Clinical and basic research investigations into the long‐term effects of prenatal opioid exposure on brain development

Regulation of Synaptic Development by Astrocyte Signaling Factors and Their Emerging Roles in Substance Abuse

(2020) Christopher D. Walker et al.   Cells

Microglia Express Mu Opioid Receptor: Insights From Transcriptomics and Fluorescent Reporter Mice

(2019) Tando Maduna et al.   Frontiers in Psychiatry

Brain Differences Between Men and Women: Evidence From Deep Learning

(2019) Jiang Xin et al.   Frontiers in Neuroscience

Prenatal opioid exposure: The next neonatal neuroinflammatory disease

(2019) Lauren L. Jantzie et al.   BRAIN BEHAVIOR AND IMMUNITY

Memory formation depends on both synapse-specific modifications of synaptic strength and cell-specific increases in excitability

(2018) John Lisman et al.   NATURE NEUROSCIENCE

Deleterious effects of prenatal exposure to morphine on the spatial learning and hippocampal BDNF and long-term potentiation in juvenile rats: Beneficial influences of postnatal treadmill exercise and enriched environment

(2018) Ali Ahmadalipour et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Functional MRI in prenatally opioid-exposed children during a working memory-selective attention task

(2018) Eivind Sirnes et al.   NEUROTOXICOLOGY AND TERATOLOGY

Neuroanatomical characteristics of youths with prenatal opioid and poly-drug exposure

(2018) Egil Nygaard et al.   NEUROTOXICOLOGY AND TERATOLOGY

Incidence and Costs of Neonatal Abstinence Syndrome Among Infants With Medicaid: 2004–2014

(2018) Tyler N.A. Winkelman et al.   PEDIATRICS

Expression of kappa opioid receptors in developing rat brain – Implications for perinatal buprenorphine exposure

(2018) Kathleen Z. Tan et al.   REPRODUCTIVE TOXICOLOGY

Expression of µ-Opioid Receptor in CA1 Hippocampal Astrocytes

(2018) Min-Ho Nam et al.   Experimental Neurobiology

Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1

(2018) W. Christopher Risher et al.   JOURNAL OF CELL BIOLOGY

Educational Disabilities Among Children Born With Neonatal Abstinence Syndrome

(2018) Mary-Margaret A. Fill et al.   PEDIATRICS

Oxycodone self-administration during pregnancy disrupts the maternal-infant dyad and decreases midbrain OPRM1 expression during early postnatal development in rats

(2018) Fair M. Vassoler et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Opioid Use Disorder Documented at Delivery Hospitalization — United States, 1999–2014

(2018) Sarah C. Haight et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Capturing the statewide incidence of neonatal abstinence syndrome in real time: the West Virginia experience

(2018) Amna Umer et al.   PEDIATRIC RESEARCH

Mental Disorders Among Children Born With Neonatal Abstinence Syndrome

(2018) Laura J. Sherman et al.   PSYCHIATRIC SERVICES

Opioid system modulators buprenorphine and samidorphan alter behavior and extracellular neurotransmitter concentrations in the Wistar Kyoto rat

(2018) Karen L. Smith et al.   NEUROPHARMACOLOGY

Impact of the opioid system on the reproductive axis

(2017) Bettina Böttcher et al.   FERTILITY AND STERILITY

Mu-opioid receptor and delta-opioid receptor differentially regulate microglial inflammatory response to control proopiomelanocortin neuronal apoptosis in the hypothalamus: effects of neonatal alcohol

(2017) Pallavi Shrivastava et al.   Journal of Neuroinflammation

An Atypical Withdrawal Syndrome in Neonates Prenatally Exposed to Gabapentin and Opioids

(2017) Sean Loudin et al.   JOURNAL OF PEDIATRICS

Rural and Appalachian Disparities in Neonatal Abstinence Syndrome Incidence and Access to Opioid Abuse Treatment

