Journal
TALANTA
Volume 211, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.talanta.2019.120660
Keywords
BPQDs; NiFe2O4 NTs; Dual-mode immunosensor; ECL immunosensor; Photothermal immunosensor; LSR
Categories
Funding
- NSFC [21877012, 21575024]
- National Science Foundation of Fujian Province [2016J06003, 2019J01052063, 2017J01620]
- Education Department of Fujian Province [JK2016009, FBJG20170186, JA14071]
Ask authors/readers for more resources
An electrochemiluminescence and photothermal immunosensor based on a dual-modality integrated probe was proposed for sensitive and reliable detection of lipolysis stimulated lipoprotein receptor (LSR), a new biomarker of ovarian cancer. Black phosphorous quantum dots (BPQDs) possess fascinating electrochemical property and unique photothermal effect, which could not only enhance ECL signal of N-(4-aminobutyl)-N-ethylisoluminol (ABED through accelerating dissolved O-2 evolution but also realize temperature signal output by converting laser energy into heat. Furthermore, NiFe2O4 nanotubes (NiFe2O4 NTs) have large specific surface area and favorable adsorption ability, which could increase the immobilized amount of ABEI and BPQDs, further strengthening ECL and temperature signal. As a result, a dual-mode immunosensor was constructed and realized ECL and temperature dual signal to detect LSR, making the results more reliable. This work provided a new thought for the development of sensitive and accurate sensors and was expected to employ for determination of other biomarkers.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available