Applying univariate vs. multivariate statistics to investigate therapeutic efficacy in (pre)clinical trials: A Monte Carlo simulation study on the example of a controlled preclinical neurotrauma trial
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Title
Applying univariate vs. multivariate statistics to investigate therapeutic efficacy in (pre)clinical trials: A Monte Carlo simulation study on the example of a controlled preclinical neurotrauma trial
Authors
Keywords
Principal component analysis, Research errors, Simulation and modeling, Analysis of variance, Neurotrauma, Ellipses, Test statistics, Monte Carlo method
Journal
PLoS One
Volume 15, Issue 3, Pages e0230798
Publisher
Public Library of Science (PLoS)
Online
2020-03-27
DOI
10.1371/journal.pone.0230798
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