Physcion inhibits the metastatic potential of human colorectal cancer SW620 cells in vitro by suppressing the transcription factor SOX2

SOX2, a predictor of survival in gastric cancer, inhibits cell proliferation and metastasis by regulating PTEN

(2015) Simeng Wang et al.   CANCER LETTERS

Dihydromyricetin Activates AMP-Activated Protein Kinase and P38MAPK Exerting Antitumor Potential in Osteosarcoma

(2014) Z. Zhao et al.   Cancer Prevention Research

Quercetin reverses EGF-induced epithelial to mesenchymal transition and invasiveness in prostate cancer (PC-3) cell line via EGFR/PI3K/Akt pathway

(2014) Firdous Ahmad Bhat et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells

(2014) R Santini et al.   ONCOGENE

Increased SOX2 Gene Copy Number Is Associated with FGFR1 and PIK3CA Gene Gain in Non-Small Cell Lung Cancer and Predicts Improved Survival in Early Stage Disease

(2014) Luca Toschi et al.   PLoS One

SOX2 overexpression correlates with poor prognosis in laryngeal squamous cell carcinoma

(2013) Xia-bing Tang et al.   AURIS NASUS LARYNX

The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells

(2013) Katharina Hütz et al.   CARCINOGENESIS

SOX2 regulates apoptosis through MAP4K4-Survivin signaling pathway in human lung cancer cells

(2013) Si Chen et al.   CARCINOGENESIS

Sox2 expression predicts poor survival of hepatocellular carcinoma patients and it promotes liver cancer cell invasion by activating Slug

(2013) Chun Sun et al.   MEDICAL ONCOLOGY

Physcion from marine-derived fungus Microsporum sp. induces apoptosis in human cervical carcinoma HeLa cells

(2013) Isuru Wijesekara et al.   MICROBIOLOGICAL RESEARCH

Metformin reverses multidrug resistance and epithelial–mesenchymal transition (EMT) via activating AMP-activated protein kinase (AMPK) in human breast cancer cells

(2013) Chen Qu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Metformin Blocks Melanoma Invasion and Metastasis Development in AMPK/p53-Dependent Manner

(2013) M. Cerezo et al.   MOLECULAR CANCER THERAPEUTICS

Autophagy and Cellular Senescence Mediated by Sox2 Suppress Malignancy of Cancer Cells

(2013) Yong-Yeon Cho et al.   PLoS One

Epithelial-Mesenchymal Transition Associates with Maintenance of Stemness in Spheroid-Derived Stem-Like Colon Cancer Cells

(2013) Xiao-Yan Han et al.   PLoS One

SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells

(2013) M Herreros-Villanueva et al.   Oncogenesis

Sex-determining region Y-box 2 expression predicts poor prognosis in human ovarian carcinoma

(2012) Jing Zhang et al.   HUMAN PATHOLOGY

Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer

(2012) Sabine Stolzenburg et al.   NUCLEIC ACIDS RESEARCH

Silencing SOX2 Induced Mesenchymal-Epithelial Transition and Its Expression Predicts Liver and Lymph Node Metastasis of CRC Patients

(2012) Xu Han et al.   PLoS One

Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression

(2011) Hak-Su Kim et al.   BIOCHEMICAL PHARMACOLOGY

SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer

(2011) Jens Neumann et al.   BMC CANCER

Activation of AMP-activated Protein Kinase Is Essential for Lysophosphatidic Acid-induced Cell Migration in Ovarian Cancer Cells

(2011) Eung-Kyun Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic and Epigenetic Modifications of Sox2 Contribute to the Invasive Phenotype of Malignant Gliomas

(2011) Marta M. Alonso et al.   PLoS One

Comprehensive analysis of clinical significance of stem-cell related factors in renal cell cancer

(2011) Yongchao Liu et al.   World Journal of Surgical Oncology

SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell

(2011) X. Jia et al.   Journal of Molecular Cell Biology

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Regulation of Lung Cancer Cell Migration and Invasion by Reactive Oxygen Species and Caveolin-1

(2010) Sudjit Luanpitpong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-inflammatory and anticancer compounds isolated fromVentilago madraspatanaGaertn.,Rubia cordifoliaLinn. andLantana camaraLinn.

(2010) Subhalakshmi Ghosh et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

ChIP-seq and Functional Analysis of the SOX2 Gene in Colorectal Cancers

(2010) Xuefeng Fang et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

AMP-activated protein kinase and cancer

(2009) W. Wang et al.   Acta Physiologica

Green Tea Catechin Controls Apoptosis in Colon Cancer Cells by Attenuation of H2O2-Stimulated COX-2 Expression via the AMPK Signaling Pathway at Low-Dose H2O2

(2009) In-Ja Park et al.   Annals of the New York Academy of Sciences

Investigations of Free Anthraquinones from Rhubarb Against α-Naphthylisothiocyanate-induced Cholestatic Liver Injury in Rats

(2009) Yan-Ling Zhao et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Antimicrobial activities of methanol extract and compounds from stem bark of Vismia rubescens

(2009) Jean De Dieu Tamokou et al.   JOURNAL OF ETHNOPHARMACOLOGY

Oxidative Stress Is Inherent in Prostate Cancer Cells and Is Required for Aggressive Phenotype

(2008) B. Kumar et al.   CANCER RESEARCH

Regulation of Self-Renewal and Pluripotency by Sox2 in Human Embryonic Stem Cells

(2008) Helen Fong et al.   STEM CELLS