Enhanced Immune Response Against the Thomsen-Friedenreich Tumor Antigen Using a Bivalent Entirely Carbohydrate Conjugate

Synthesis of glycoimmunogen Tn-Thr-PS A1 via hydrazone bond and stability optimization of PS A1 monosaccharide mimics under vaccine development conditions

(2020) F. Hossain et al.   JOURNAL OF CARBOHYDRATE CHEMISTRY

Specific features of human monocytes activation by monophosphoryl lipid A

(2018) Ryme Chentouh et al.   Scientific Reports

Flexible Signaling of Myeloid C-Type Lectin Receptors in Immunity and Inflammation

(2018) Carlos del Fresno et al.   Frontiers in Immunology

An innovative immunotherapeutic strategy for ovarian cancer: CLEC10A and glycomimetic peptides

(2018) Laura L. Eggink et al.   Journal for ImmunoTherapy of Cancer

Interactions between the breast cancer-associated MUC1 mucins and C-type lectin characterized by optical tweezers

(2017) Soosan Hadjialirezaei et al.   PLoS One

Synthesis and Evaluation of Glycoconjugates ComprisingN-Acyl-Modified Thomsen-Friedenreich Antigens as Anticancer Vaccines

(2016) Shuang Sun et al.   ChemMedChem

Sialyl-Tn Polysaccharide A1 as an Entirely Carbohydrate Immunogen: Synthesis and Immunological Evaluation

(2016) Mengchao Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Immunological evaluation of the entirely carbohydrate-based Thomsen-Friedenreich – PS B conjugate

(2016) Kevin R. Trabbic et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and biological evaluation of a novel MUC1 glycopeptide conjugate vaccine candidate comprising a 4’-deoxy-4’-fluoro-Thomsen–Friedenreich epitope

(2015) Manuel Johannes et al.   Beilstein Journal of Organic Chemistry

The Macrophage Galactose-Type C-Type Lectin (MGL) Modulates Regulatory T Cell Functions

(2015) Ilaria Grazia Zizzari et al.   PLoS One

MGL Receptor and Immunity: When the Ligand Can Make the Difference

(2015) Ilaria Grazia Zizzari et al.   Journal of Immunology Research

IL-10: The Master Regulator of Immunity to Infection

(2014) Kevin N. Couper et al.   JOURNAL OF IMMUNOLOGY

Proteomic analysis of cancer and mesothelial cells reveals an increase in Mucin 5AC during ovarian cancer and peritoneal interaction

(2014) Natasha Musrap et al.   Journal of Proteomics

Synthesis of the tumor associative α-aminooxy disaccharide of the TF antigen and its conjugation to a polysaccharide immune stimulant

(2014) Jean Paul Bourgault et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Mechanisms of Action of Adjuvants

(2013) Sunita Awate et al.   Frontiers in Immunology

The entirely carbohydrate immunogen Tn-PS A1 induces a cancer cell selective immune response and cytokine IL-17

(2012) Ravindra A. De Silva et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Human TH17 Immune Cells Specific for the Tumor Antigen MAGE-A3 Convert to IFN- -Secreting Cells as They Differentiate into Effector T Cells In Vivo

(2012) A. Hamai et al.   CANCER RESEARCH

A C-Linked Disaccharide Analogue of Thomsen-Friedenreich Epitope Induces a Strong Immune Response in Mice

(2012) Loay Awad et al.   CHEMISTRY-A EUROPEAN JOURNAL

Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation

(2012) Chiara Napoletano et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

ELISPOT Assay for Monitoring Cytotoxic T Lymphocytes (CTL) Activity in Cancer Vaccine Clinical Trials

(2012) Anatoli M. Malyguine et al.   Cells

Cancer vaccines and carbohydrate epitopes

(2011) Jamie Heimburg-Molinaro et al.   VACCINE

C-type Lectin Receptors for Tumor Eradication: Future Directions

(2011) Ingeborg Streng-Ouwehand et al.   Cancers

Synthetic Antitumor Vaccines from Tetanus Toxoid Conjugates of MUC1 Glycopeptides with the Thomsen-Friedenreich Antigen and a Fluorine-Substituted Analogue

(2010) Anja Hoffmann-Röder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant

(2010) T. Freire et al.   BLOOD

In vivo tumor cell adhesion in the pulmonary microvasculature is exclusively mediated by tumor cell - endothelial cell interaction

(2010) Peter Gassmann et al.   BMC CANCER

Tumour-associated glycan modifications of antigen enhance MGL2 dependent uptake and MHC class I restricted CD8 T cell responses

(2010) Satwinder Kaur Singh et al.   INTERNATIONAL JOURNAL OF CANCER

Tn Glycosylation of the MUC6 Protein Modulates Its Immunogenicity and Promotes the Induction of Th17-biased T Cell Responses

(2010) Teresa Freire et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distribution and Function of Macrophage Galactose-type C-type Lectin 2 (MGL2/CD301b)

(2010) Kaori Denda-Nagai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proinflammatory T helper type 17 cells are effective B-cell helpers

(2010) M. Mitsdoerffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research

(2009) M. A. Cheever et al.   CLINICAL CANCER RESEARCH

Targeted glycoproteomic identification of cancer cell glycosylation

(2009) Alex S Powlesland et al.   GLYCOBIOLOGY

T Helper 17 Cells Promote Cytotoxic T Cell Activation in Tumor Immunity

(2009) Natalia Martin-Orozco et al.   IMMUNITY

Immunological Response from an Entirely Carbohydrate Antigen: Design of Synthetic Vaccines Based on Tn−PS A1 Conjugates

(2009) Ravindra A. De Silva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization of murine MGL1 and MGL2 C-type lectins: Distinct glycan specificities and tumor binding properties

(2009) Satwinder Kaur Singh et al.   MOLECULAR IMMUNOLOGY

Sweet preferences of MGL: carbohydrate specificity and function

(2008) Sandra J. van Vliet et al.   TRENDS IN IMMUNOLOGY

The amino acids involved in the distinct carbohydrate specificities between macrophage galactose-type C-type lectins 1 and 2 (CD301a and b) of mice

(2007) Sarawut Oo-puthinan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS