(2015) Yuchao Xie et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Guidance Cue Netrin-1 and the Regulation of Inflammation in Acute and Chronic Kidney Disease

(2014) Punithavathi Ranganathan et al.   MEDIATORS OF INFLAMMATION

Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity

(2014) Bhama Ramkhelawon et al.   NATURE MEDICINE

Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans

(2014) C. David Williams et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Role of hepatic resident and infiltrating macrophages in liver repair after acute injury

(2013) Qiang You et al.   BIOCHEMICAL PHARMACOLOGY

Combining chemotherapeutic agents and netrin-1 interference potentiates cancer cell death

(2013) Andrea Paradisi et al.   EMBO Molecular Medicine

Netrin-1 Attenuates Cardiac Ischemia Reperfusion Injury and Generates Alternatively Activated Macrophages

(2013) Xiaogang Mao et al.   INFLAMMATION

Regulation of Neutrophil Function by Adenosine

(2012) Kathryn E. Barletta et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity

(2012) Hartmut Jaeschke et al.   DRUG METABOLISM REVIEWS

Source and characterization of hepatic macrophages in acetaminophen-induced acute liver failure in humans

(2012) Charalambos Gustav Antoniades et al.   HEPATOLOGY

Increased Serum Enzyme Levels Associated with Kupffer Cell Reduction with No Signs of Hepatic or Skeletal Muscle Injury

(2011) Zaher A. Radi et al.   AMERICAN JOURNAL OF PATHOLOGY

Adenosine promotes alternative macrophage activation via A2A and A2B receptors

(2011) Balázs Csóka et al.   FASEB JOURNAL

Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity

(2011) Hartmut Jaeschke et al.   LIVER INTERNATIONAL

Netrin-1 Dampens Pulmonary Inflammation during Acute Lung Injury

(2010) Valbona Mirakaj et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Netrin-1 Signaling Dampens Inflammatory Peritonitis

(2010) V. Mirakaj et al.   JOURNAL OF IMMUNOLOGY

Acetaminophen-induced hepatic neutrophil accumulation and inflammatory liver injury in CD18-deficient mice

(2010) Clarence David Williams et al.   LIVER INTERNATIONAL

Novel mechanisms of protection against acetaminophen hepatotoxicity in mice by glutathione and N-acetylcysteine

(2009) Chieko Saito et al.   HEPATOLOGY

Hypoxia-inducible factor–dependent induction of netrin-1 dampens inflammation caused by hypoxia

(2009) Peter Rosenberger et al.   NATURE IMMUNOLOGY

Role of JNK Translocation to Mitochondria Leading to Inhibition of Mitochondria Bioenergetics in Acetaminophen-induced Liver Injury

(2008) Naoko Hanawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury

(2008) Michael P. Holt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer

(2008) J. Fitamant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA