Insulin deficiency promotes formation of toxic amyloid-β42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model

Published 2020 View Full Article

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Title
Insulin deficiency promotes formation of toxic amyloid-β42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model
Authors
Keywords
Alzheimer's disease, Animal model, 3xTg-AD mouse, Toxic amyloid β conformer, Insulin deficiency, Insulin resistance, Tau oligomer, Insulin signaling, Microglia
Journal
NEUROBIOLOGY OF DISEASE
Volume 137, Issue -, Pages 104739
Publisher
Elsevier BV
Online
2020-01-10
DOI
10.1016/j.nbd.2020.104739

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