A selective D3 receptor antagonist YQA14 attenuates methamphetamine-induced behavioral sensitization and conditioned place preference in mice

Characterization of preclinicalin vitroandin vivoADME properties and prediction of human PK using a physiologically based pharmacokinetic model for YQA-14, a new dopamine D3receptor antagonist candidate for treatment of drug addiction

(2014) Fei Liu et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

A novel dopamine D3 receptor antagonist YQA14 inhibits methamphetamine self-administration and relapse to drug-seeking behaviour in rats

(2014) Ying Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The novel dopamine D3 receptor antagonist, SR 21502, reduces cocaine conditioned place preference in rats

(2014) P. Hachimine et al.   NEUROSCIENCE LETTERS

The dopamine D3 receptor antagonist YQA14 that inhibits the expression and drug-primed reactivation of morphine-induced conditioned place preference in rats

(2013) Rongrong Hu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dopamine D3 receptor deletion or blockade attenuates cocaine-induced conditioned place preference in mice

(2013) Rui Song et al.   NEUROPHARMACOLOGY

Blockade of D3 receptors by YQA14 inhibits cocaine's rewarding effects and relapse to drug-seeking behavior in rats

(2013) Rui Song et al.   NEUROPHARMACOLOGY

The effects of the novel DA D3 receptor antagonist SR 21502 on cocaine reward, cocaine seeking and cocaine-induced locomotor activity in rats

(2013) E. Galaj et al.   PSYCHOPHARMACOLOGY

Drink, drugs and disruption: memory manipulation for the treatment of addiction

(2012) AL Milton   CURRENT OPINION IN NEUROBIOLOGY

Higher Binding of the Dopamine D3 Receptor-Preferring Ligand [11C]-(+)-Propyl-Hexahydro-Naphtho-Oxazin in Methamphetamine Polydrug Users: A Positron Emission Tomography Study

(2012) I. Boileau et al.   JOURNAL OF NEUROSCIENCE

Increased vulnerability to cocaine in mice lacking dopamine D3 receptors

(2012) R. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Memory Retrieval-Extinction Procedure to Prevent Drug Craving and Relapse

(2012) Y.-X. Xue et al.   SCIENCE

YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice

(2011) Rui Song et al.   ADDICTION BIOLOGY

Dopamine D3 receptor antagonist SB-277011A inhibits methamphetamine self-administration and methamphetamine-induced reinstatement of drug-seeking in rats

(2011) Amanda E. Higley et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Distinct roles of dopamine D3 receptors in modulating methamphetamine-induced behavioral sensitization and ultrastructural plasticity in the shell of the nucleus accumbens

(2011) Jie Zhu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Drug Wanting: Behavioral Sensitization and Relapse to Drug-Seeking Behavior

(2011) J. D. Steketee et al.   PHARMACOLOGICAL REVIEWS

Current perspectives on selective dopamine D3 receptor antagonists as pharmacotherapeutics for addictions and related disorders

(2010) Christian A. Heidbreder et al.   Annals of the New York Academy of Sciences

Double Dissociation of the Effects of Haloperidol and the Dopamine D3 Receptor Antagonist ABT-127 on Acquisition vs. Expression of Cocaine-Conditioned Activity in Rats

(2010) T. J. Banasikowski et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

PG01037, a novel dopamine D3 receptor antagonist, inhibits the effects of methamphetamine in rats

(2010) Amanda E Higley et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Regional specificity in the real-time development of phasic dopamine transmission patterns during acquisition of a cue-cocaine association in rats

(2009) Brandon J. Aragona et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dopaminergic mechanism of reward-related incentive learning: Focus on the dopamine d3 receptor

(2009) Richard J. Beninger et al.   NEUROTOXICITY RESEARCH

Targeting extinction and reconsolidation mechanisms to combat the impact of drug cues on addiction

(2008) Jane R. Taylor et al.   NEUROPHARMACOLOGY

Dopamine increases in striatum do not elicit craving in cocaine abusers unless they are coupled with cocaine cues

(2007) Nora D. Volkow et al.   NEUROIMAGE