Arrestin domain-containing 3 (Arrdc3) modulates insulin action and glucose metabolism in liver

Multi-dimensional Transcriptional Remodeling by Physiological Insulin In Vivo

(2019) Thiago M. Batista et al.   Cell Reports

Mice Carrying a Dominant-Negative Human PI3K Mutation Are Protected From Obesity and Hepatic Steatosis but Not Diabetes

(2018) Marie H. Solheim et al.   DIABETES

Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression

(2017) Weikang Cai et al.   Nature Communications

Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling

(2017) Shannon H. Carroll et al.   PLoS One

Androgen receptor regulated microRNA miR-182-5p promotes prostate cancer progression by targeting the ARRDC3/ITGB4 pathway

(2016) Jingjing Yao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β2-Adrenergic Receptor

(2016) Xufan Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization

(2015) InSug O-Sullivan et al.   Nature Communications

Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors

(2014) Rebecca A. Haeusler et al.   Nature Communications

Structural and Biochemical Basis for Ubiquitin Ligase Recruitment by Arrestin-related Domain-containing Protein-3 (ARRDC3)

(2013) Shiqian Qi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct roles for β-arrestin2 and arrestin-domain-containing proteins in β2 adrenergic receptor trafficking

(2012) Sang-Oh Han et al.   EMBO REPORTS

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

(2012) Mingjian Lu et al.   NATURE MEDICINE

An expanded family of arrestins regulate metabolism

(2012) Parth Patwari et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Arrestin Domain-Containing 3 Protein Regulates Body Mass and Energy Expenditure

(2011) Parth Patwari et al.   Cell Metabolism

Deletion of the  -Arrestin Protein Txnip in Mice Promotes Adiposity and Adipogenesis While Preserving Insulin Sensitivity

(2010) W. A. Chutkow et al.   DIABETES

Arrestin domain-containing protein 3 recruits the NEDD4 E3 ligase to mediate ubiquitination of the β2-adrenergic receptor

(2010) Joseph F Nabhan et al.   EMBO REPORTS

ARRDC3 suppresses breast cancer progression by negatively regulating integrin β4

(2010) K M Draheim et al.   ONCOGENE

Portal glucose infusion-glucose clamp measures hepatic influence on postprandial systemic glucose appearance as well as whole body glucose disposal

(2009) Dan Zheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Thioredoxin-independent Regulation of Metabolism by the α-Arrestin Proteins

(2009) Parth Patwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Combination of HNF-4 and Foxo1 Is Required for Reciprocal Transcriptional Regulation of Glucokinase and Glucose-6-phosphatase Genes in Response to Fasting and Feeding

(2008) Keiko Hirota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signaling networks assembled by oncogenic EGFR and c-Met

(2008) A. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA