Chronic mild hypoxia accelerates recovery from preexisting EAE by enhancing vascular integrity and apoptosis of infiltrated monocytes

Absence of endothelial α5β1 integrin triggers early onset of experimental autoimmune encephalomyelitis due to reduced vascular remodeling and compromised vascular integrity

(2019) Ravi Kant et al.   Acta Neuropathologica Communications

Csf1R inhibition attenuates experimental autoimmune encephalomyelitis and promotes recovery

(2018) Jillian C. Nissen et al.   EXPERIMENTAL NEUROLOGY

Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy

(2018) Carmen Navarrete et al.   Journal of Neuroinflammation

Hypoxic pre-conditioning suppresses experimental autoimmune encephalomyelitis by modifying multiple properties of blood vessels

(2018) Sebok K. Halder et al.   Acta Neuropathologica Communications

Therapeutic depletion of monocyte-derived cells protects from long-term axonal loss in experimental autoimmune encephalomyelitis

(2016) Monica A. Moreno et al.   JOURNAL OF NEUROIMMUNOLOGY

Endogenous adaptation to low oxygen modulates T-cell regulatory pathways in EAE

(2016) Nilufer Esen et al.   Journal of Neuroinflammation

Hypoxia as a therapy for mitochondrial disease

(2016) I. H. Jain et al.   SCIENCE

Gray Matter Hypoxia in the Brain of the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

(2016) Thomas W. Johnson et al.   PLoS One

Reduced cortical microvascular oxygenation in multiple sclerosis: a blinded, case-controlled study using a novel quantitative near-infrared spectroscopy method

(2015) Runze Yang et al.   Scientific Reports

Chronic intermittent hypoxic preconditioning suppresses pilocarpine-induced seizures and associated hippocampal neurodegeneration

(2014) Jun-li Zhen et al.   BRAIN RESEARCH

Multiple Sclerosis: Current and Emerging Disease-Modifying Therapies and Treatment Strategies

(2014) Dean M. Wingerchuk et al.   MAYO CLINIC PROCEEDINGS

Neurological deficits caused by tissue hypoxia in neuroinflammatory disease

(2013) Andrew L. Davies et al.   ANNALS OF NEUROLOGY

Extensive vascular remodeling in the spinal cord of pre-symptomatic experimental autoimmune encephalomyelitis mice; increased vessel expression of fibronectin and the α5β1 integrin

(2013) Amin Boroujerdi et al.   EXPERIMENTAL NEUROLOGY

Repetitive hypoxia extends endogenous neurovascular protection for stroke

(2011) Ann M. Stowe et al.   ANNALS OF NEUROLOGY

Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions

(2011) Timothy J Seabrook et al.   Journal of Neuroinflammation

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

(2011) Bahareh Ajami et al.   NATURE NEUROSCIENCE

In the hypoxic central nervous system, endothelial cell proliferation is followed by astrocyte activation, proliferation, and increased expression of the α6β4 integrin and dystroglycan

(2010) Longxuan Li et al.   GLIA

Increased blood vessel density and endothelial cell proliferation in multiple sclerosis cerebral white matter

(2009) Janet E. Holley et al.   NEUROSCIENCE LETTERS

B cells limit epitope spreading and reduce severity of EAE induced with PLP peptide in BALB/c mice

(2008) Jeri-Anne Lyons et al.   JOURNAL OF AUTOIMMUNITY

Increased expression of fibronectin and the α5β1 integrin in angiogenic cerebral blood vessels of mice subject to hypobaric hypoxia

(2008) Richard Milner et al.   MOLECULAR AND CELLULAR NEUROSCIENCE