Intranasal administration of dantrolene increased brain concentration and duration

Ryanodine receptors contribute to the induction of ischemic tolerance

(2016) Emi Nakamura-Maruyama et al.   BRAIN RESEARCH BULLETIN

Long-term Dantrolene Treatment Reduced Intraneuronal Amyloid in Aged Alzheimer Triple Transgenic Mice

(2015) Zhen Wu et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Intranasal pyrrolidine dithiocarbamate decreases brain inflammatory mediators and provides neuroprotection after brain hypoxia–ischemia in neonatal rats

(2013) Zhi Wang et al.   EXPERIMENTAL NEUROLOGY

Disruption of Calcium Homeostasis in Cardiomyocytes Underlies Cardiac Structural and Functional Changes in Severe Sepsis

(2013) Mara R. N. Celes et al.   PLoS One

Early and chronic treatment with dantrolene blocked later learning and memory deficits in older Alzheimer's triple transgenic mice

(2012) Jun Peng et al.   Alzheimers & Dementia

Ryanodine Receptor Blockade Reduces Amyloid-  Load and Memory Impairments in Tg2576 Mouse Model of Alzheimer Disease

(2012) B. Oules et al.   JOURNAL OF NEUROSCIENCE

Intranasal delivery of insulin via the olfactory nerve pathway

(2012) Dan B. Renner et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Dantrolene is neuroprotective in vitro, but does not affect survival in SOD1G93A mice

(2012) K.A. Staats et al.   NEUROSCIENCE

Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice

(2012) Jun Peng et al.   NEUROSCIENCE LETTERS

Stabilizing ER Ca2+ Channel Function as an Early Preventative Strategy for Alzheimer’s Disease

(2012) Shreaya Chakroborty et al.   PLoS One

Intranasal delivery of biologics to the central nervous system

(2011) Jeffrey J. Lochhead et al.   ADVANCED DRUG DELIVERY REVIEWS

Quantitative Evaluation of the Impact of Active Efflux by P-Glycoprotein and Breast Cancer Resistance Protein at the Blood-Brain Barrier on the Predictability of the Unbound Concentrations of Drugs in the Brain Using Cerebrospinal Fluid Concentration as a Surrogate

(2011) H. Kodaira et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Dantrolene is neuroprotective in Huntington's disease transgenic mouse model

(2011) Xi Chen et al.   Molecular Neurodegeneration

The Cytoprotective Effects of Dantrolene

(2010) Saadet Inan et al.   ANESTHESIA AND ANALGESIA

Cardiac Arrests and Deaths Associated with Malignant Hyperthermia in North America from 1987 to 2006

(2009) Marilyn Green Larach et al.   ANESTHESIOLOGY

Intranasal delivery to the central nervous system: Mechanisms and experimental considerations

(2009) Shyeilla V. Dhuria et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Deranged Calcium Signaling and Neurodegeneration in Spinocerebellar Ataxia Type 3

(2008) X. Chen et al.   JOURNAL OF NEUROSCIENCE

Delivery of interferon-β to the monkey nervous system following intranasal administration

(2008) R.G. Thorne et al.   NEUROSCIENCE

Can Dantrolene Protect Spinal Cord against Ischemia/Reperfusion Injury? An Experimental Study

(2008) C. Kocogullari et al.   THORACIC AND CARDIOVASCULAR SURGEON