(2017) Joshua D. Brown et al.   JOURNAL OF RURAL HEALTH

The use of brain organoids to investigate neural development and disease

(2017) Elizabeth Di Lullo et al.   NATURE REVIEWS NEUROSCIENCE

Neonatal Abstinence Syndrome and High School Performance

(2017) Ju Lee Oei et al.   PEDIATRICS

Plasma Brain-Derived Neurotrophic Factor Levels in Newborn Infants with Neonatal Abstinence Syndrome

(2017) Lochan Subedi et al.   Frontiers in Pediatrics

Gabapentin misuse, abuse and diversion: a systematic review

(2016) Rachel V. Smith et al.   ADDICTION

How neuroinflammation contributes to neurodegeneration

(2016) R. M. Ransohoff   SCIENCE

Maternal use of methadone and risk of sudden neonatal death

(2015) Marta C. Cohen et al.   ACTA PAEDIATRICA

The Prescription Opioid and Heroin Crisis: A Public Health Approach to an Epidemic of Addiction

(2015) Andrew Kolodny et al.   Annual Review of Public Health

Cognitive function of youths born to mothers with opioid and poly-substance abuse problems during pregnancy

(2015) Egil Nygaard et al.   CHILD NEUROPSYCHOLOGY

Persisting Behavior Problems in Extremely Low Birth Weight Adolescents

(2015) H. Gerry Taylor et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

Increasing incidence and geographic distribution of neonatal abstinence syndrome: United States 2009 to 2012

(2015) S W Patrick et al.   Journal of Perinatology

Effects of environmental enrichment on behavioral deficits and alterations in hippocampal BDNF induced by prenatal exposure to morphine in juvenile rats

(2015) A. Ahmadalipour et al.   NEUROSCIENCE

Prenatal drug exposure to illicit drugs alters working memory-related brain activity and underlying network properties in adolescence

(2015) Julie B. Schweitzer et al.   NEUROTOXICOLOGY AND TERATOLOGY

Longitudinal cognitive development of children born to mothers with opioid and polysubstance use

(2015) Egil Nygaard et al.   PEDIATRIC RESEARCH

Astrocytes Control Synapse Formation, Function, and Elimination

(2015) Won-Suk Chung et al.   Cold Spring Harbor Perspectives in Biology

Role of steroid hormones and morphine treatment in the modulation of opioid receptor gene expression in brain structures in the female rat

(2015) Wesley Soares Cruz et al.   SpringerPlus

Socioeconomic Status and Substance Use Among Young Adults: A Comparison Across Constructs and Drugs

(2015) Megan E. Patrick et al.   Journal of Studies on Alcohol and Drugs

The Opioid System and Brain Development: Effects of Methadone on the Oligodendrocyte Lineage and the Early Stages of Myelination

(2014) Allison A. Vestal-Laborde et al.   DEVELOPMENTAL NEUROSCIENCE

Do maternal opioids reduce neonatal regional brain volumes? A pilot study

(2014) Q Yuan et al.   Journal of Perinatology

Developmental Consequences of Fetal Exposure to Drugs: What We Know and What We Still Must Learn

(2014) Emily J Ross et al.   NEUROPSYCHOPHARMACOLOGY

Neonatal Abstinence Syndrome

(2014) P. Kocherlakota   PEDIATRICS

Acute and Chronic Mu Opioids Differentially Regulate Thrombospondins 1 and 2 Isoforms in Astrocytes

(2013) Ellen Phamduong et al.   ACS Chemical Neuroscience

Adolescent Morphine Exposure Affects Long-Term Microglial Function and Later-Life Relapse Liability in a Model of Addiction

(2013) J. M. Schwarz et al.   JOURNAL OF NEUROSCIENCE

Postnatal maturation of endogenous opioid systems within the periaqueductal grey and spinal dorsal horn of the rat

