Article
Multidisciplinary Sciences
Yong Ge, Wen-Bin Zhang, Xilin Wu, Corrine W. Ruktanonchai, Haiyan Liu, Jianghao Wang, Yongze Song, Mengxiao Liu, Wei Yan, Juan Yang, Eimear Cleary, Sarchil H. Qader, Fatumah Atuhaire, Nick W. Ruktanonchai, Andrew J. Tatem, Shengjie Lai
Summary: Non-pharmaceutical interventions (NPIs) and COVID-19 vaccination have been implemented concurrently, making their relative effects difficult to measure. Here, the authors show that effects of NPIs reduced as vaccine coverage increased, but that NPIs could still be important in the context of more transmissible variants.
NATURE COMMUNICATIONS
(2022)
Article
Medicine, General & Internal
Ariel Hammerman, Ruslan Sergienko, Michael Friger, Tanya Beckenstein, Alon Peretz, Doron Netzer, Shlomit Yaron, Ronen Arbel
Summary: This retrospective cohort study in Israel found that receiving at least one dose of the BNT162b2 vaccine was associated with a significantly lower risk of recurrent infection among patients who had recovered from Covid-19. Vaccine effectiveness was similar for one dose and two doses.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Immunology
Kimberly H. Nguyen, Jing Huang, Kathrine Mansfield, Laura Corlin, Jennifer D. Allen
Summary: There are gaps in COVID-19 vaccine coverage in the United States, with lower vaccination rates among individuals with previous COVID-19 diagnoses and higher vaccine hesitancy among them. It is important to focus on adults who receive a COVID-19 diagnosis during clinic visits or at the time of discharge if hospitalized and educate the public about the value of being vaccinated regardless of previous infection.
EMERGING INFECTIOUS DISEASES
(2022)
Article
Multidisciplinary Sciences
Aashish Contractor, Shashikala Shivaprakash, Anjali Tiwari, Maninder Singh Setia, Tarang Gianchandani
Summary: This study conducted real-life research on healthcare workers in Mumbai, India, and found that full vaccination significantly reduced the rate of infection, especially severe infections. Even among those who were infected, the hospitalization rate was very low and there were no deaths. The effectiveness of the vaccine was higher for those who had previous infection with COVID-19 and completed full vaccination.
Review
Medicine, General & Internal
Rosanna W. Peeling, David L. Heymann, Yik-Ying Teo, Patricia J. Garcia
Summary: Diagnostics play a crucial role in the response to the COVID-19 pandemic. Molecular tests like PCR are recommended for confirming diagnosis in symptomatic individuals, while antigen rapid detection tests have the advantage of being easier to perform with faster results and lower cost. Antibody tests can inform public policy but should not be used as proof of immunity. All three types of tests continue to be important in transitioning from pandemic response to control.
Article
Multidisciplinary Sciences
Aashish Contractor, Shashikala Shivaprakash, Anjali Tiwari, Maninder Singh Setia, Tarang Gianchandani
Summary: The study confirms the effectiveness of COVID-19 vaccines in preventing infection and severe symptoms among healthcare workers in Mumbai, India. Complete vaccination reduces the infection rate, especially during the severe delta wave. Prior infection with COVID-19 and complete vaccination significantly increase the effectiveness of infection prevention.
Article
Immunology
Nhu Ngoc Nguyen, Linda Houhamdi, Van Thuan Hoang, Jeremy Delerce, Lea Delorme, Philippe Colson, Philippe Brouqui, Pierre-Edouard Fournier, Didier Raoult, Philippe Gautret
Summary: The reinfection rate of SARS-CoV-2 is low, and the severity of the first and second episodes of infection is similar. The severity of the second episode of COVID-19 is not higher than that of the first infection, even for patients with antibodies.
EMERGING MICROBES & INFECTIONS
(2022)
Article
Multidisciplinary Sciences
Godwin E. Akpan, Luke Bawo, Maame Amo-Addae, Jallah Kennedy, C. Sanford Wesseh, Faith Whesseh, Peter Adewuyi, Lily Sanvee-Blebo, Joseph Babalola, Himiede W. W. Sesay, Trokon O. Yeabah, Dikena Jackson, Fulton Shannon, Chukwuma David Umeokonkwo, Abraham W. Nyenswah, Jane Macauley, Wilhelmina Jallah
Summary: This study investigated cases of COVID-19 reinfection in Liberia and found 13 reinfection cases during the country's third wave of the outbreak, with the majority occurring in Montserrado County, especially among high clusters and international travelers.
