Noncanonical STAT1 phosphorylation expands its transcriptional activity into promoting LPS-induced IL-6 and IL-12p40 production

STAT1 signaling shields T cells from NK cell-mediated cytotoxicity

(2019) Yu Hui Kang et al.   Nature Communications

Chanzyme TRPM7 Mediates the Ca 2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation

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Regulation of inflammatory responses by dynamic subcellular localization of RNA-binding protein Arid5a

(2018) Mitsuru Higa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IRF9 and unphosphorylated STAT2 cooperate with NF-κB to drive IL6 expression

(2018) Jing Nan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a

(2018) Nilesh Amatya et al.   Science Signaling

TLR4-induced NF-κB and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a

(2017) Kishan K. Nyati et al.   NUCLEIC ACIDS RESEARCH

JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework

(2017) Aziz Khan et al.   NUCLEIC ACIDS RESEARCH

Canonical and Non-Canonical Aspects of JAK–STAT Signaling: Lessons from Interferons for Cytokine Responses

(2017) Andrea Majoros et al.   Frontiers in Immunology

Raftlin Controls Lipopolysaccharide-Induced TLR4 Internalization and TICAM-1 Signaling in a Cell Type–Specific Manner

(2016) Megumi Tatematsu et al.   JOURNAL OF IMMUNOLOGY

Proteogenomics connects somatic mutations to signalling in breast cancer

(2016) Philipp Mertins et al.   NATURE

Arid5a exacerbates IFN-γ–mediated septic shock by stabilizing T-bet mRNA

(2016) Mohammad Mahabub-Uz Zaman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Pattern Recognition: A Cell Biological Perspective

(2015) Sky W. Brubaker et al.   Annual Review of Immunology

Forna (force-directed RNA): Simple and effective online RNA secondary structure diagrams

(2015) Peter Kerpedjiev et al.   BIOINFORMATICS

SalmonellaTyphimurium Co-Opts the Host Type I IFN System To Restrict Macrophage Innate Immune Transcriptional Responses Selectively

(2015) Darren J. Perkins et al.   JOURNAL OF IMMUNOLOGY

Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex

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Promoter Occupancy of STAT1 in Interferon Responses Is Regulated by Processive Transcription

(2014) Ivana Wiesauer et al.   MOLECULAR AND CELLULAR BIOLOGY

A Cross-Disciplinary Perspective on the Innate Immune Responses to Bacterial Lipopolysaccharide

(2014) Yunhao Tan et al.   MOLECULAR CELL

MCPIP1 negatively regulates toll-like receptor 4 signaling and protects mice from LPS-induced septic shock

(2013) Shengping Huang et al.   CELLULAR SIGNALLING

Arid5a controls IL-6 mRNA stability, which contributes to elevation of IL-6 level in vivo

(2013) Kazuya Masuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Building a Better Dynasore: The Dyngo Compounds Potently Inhibit Dynamin and Endocytosis

(2013) Adam McCluskey et al.   TRAFFIC

Folding RNA/DNA hybrid duplexes

(2012) Ronny Lorenz et al.   BIOINFORMATICS

Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

(2012) Nirmal Robinson et al.   NATURE IMMUNOLOGY

SIFTS: Structure Integration with Function, Taxonomy and Sequences resource

(2012) Sameer Velankar et al.   NUCLEIC ACIDS RESEARCH

STAT1-DEFICIENT MICE ARE RESISTANT TO CECAL LIGATION AND PUNCTURE–INDUCED SEPTIC SHOCK

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CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

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The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR–IL-1R by controlling degradation of regnase-1

(2011) Hidenori Iwasaki et al.   NATURE IMMUNOLOGY

The TRAF-associated protein TANK facilitates cross-talk within the I B kinase family during Toll-like receptor signaling

(2011) K. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acetylation of p65 at lysine 314 is important for late NF-κB-dependent gene expression

(2010) Karin M Rothgiesser et al.   BMC GENOMICS

Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay

(2009) Kazufumi Matsushita et al.   NATURE

Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes

(2009) H. Cheon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY