Journal
MOLECULAR CELL
Volume 77, Issue 5, Pages 930-931Publisher
CELL PRESS
DOI: 10.1016/j.molcel.2020.02.013
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Okazaki and colleagues report that PD-1 signaling mainly restrains effector function at the early stage of T cell activation. The authors find that cytokine genes require strong antigen stimulation and are more susceptible to PD-1 inhibition.
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