Individual participant data meta‐analysis to examine interactions between treatment effect and participant‐level covariates: Statistical recommendations for conduct and planning

A new justification of the Hartung‐Knapp method for random‐effects meta‐analysis based on weighted least squares regression

(2019) Robbie C.M. Aert et al.   Research Synthesis Methods

Statistical approaches to identify subgroups in meta-analysis of individual participant data: a simulation study

(2019) Michail Belias et al.   BMC Medical Research Methodology

Models with interactions overestimated heterogeneity of treatment effects and were prone to treatment mistargeting

(2019) David van Klaveren et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Simulation-based power calculations for planning a two-stage individual participant data meta-analysis

(2018) Joie Ensor et al.   BMC Medical Research Methodology

A recursive partitioning approach for subgroup identification in individual patient data meta-analysis

(2018) Dipesh Mistry et al.   STATISTICS IN MEDICINE

Individual participant data meta-analysis of continuous outcomes: A comparison of approaches for specifying and estimating one-stage models

(2018) Amardeep Legha et al.   STATISTICS IN MEDICINE

How often can meta-analyses of individual-level data individualize treatment? A meta-epidemiologic study

(2018) Ewoud Schuit et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Statistical pitfalls of personalized medicine

(2018) Stephen Senn   NATURE

Meta-analysis of non-linear exposure-outcome relationships using individual participant data: A comparison of two methods

(2018) Ian R. White et al.   STATISTICS IN MEDICINE

Personalized evidence based medicine: predictive approaches to heterogeneous treatment effects

(2018) David M Kent et al.   BMJ-British Medical Journal

One-stage random effects meta-analysis using linear mixed models for aggregate continuous outcome data

(2018) Katerina Papadimitropoulou et al.   Research Synthesis Methods

Meta-analytical methods to identify who benefits most from treatments: daft, deluded, or deft approach?

(2017) David J Fisher et al.   BMJ-British Medical Journal

Multivariate and network meta-analysis of multiple outcomes and multiple treatments: rationale, concepts, and examples

(2017) Richard D Riley et al.   BMJ-British Medical Journal

Meta-analytical methods to identify who benefits most from treatments: daft, deluded, or deft approach?

(2017) David J Fisher et al.   BMJ-British Medical Journal

Multivariate and network meta-analysis of multiple outcomes and multiple treatments: rationale, concepts, and examples

(2017) Richard D Riley et al.   BMJ-British Medical Journal

One-stage individual participant data meta-analysis models: estimation of treatment-covariate interactions must avoid ecological bias by separating out within-trial and across-trial information

(2016) Hairui Hua et al.   STATISTICS IN MEDICINE

Meta-analysis using individual participant data: one-stage and two-stage approaches, and why they may differ

(2016) Danielle L. Burke et al.   STATISTICS IN MEDICINE

Tutorial in biostatistics: data-driven subgroup identification and analysis in clinical trials

(2016) Ilya Lipkovich et al.   STATISTICS IN MEDICINE

Multivariable fractional polynomial interaction to investigate continuous effect modifiers in a meta-analysis on higher versus lower PEEP for patients with ARDS

(2016) Benjamin Kasenda et al.   BMJ Open

Confounding, effect modification, and the odds ratio: common misinterpretations

(2015) Ian Shrier et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Mastering variation: variance components and personalised medicine

(2015) Stephen Senn   STATISTICS IN MEDICINE

Individual Participant Data (IPD) Meta-analyses of Randomised Controlled Trials: Guidance on Their Use

(2015) Jayne F. Tierney et al.   PLOS MEDICINE

Individual Participant Data (IPD) Meta-analyses of Diagnostic and Prognostic Modeling Studies: Guidance on Their Use

(2015) Thomas P. A. Debray et al.   PLOS MEDICINE

Multilevel mixed effects parametric survival models using adaptive Gauss-Hermite quadrature with application to recurrent events and individual participant data meta-analysis

(2014) Michael J. Crowther et al.   STATISTICS IN MEDICINE

Stratified medicine in European Medicines Agency licensing: a systematic review of predictive biomarkers

(2014) Kinga Malottki et al.   BMJ Open

Multivariate meta-analysis using individual participant data

(2014) R. D. Riley et al.   Research Synthesis Methods

Interpretation of Subgroup Analyses in Randomized Trials: Heterogeneity Versus Secondary Interventions

(2013) Tyler J. VanderWeele et al.   ANNALS OF INTERNAL MEDICINE

Individual Participant Data Meta-Analysis for a Binary Outcome: One-Stage or Two-Stage?

(2013) Thomas P. A. Debray et al.   PLoS One

Prognosis research strategy (PROGRESS) 4: Stratified medicine research

(2013) A. D. Hingorani et al.   BMJ-British Medical Journal

Using aggregate data to estimate the standard error of a treatment-covariate interaction in an individual patient data meta-analysis

(2012) Stephanie A. Kovalchik et al.   BIOMETRICAL JOURNAL

Statistical Analysis of Individual Participant Data Meta-Analyses: A Comparison of Methods and Recommendations for Practice

(2012) Gavin B. Stewart et al.   PLoS One

Sample size and power calculations for medical studies by simulation when closed form expressions are not available

(2012) Sabine Landau et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Multivariate meta-analysis for non-linear and other multi-parameter associations

(2012) A. Gasparrini et al.   STATISTICS IN MEDICINE

Simulation methods to estimate design power: an overview for applied research

(2011) Benjamin F Arnold et al.   BMC Medical Research Methodology

A critical review of methods for the assessment of patient-level interactions in individual participant data meta-analysis of randomized trials, and guidance for practitioners

(2011) D.J. Fisher et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Rejoinder to commentaries on ‘Multivariate meta-analysis: Potential and promise’

(2011) Dan Jackson et al.   STATISTICS IN MEDICINE

A new strategy for meta-analysis of continuous covariates in observational studies

(2011) Willi Sauerbrei et al.   STATISTICS IN MEDICINE

Random effects meta-analysis of event outcome in the framework of the generalized linear mixed model with applications in sparse data

(2010) Theo Stijnen et al.   STATISTICS IN MEDICINE

Meta-analysis of a binary outcome using individual participant data and aggregate data

(2010) Richard D. Riley et al.   Research Synthesis Methods

Empirical comparison of subgroup effects in conventional and individual patient data meta-analyses

(2008) Laura Koopman et al.   INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE

Interactions Between Treatment and Continuous Covariates: A Step Toward Individualizing Therapy

(2008) Patrick Royston et al.   JOURNAL OF CLINICAL ONCOLOGY

A re-evaluation of random-effects meta-analysis

(2008) Julian P. T. Higgins et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY

Meta-analysis of continuous outcomes combining individual patient data and aggregate data

(2007) Richard D. Riley et al.   STATISTICS IN MEDICINE