Article
Oncology
Jue Li, Yan Wang, Yanming Wu, Jialong Li, Guowei Che
Summary: The research on pretreatment AGR in lung cancer patients found a significant correlation between low AGR and poor overall survival and disease-free survival. This indicator has potential value and stability in prognostic prediction.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
(2021)
Review
Oncology
Jiali Leng, Fei Wu, Lihui Zhang
Summary: This meta-analysis found that pretreatment neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) may serve as biomarkers for predicting poor prognosis in patients with endometrial cancer, while monocyte-lymphocyte ratio (MLR) is not associated with prognosis.
FRONTIERS IN ONCOLOGY
(2022)
Article
Multidisciplinary Sciences
Si-Min Peng, Jin-Jin Ren, Na Yu, Jia-Ying Xu, Guo-Chong Chen, Xiaodong Li, Da-Peng Li, Jing Yang, Zeng-Ning Li, Yu-Song Zhang, Li-Qiang Qin
Summary: The Naples prognostic score (NPS) is a valuable prognostic factor for non-small-cell lung cancer (NSCLC) patients, as it is associated with overall survival (OS) and progress-free survival (PFS). NPS is an independent prognostic factor for OS and PFS, and it has predictive performance in different stages of NSCLC.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Yan Wang, Chu Xu, Zongxin Zhang
Summary: This meta-analysis study demonstrated that a low lymphocyte-to-monocyte ratio (LMR) is significantly associated with poor overall survival (OS) in glioma patients. However, there is no significant correlation between LMR and progression-free survival (PFS) in glioma patients. Subgroup analysis indicated that a low LMR is significantly associated with inferior OS and PFS in glioma when using a cutoff value of <= 3.7 or when patients received mixed treatment.
Article
Oncology
Feng Wang, Limin Chen, Zhao Wang, Qiuyan Xu, He Huang, Hairong Wang, Xi Li, Mingjie Yu, Jiangen Chen, Fuhua Lin, Zhenghe Chen, Xiangheng Zhang, Qunying Yang, Yonggao Mou, Chengcheng Guo
Summary: This study aimed to explore the predictive value of pretreatment inflammatory biomarkers and establish a novel prognostic index for NSCLC patients with BM.
CANCER CELL INTERNATIONAL
(2022)
Review
Oncology
Bowen Xu, Zhiqiang Chen, Jing Zhang, Jianhua Chang, Wei Zhao, Zhaoru Dong, Xuting Zhi, Tao Li
Summary: The study confirmed the importance of whole blood cell count-derived indexes including NLR, MLR/LMR, and PLR as prognostic parameters for GBC patients, and can be used to predict survival outcomes, helping to improve risk stratification and patient selection.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Jiyun Park, Jun Park, Jung Hee Shin, Young-Lyun Oh, Hyun-Ae Jung, Man-Ki Chung, Jun-Ho Choe, Yong-Chan Ahn, Sun-Wook Kim, Jae-Hoon Chung, Tae-Hyuk Kim, Jae-Myoung Noh
Summary: The study found that high NLR before and after radiotherapy was associated with poor survival in patients with anaplastic thyroid cancer (ATC), indicating the importance of host immunity in ATC patients. This suggests that this finding may provide important information for designing future investigations on the impact of immune system modulating therapy in ATC.
Review
Oncology
Qianning Zhang, Xiaoling Gong, Lei Sun, Liyun Miao, Yujie Zhou
Summary: The meta-analysis investigated the predictive value of pretreatment LDH and dNLR for NSCLC progression in patients treated with PD-1/PD-L1 inhibitors. High pretreatment LDH was associated with poor overall survival, while high pretreatment dNLR was related to poor overall survival and progression-free survival in advanced NSCLC patients.