Article
Virology
Carlos A. Dounce-Cuevas, Angelica Flores-Flores, Mariana S. Bazan, Victor Portales-Rivera, Araceli A. Morelos-Ulibarri, Blanca Bazan-Perkins
Summary: COVID-19 infection can lead to a range of symptoms, from asymptomatic cases to severe inflammation with multiorgan damage. The severity of the disease is determined by the patient's immune response and excessive release of inflammatory mediators can result in a cytokine storm. Asthma patients show variable outcomes due to the different immune responses, with Th2 response playing a role in preventing cytokine storms in COVID-19.
Review
Endocrinology & Metabolism
John P. Bilezikian, Neil Binkley, Hector F. De Luca, Angelo Fassio, Anna Maria Formenti, Ghada El-Hajj Fuleihan, Annemieke C. Heijboer, Andrea Giustina
Summary: This work reviews and discusses controversial topics regarding vitamin D, SARS-CoV-2 infection, and COVID-19. The International Conferences Controversies in Vitamin D are workshops that started in 2017 and feature international experts and leaders in the field. The fifth annual conference was held in Stresa, Italy, in September 2021.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Public, Environmental & Occupational Health
John P. A. Ioannidis
Summary: The ratio of COVID-19-attributable deaths versus true COVID-19 deaths depends on various factors and is currently leading to under-counting in some countries while possibly over-counting in others. Caution is needed in attributing deaths in syndemics like COVID-19.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2021)
Review
Immunology
Aisha Fakhroo, Hebah A. AlKhatib, Asmaa A. Al Thani, Hadi M. Yassine
Summary: The COVID-19 pandemic continues to pose a devastating threat to social life and economics, with the rise in active cases attributed to the emergence of new SARS-CoV-2 variants. While reinfection cases worldwide have been limited, most reinfected patients were asymptomatic, and the reasons for reinfection included immunological factors. Vaccines have shown effectiveness in preventing severe illness from different variants.
Article
Medicine, General & Internal
Victoria Hall, Sarah Foulkes, Ferdinando Insalata, Peter Kirwan, Ayoub Saei, Ana Atti, Edgar Wellington, Jameel Khawam, Katie Munro, Michelle Cole, Caio Tranquillini, Andrew Taylor-Kerr, Nipunadi Hettiarachchi, Davina Calbraith, Noshin Sajedi, Iain Milligan, Yrene Themistocleous, Diane Corrigan, Lisa Cromey, Lesley Price, Sally Stewart, Elen de Lacy, Chris Norman, Ezra Linley, Ashley D. Otter, Amanda Semper, Jacqueline Hewson, Silvia D'Arcangelo, Meera Chand, Colin S. Brown, Tim Brooks, Jasmin Islam, Andre Charlett, Susan Hopkins
Summary: This study investigated the duration and effectiveness of immunity among healthcare workers in the United Kingdom. It found that two doses of the BNT162b2 vaccine provided high short-term protection against SARS-CoV-2 infection, but this protection significantly decreased after six months. However, infection-acquired immunity boosted by vaccination remained high, even more than one year after infection.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yeon Joo Jeong, Yu Mi Wi, Hyunjin Park, Jong Eun Lee, Si-Ho Kim, Kyung Soo Lee
Summary: Comprehensive insight into the imaging of COVID-19 has enabled early diagnosis and treatment, with different imaging features and management strategies in different stages. Vaccination has proven effective in reducing the risk of severe infections.
Article
Multidisciplinary Sciences
Ludek Berec, Martin Smid, Lenka Pribylova, Ondrej Majek, Tomas Pavlik, Jiri Jarkovsky, Milan Zajicek, Jakub Weiner, Tamara Barusova, Jan Trnka
Summary: Studies in Czech Republic show that the effectiveness of COVID-19 vaccines declines after 7-8 months, with a decrease in protection against infection, hospitalization, and death. Boosters are found to restore the original vaccine effectiveness, and post-infection immunity also diminishes over time.