The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway

Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways

(2013) Jia Xiao et al.   EUROPEAN JOURNAL OF NUTRITION

Molecular pathogenesis of chronic cholestatic liver disease: Impact on novel therapeutic approaches

(2013) Peter Fickert et al.   MOLECULAR ASPECTS OF MEDICINE

Phase 2 trial of daily, oral polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia

(2012) Tait D. Shanafelt et al.   CANCER

GAP161 targets and downregulates G3BP to suppress cell growth and potentiate cisplaitin-mediated cytotoxicity to colon carcinoma HCT116 cells

(2012) Hao Zhang et al.   CANCER SCIENCE

Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications

(2011) Brahma N. Singh et al.   BIOCHEMICAL PHARMACOLOGY

Epigallocatechin Gallate Suppresses Lung Cancer Cell Growth through Ras-GTPase-Activating Protein SH3 Domain-Binding Protein 1

(2010) J. H. Shim et al.   Cancer Prevention Research

Bile salts and cholestasis

(2010) Lucas Maillette de Buy Wenniger et al.   DIGESTIVE AND LIVER DISEASE

Pathogenesis of Cholestatic Liver Disease and Therapeutic Approaches

(2010) Gideon M. Hirschfield et al.   GASTROENTEROLOGY

Combination of retinoic acid and ursodeoxycholic acid attenuates liver injury in bile duct-ligated rats and human hepatic cells

(2010) Hongwei He et al.   HEPATOLOGY

Epigallocatechin-3-gallate (EGCG) reduces liver inflammation, oxidative stress and fibrosis in carbon tetrachloride (CCl4)-induced liver injury in mice

(2010) George L. Tipoe et al.   TOXICOLOGY

(−)-Epigallocatechin gallate prevents carbon tetrachloride-induced rat hepatic fibrosis by inhibiting the expression of the PDGFRβ and IGF-1R

(2009) Yoichi Yasuda et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Hepatic fibrosis—Overview

(2008) Scott L. Friedman   TOXICOLOGY