FRONTIERS IN ONCOLOGY
(2022)
Article
Respiratory System
Ricard Ramos, Ivan Macia, Arturo Navarro-Martin, Carlos Deniz, Francisco Rivas, Anna Urena, Cristina Masuet-Aumatell, Camilo Moreno, Ernest Nadal, Ignacio Escobar
Summary: The lymphocyte-to-monocyte ratio (LMR) is an independent prognostic factor for overall survival and recurrence-free survival in patients with surgically-resected early stage lung cancer.
BMC PULMONARY MEDICINE
(2021)
Article
Oncology
Alex K. K. Bryant, Kamya Sankar, Garth W. W. Strohbehn, Lili Zhao, David Elliott, Angel Qin, Sarah Yentz, Nithya Ramnath, Michael D. D. Green
Summary: This study demonstrates that pre-treatment NLR is a prognostic factor in stage III NSCLC patients treated with adjuvant immunotherapy, and it may also serve as a predictive biomarker of immunotherapy benefit.
Review
Oncology
Xianyang Hu, Tengfei Tian, Qin Sun, Wenxiu Jiang
Summary: This meta-analysis study investigated the relationship between high neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) and laryngeal cancer prognosis. The results showed that high NLR was associated with poor overall survival, progression-free survival, and disease-free survival, while high PLR was linked to poor overall survival.
FRONTIERS IN ONCOLOGY
(2022)
Review
Oncology
Jing Jin, Lan Yang, Dan Liu, Wei Min Li
Summary: The meta-analysis findings showed that decreased pretreatment LMR in peripheral blood was significantly associated with shorter progression-free survival (PFS) and overall survival (OS) in lung cancer patients, indicating its potential prognostic value.
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
(2021)
Review
Surgery
Nanping Lin, Jingrong Li, Xiangqing Yao, Xiang Zhang, Guozhong Liu, Zhibo Zhang, Shangeng Weng
Summary: The neutrophil-to-lymphocyte ratio (NLR) has prognostic value in colorectal cancer liver metastasis (CRLM), with elevated NLR being associated with poor overall survival and disease-free survival. Patients with normal NLR have higher 5-year overall survival and disease-free survival rates. NLR can be used for treatment decision-making and predicting clinical outcomes in CRLM.
INTERNATIONAL JOURNAL OF SURGERY
(2022)
Article
Oncology
Toshiki Ogiwara, Hitoshi Kawazoe, Saeka Egami, Hironobu Hashimoto, Yoshimasa Saito, Naomi Sakiyama, Yuichiro Ohe, Masakazu Yamaguchi, Tetsuya Furukawa, Azusa Hara, Yui Hiraga, Aya Jibiki, Yuta Yokoyama, Sayo Suzuki, Tomonori Nakamura
Summary: The combination of baseline medications with nivolumab or pembrolizumab and neutrophil-to-lymphocyte ratio (NLR) may lead to shorter survival outcomes in patients with advanced NSCLC and serve as a prognostic index for poor outcomes. A significant association was found between the prognostic score and overall survival (OS) in 259 patients, but not with progression-free survival (PFS). Further validation in a large-scale multicenter study is needed to confirm these findings for clinical application.
FRONTIERS IN ONCOLOGY
(2021)
Review
Surgery
Francesca Savioli, Elizabeth S. Morrow, Ross D. Dolan, Laszlo Romics, Alison Lannigan, Joanne Edwards, Donald C. McMillan
Summary: Through a systematic review and meta-analysis, it was found that preoperative circulating markers of the systemic inflammatory response, such as NLR, dNLR, LMR, PLR, and CRP, may serve as prognostic markers in primary operable breast cancer.
BRITISH JOURNAL OF SURGERY
(2022)
Article
Multidisciplinary Sciences
Yan Lu, Haoyang Guo, Xuya Chen, Qiaohong Zhang
Summary: LAR demonstrates better predictive value in predicting 30-day mortality of acute respiratory failure patients, and high LAR is positively correlated with all-cause mortality. This study suggests further verification of LAR's clinical potential through multi-center prospective studies.