Timosaponin derivative YY-23 acts as a non-competitive NMDA receptor antagonist and exerts a rapid antidepressant-like effect in mice

Agmatine enhances antidepressant potency of MK-801 and conventional antidepressants in mice

(2015) Vivian Binder Neis et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effects of Striatal ΔFosB Overexpression and Ketamine on Social Defeat Stress–Induced Anhedonia in Mice

(2014) Rachel J. Donahue et al.   BIOLOGICAL PSYCHIATRY

Burst-firing patterns in the prefrontal cortex underlying the neuronal mechanisms of depression probed by antidepressants

(2014) Fei Guo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Knockout of CXCR5 increases the population of immature neural cells and decreases proliferation in the hippocampal dentate gyrus

(2014) Michael J Stuart et al.   Journal of Neuroinflammation

Anti-depressive activities and biotransformation of timosaponin B-III and its derivatives

(2014) WeiXin Jiang et al.   NATURAL PRODUCT RESEARCH

Glutamate-Based Antidepressants: Preclinical Psychopharmacology

(2013) Andrzej Pilc et al.   BIOLOGICAL PSYCHIATRY

Rapid-Acting Glutamatergic Antidepressants: The Path to Ketamine and Beyond

(2013) John H. Krystal et al.   BIOLOGICAL PSYCHIATRY

Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg2+ and memantine under conditions of agonist exposure

(2013) Sean McKay et al.   NEUROPHARMACOLOGY

Ketamine effects on brain GABA and glutamate levels with 1H-MRS: relationship to ketamine-induced psychopathology

(2012) J M Stone et al.   MOLECULAR PSYCHIATRY

Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents

(2012) Ronald S. Duman et al.   TRENDS IN NEUROSCIENCES

Is There Anything Really Novel on the Antidepressant Horizon?

(2012) James W. Murrough et al.   Current Psychiatry Reports

Ketamine plus imipramine treatment induces antidepressant-like behavior and increases CREB and BDNF protein levels and PKA and PKC phosphorylation in rat brain

(2011) Gislaine Z. Réus et al.   BEHAVIOURAL BRAIN RESEARCH

1H-[13C]-Nuclear Magnetic Resonance Spectroscopy Measures of Ketamine's Effect on Amino Acid Neurotransmitter Metabolism

(2011) Golam M.I. Chowdhury et al.   BIOLOGICAL PSYCHIATRY

A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department

(2011) Gregory Luke Larkin et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

A standardized protocol for repeated social defeat stress in mice

(2011) Sam A Golden et al.   Nature Protocols

A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression

(2010) Nancy Diazgranados et al.   ARCHIVES OF GENERAL PSYCHIATRY

A Review of Current Guidelines for Depression Treatment

(2010) Alan J. Gelenberg   JOURNAL OF CLINICAL PSYCHIATRY

Cracking the moody brain: Lifting the mood with ketamine

(2010) James W Murrough et al.   NATURE MEDICINE

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour

(2009) Sachiko Taniguchi et al.   EMBO JOURNAL

Positive AMPA Receptor Modulation Rapidly Stimulates BDNF Release and Increases Dendritic mRNA Translation

(2009) H. Jourdi et al.   JOURNAL OF NEUROSCIENCE

Potency, voltage-dependency, agonist concentration-dependency, blocking kinetics and partial untrapping of the uncompetitive N-methyl-d-aspartate (NMDA) channel blocker memantine at human NMDA (GluN1/GluN2A) receptors

(2009) Kate E. Gilling et al.   NEUROPHARMACOLOGY

Evaluation of the antipsychotic effect of bi-acetylated l-stepholidine (l-SPD-A), a novel dopamine and serotonin receptor dual ligand

(2009) Yang Guo et al.   SCHIZOPHRENIA RESEARCH

Glutamate-based antidepressants: 20 years on

(2009) Phil Skolnick et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder

(2008) Sheldon H. Preskorn et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

The molecular neurobiology of depression

(2008) Vaishnav Krishnan et al.   NATURE

Major Depressive Disorder

(2008) R.H. Belmaker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Activin in the Brain Modulates Anxiety-Related Behavior and Adult Neurogenesis

(2008) Hiroshi Ageta et al.   PLoS One