Article
Horticulture
Venelina Popova, Nadezhda Mazova, Tanya Ivanova, Nadezhda Petkova, Magdalena Stoyanova, Albena Stoyanova, Sezai Ercisli, Amine Assouguem, Mohammed Kara, Samar Zuhair Alshawwa, Omkulthom Al Kamaly
Summary: This study determined the presence of certain nutrients and bioactive substances in Physalis alkekengi fruit from Bulgaria, and revealed differences between different phenotypes. The fruit was found to be rich in extractable phenolics and exhibited good antioxidant activity. These findings support the potential phytonutritive value of P. alkekengi fruit and suggest further research opportunities.
Article
Medicine, Research & Experimental
Mengru Yang, Mantong Zhao, Tianyi Xia, Ying Chen, Wei Li, Han Zhang, Mingming Peng, Chuanqiu Li, Xia Cao, Lanyuan Liang, Yimin Yue, Luyang Zhong, Jieyong Du, Jianhua Li, Yi Wang, Zunpeng Shu
Summary: In this study, the pharmacological effects and molecular mechanisms of Physalis alkekengi L. var. franchetii (PAF) in the treatment of atopic dermatitis (AD) were determined. The results showed that PAF gel (PAFG) and PAFG+MF (mometasone furoate) reduced AD severity and inhibited inflammatory responses in the skin. PAFG also alleviated the side effects caused by MF.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Chemistry, Applied
Jia-Min Sun, Ji-Xiang He, Min Huang, Hui-Xin Hu, Lin-Tao Xu, Kai-Li Fang, Xiao-Ning Wang, Tao Shen
Summary: Two new physalins, 7 alpha-hydroxy-5-deoxy-4-dehydrophysalin IX (1) and 5-deoxy-4-dehydrophysalin IX (2), were isolated from Physalis alkekengi L. var. franchetii (Mast.) Makino, along with six known compounds. Compound 1 showed weak NAD(P)H: quinone reductase inducing activity, and compounds 5 and 6 were isolated from the genus Physalis for the first time in this study.
NATURAL PRODUCT RESEARCH
(2022)
Article
Chemistry, Applied
Jian-Lu Sun, Yong-Jun Jiang, Lin Cheng
Summary: Two new physalin derivatives were isolated from Physalis alkekengi. Compound 1 exhibited moderate cytotoxicity against PC-3 cancer cells, while compound 2 showed no cytotoxicity.
NATURAL PRODUCT RESEARCH
(2021)
Article
Chemistry, Medicinal
Cui Fang Wang, Wen Juan Xu, Ying Xu, Yi Xuan Wang, Jie Qing Liu
Summary: The fruits of Physalis alkekengi L. var. franchetii in China contain various compounds, among which Physapubescin M shows significant anti-inflammatory effects on macrophages, reducing the expression of inflammatory proteins and cytokines in a dose-dependent manner. Transcriptomic analyses reveal the potential mechanism of withanolides in inhibiting inflammation, providing a theoretical basis for the use of Physalis fruits.
PHYTOTHERAPY RESEARCH
(2021)
Article
Chemistry, Applied
Zunpeng Shu, Yun Tang, Yanni Yang, Zihe Ding, Renxing Zhong, Tianyi Xia, Xinjia Li, Cuiying Zheng, Zhixiong Wen, Wei Li, Yi Wang
Summary: Two new hexenol glycosides were isolated from the fruit of Physalis alkekengi var. franchetii, and their structures were determined through detailed spectroscopic analysis. This is the first report of (Z) and (E) 3-hexenol glycosides from this plant species.
NATURAL PRODUCT RESEARCH
(2021)
Article
Plant Sciences
Liyuan Qu, Chunli Gan, Xiaoling Cheng, Congcong Lin, Yanli Wang, Libo Wang, Jian Huang, Jinhui Wang
Summary: This study mined the biosynthetic and structure modification-related genes of physalins through transcriptomic and metabolomic profiling. The results provide valuable information on the physalin metabolites and the enzymes involved in their biosynthetic pathways. Additionally, potential biomarkers for quality control of P. alkekengi in herb industry were identified.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Venelina Popova, Zhana Petkova, Nadezhda Mazova, Tanya Ivanova, Nadezhda Petkova, Magdalena Stoyanova, Albena Stoyanova, Sezai Ercisli, Zuhal Okcu, Sona Skrovankova, Jiri Mlcek
Summary: The study found that all parts of the bladder cherry are rich in oil, nutrients, and bioactive compounds, making them potential sources for human and animal nutrition as well as perfumery and cosmetics.