(2013) Charlie H.T. Kwok et al.   PAIN

Depression-Like Effect of Prenatal Buprenorphine Exposure in Rats

(2013) Chih-Jen Hung et al.   PLoS One

Prenatal buprenorphine exposure decreases neurogenesis in rats

(2013) Chih-Cheng Wu et al.   TOXICOLOGY LETTERS

Gabapentinoid Abuse in Order to Potentiate the Effect of Methadone: A Survey among Substance Misusers

(2013) Colin R.W. Baird et al.   EUROPEAN ADDICTION RESEARCH

Opioid receptor expression in human brain and peripheral tissues using absolute quantitative real-time RT-PCR

(2012) Jinsong Peng et al.   DRUG AND ALCOHOL DEPENDENCE

The “quad-partite” synapse: Microglia-synapse interactions in the developing and mature CNS

(2012) Dorothy P. Schafer et al.   GLIA

Neonatal Abstinence Syndrome and Associated Health Care Expenditures

(2012) Stephen W. Patrick et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Endogenous opioid systems: Current concepts and clinical correlations

(2012) E. E. Benarroch   NEUROLOGY

Effects of prenatal cocaine and heroin exposure on neuronal dendrite morphogenesis and spatial recognition memory in mice

(2012) Ruhui Lu et al.   NEUROSCIENCE LETTERS

Neonatal Drug Withdrawal

(2012) M. L. Hudak et al.   PEDIATRICS

Accelerated myelination with motor system involvement in a neonate with immediate postnatal onset of seizures and hemimegalencephaly

(2011) Grant Goldsberry et al.   EPILEPSY & BEHAVIOR

Oligodendrocyte responses to buprenorphine uncover novel and opposing roles of μ-opioid- and nociceptin/orphanin FQ receptors in cell development: Implications for drug addiction treatment during pregnancy

(2011) Andrew C. Eschenroeder et al.   GLIA

Prenatal exposure to methadone HCL in relationship to body and brain growth in the rat

(2010) Donald H. Ford et al.   ACTA NEUROLOGICA SCANDINAVICA

Alterations in brain structure and functional connectivity in prescription opioid-dependent patients

(2010) J. Upadhyay et al.   BRAIN

Brain-derived neurotrophic factor and the development of structural neuronal connectivity

(2010) Susana Cohen-Cory et al.   Developmental Neurobiology

Changes in adaptability following perinatal morphine exposure in juvenile and adult rats

(2010) Barbara Klausz et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Morphine Modulation of Thrombospondin Levels in Astrocytes and Its Implications for Neurite Outgrowth and Synapse Formation

(2010) Hiroko Ikeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BDNF upregulation rescues synaptic plasticity in middle-aged ovariectomized rats

(2010) Enikö A. Kramár et al.   NEUROBIOLOGY OF AGING

Infant Neurobehavior Following Prenatal Exposure to Methadone or Buprenorphine: Results From the Neonatal Intensive Care Unit Network Neurobehavioral Scale

(2010) Hendrée E. Jones et al.   SUBSTANCE USE & MISUSE

Gray matter density negatively correlates with duration of heroin use in young lifetime heroin-dependent individuals

(2009) Yi Yuan et al.   BRAIN AND COGNITION

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

(2009) Çagla Eroglu et al.   CELL

Prenatal exposure to heroin in mice elicits memory deficits that can be attributed to neuronal apoptosis

(2009) Y. Wang et al.   NEUROSCIENCE

Opioid addiction and pregnancy: Perinatal exposure to buprenorphine affects myelination in the developing brain

(2008) Emilse S. Sanchez et al.   GLIA

Prenatal Morphine Exposure Attenuates the Maintenance of Late LTP in Lateral Perforant Path Projections to the Dentate Gyrus and the CA3 Region In Vivo

(2008) D. M. Villarreal et al.   JOURNAL OF NEUROPHYSIOLOGY

Opioidergic and dopaminergic modulation of respiration

(2008) Peter M. Lalley   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY