4.8 Editorial Material

Splice or Die: When MYC Is Driving, Transcription Needs NUAK1 to Avoid Fatal Pileups

Journal

MOLECULAR CELL
Volume 77, Issue 6, Pages 1157-1158

Publisher

CELL PRESS
DOI: 10.1016/j.molcel.2020.02.025

Keywords

-

Funding

  1. NIGMS NIH HHS [R35 GM127289] Funding Source: Medline

Ask authors/readers for more resources

In this issue of Molecular Cell, Cossa et al. (2020) uncover the basis for a dependency of tumor cells with deregulated MYC on the kinase NUAK1, which acts through PP1 and PNUTS to ensure that splicing keeps up with MYC-driven transcription.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available