Article
Chemistry, Medicinal
Xue-Yi Wu, Tian Wang, Hui-Xin Hu, Kan Zhang, Yu Zhao, Bao-Bing Zhao, Hong-Xiang Lou, Xiao-Ning Wang, Tao Shen
Summary: Rhamnazin (RN) is a flavonol compound extracted from Physalis alkekengi L. var. franchetii, which has been used in traditional Chinese medicine for treating pulmonary diseases. This study reveals that RN activates the Nrf2 pathway and effectively alleviates oxidative stress and inflammation in pulmonary disorders. The therapeutic effects of RN are associated with inhibition of NF-κB and promotion of cell autophagy.
PHYTOTHERAPY RESEARCH
(2022)
Article
Biotechnology & Applied Microbiology
Bolun Zhang, Yiping Jin, Jiaxu Qi, Huan Chen, Guang Chen, Shanshan Tang
Summary: PCPH, a porous carbon material prepared from Physalis alkekengi L. husk (PH), exhibited excellent surface properties with a high specific surface area and total pore volume. The adsorption performance of PCPH, especially towards Malachite Green, was studied, showing high adsorption capacity and potential application in environmental water pollution treatment.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2021)
Review
Biochemistry & Molecular Biology
Jing Yang, Yanping Sun, Feng Cao, Bingyou Yang, Haixue Kuang
Summary: This article reviews the structural analysis, quality control, pharmacology, and pharmacokinetics of Physalis alkekengi, a medicinal and edible plant commonly used in Chinese medicine. The article also discusses future research trends and perspectives for this plant. The chemical components of P. alkekengi include steroids, flavonoids, phenylpropanoids, and alkaloids, among others, and these components have shown extensive biological activities. The pharmacological potential of P. alkekengi is significant and further research on the pharmacokinetics of its compounds is needed.
Article
Plant Sciences
Aline Xavier de Souza, Markus Riederer, Jana Leide
Summary: This study analyzed the cuticle profiles of different plant species and compared the cuticle-related characteristics among organs. The study found that the composition, structure, and barrier function of the cuticle varied among different species and organs. Fruiting calyces were found to reduce water loss and enable fruit maturation within a protective microclimate, influencing seed dispersal strategies.
FRONTIERS IN PLANT SCIENCE
(2022)
Review
Plant Sciences
Lanyuan Liang, Chuanqiu Li, Yi Wang, Yimin Yue, Han Zhang, Mengru Yang, Xia Cao, Mantong Zhao, Jieyong Du, Mingming Peng, Ying Chen, Wei Li, Tianyi Xia, Renxing Zhong, Zunpeng Shu
Summary: This paper provides a comprehensive overview on the research progress of Physalis alkekengi L. var. franchetii (PAF), including its traditional application, botany, chemical composition, pharmacological effects, and toxicology. It also discusses new insights and suggestions for quality control and modern applications, addressing the limitations of pharmacological mechanism studies and quality control research. This review offers theoretical guidance for the clinical application and development of Chinese medicine.
Article
Biochemistry & Molecular Biology
Yuekun Wu, Lu Dong, Yujie Song, Yajing Wu, Yan Zhang, Shuo Wang
Summary: This study found that Physalis alkekengi L. fruit polysaccharide (PFP) can prevent insulin resistance induced by dietary advanced glycation end products (AGEs). PFP improved hyperglycemia, dyslipidemia, and insulin sensitivity in mice. The mechanism involves modulation of the gut microbiota and increased microbial metabolites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Environmental Sciences
Mohammad Javad Abdi, Marzieh Ghanbari Jahromi, Seyed Najmmaddin Mortazavi, Sepideh Kalateh Jari, Mohammad Javad Nazarideljou
Summary: This study investigated the effects of silicon and selenium nanoparticles on the growth and physiological attributes of Physalis alkekengi L. under salt stress. The results showed that nanoparticles can increase plant weight, chlorophyll content, and antioxidant levels, while reducing the negative effects of salt stress on plants.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
