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Molecular Dynamics Simulation reveals the mechanism by which the Influenza Cap-dependent Endonuclease acquires resistance against Baloxavir marboxil

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Influenza A variants with reduced susceptibility to baloxavir isolated from Japanese patients are fit and transmit through respiratory droplets

(2019) Masaki Imai et al.   Nature Microbiology

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(2018) Young-A Heo   DRUGS

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The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit

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