Functional analysis of proposed substrate-binding residues of Hsp104
Published 2020 View Full Article
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Title
Functional analysis of proposed substrate-binding residues of Hsp104
Authors
Keywords
Toxicity, Yeast, Tyrosine, Glucose, Alanine, Amyotrophic lateral sclerosis, DNA-binding proteins, Electron cryo-microscopy
Journal
PLoS One
Volume 15, Issue 3, Pages e0230198
Publisher
Public Library of Science (PLoS)
Online
2020-03-11
DOI
10.1371/journal.pone.0230198
References
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- (2017) Stephanie N. Gates et al. SCIENCE
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- (2016) Mariana P. Torrente et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2016) Adam L Yokom et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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- Potentiated Hsp104 variants suppress toxicity of diverse neurodegenerative disease-linked proteins
- (2014) M. E. Jackrel et al. Disease Models & Mechanisms
- Blessings in disguise: biological benefits of prion-like mechanisms
- (2013) Gregory A. Newby et al. TRENDS IN CELL BIOLOGY
- Operational Plasticity Enables Hsp104 to Disaggregate Diverse Amyloid and Nonamyloid Clients
- (2012) Morgan E. DeSantis et al. CELL
- Peptide and Protein Binding in the Axial Channel of Hsp104
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- (2008) Peter Tessarz et al. MOLECULAR MICROBIOLOGY
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