Article
Chemistry, Multidisciplinary
Yi Qiu, Zhuoqi Wen, Shiliang Mei, Jinxin Wei, Yuanyuan Chen, Zhe Hu, Zhongjie Cui, Wanlu Zhang, Fengxian Xie, Ruiqian Guo
Summary: In this study, stabilized Cu NCs powder was obtained using cation crosslinking method, which significantly enhanced the stability compared to solvent precipitation method. The binding of Ce3+ with the capping ligands of Cu NCs formed a compact structure, leading to long-lasting fluorescence and unchanged physical form, showing great potential in various applications.
Article
Chemistry, Applied
Pushpendra, Indranil Suryawanshi, Rimple Kalia, Ravi K. Kunchala, Shyam Lal Mudavath, Boddu S. Naidu
Summary: This study reports the use of Gd0.95Eu0.05PO4 nanorods for latent fingerprint visualization under 395 nm light. The nanorods exhibit excellent photoluminescence properties and strong fuchsia emission. They have been successfully employed for developing clear and well-defined latent fingerprints on various substrates.
JOURNAL OF RARE EARTHS
(2022)
Article
Chemistry, Inorganic & Nuclear
Takenori Dairaku, Rika Kawai, Teppei Kanaba, Tetsuya Ono, Kentaro Yoshida, Hajime Sato, Kanako Nozawa-Kumada, Yoshinori Kondo, Jiro Kondo, Akira Ono, Yoshiyuki Tanaka, Yoshitomo Kashiwagi
Summary: The study revealed that Ag+-mediated base pairing lowers the redox potential of the Ag+/Ag couple, making it more difficult to reduce captured Ag+ ions. The cytidine/Ag+ system can be utilized to control the redox potential of the Ag+/Ag couple in DMSO, which may be exploited for Ag nanoparticle synthesis.
DALTON TRANSACTIONS
(2021)
Article
Polymer Science
Gabriela Broncova, Tereza Slaninova, Miroslava Trchova, Vadim Prokopec, Pavel Matejka, Tatiana Shishkanova
Summary: This study focused on the visualization of latent fingerprints on brass surfaces using electrochemical deposition of a polymer film based on poly(neutral red) (PNR). Experimental findings showed that this method is a significant advancement in the field and offers a new approach for criminalists in combating crime.
Article
Nanoscience & Nanotechnology
Hanbin Xu, Huan Liang, Jing Zheng, Guobao Ning, Li Wang, Jing Zeng, Hui Zhao, Can-Peng Li
Summary: By synthesizing CsPbBr3/Cs4PbBr6 nanostructured composite crystals, high-quality visualization of latent fingerprints has been achieved; the composite crystals exhibit excellent environmental and water stability, enabling clear fingerprint image display on various surfaces; these perovskite nanocrystals have the potential to serve as stable and brightly luminescent labeling agents for crime scene and personal identifications.
Article
Biophysics
Huinan Chen, Yuanyuan Li, Yuchen Song, Fujing Liu, Dongmei Deng, Xiaoli Zhu, Haibo He, Xiaoxia Yan, Liqiang Luo
Summary: In this research, an innovative sandwich-type electrochemical immunosensor is designed for the ultrasensitive determination of tumor biomarker AFP using spherical nucleic acids-templated silver nanoclusters (AgNCs) sensing platform. The immunosensor exhibits broad linearity range and low detection limit, providing a novel method for sensitive clinical diagnosis of tumor markers in human hepatocellular carcinoma.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Nanoscience & Nanotechnology
Zhinan Fan, Chi Zhang, Jiajun Chen, Rongliang Ma, Yaoqi Lu, Jia-Wei Wu, Li-Juan Fan
Summary: The study demonstrates a simple and effective strategy for visualizing LBFPs, showing clear fingerprint patterns and details even on challenging substrates. The method exhibits superior stability over long-term storage and against solvent washing, while maintaining the integrity of DNA.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Analytical
Minglu Li, Peng Lei, Shengmei Song, Shaomin Shuang, Ruibing Wang, Chuan Dong
Summary: The study used the butterfly-shaped molecule DPTS with solid fluorescence and ESIPT properties to enhance the visualization of latent fingerprints, showing promising results. DPTS fluorescence color and efficiency can be tuned by changing the morphology of its aggregates, demonstrating good detection of LFPs and high specificity in living cells.
Article
Electrochemistry
Gabriela Broncova, Tereza Slaninova, Miroslava Trchova
Summary: This study demonstrates the characterization of electrochemically visualized latent fingerprints on steel surfaces. By optimizing the electrochemical conditions and visualization parameters, visible fingerprints on steel substrates were successfully obtained. The experimental findings show that latent fingerprint visualization is a simple, fast, efficient, and inexpensive method applicable to forensic evidence.
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
(2022)
Article
Polymer Science
Jinyu Yang, Yayang Wang, Yuan Zhao, Dongliang Liu, Lu Rao, Zhijun Wang, Lili Fu, Yifan Wang, Xiaojie Yang, Yuesheng Li, Yi Liu
Summary: In this study, an Ag/CMCS/PVA hydrogel film for fingerprint development was developed using the electron beam radiation method. The optimal preparation conditions were determined through experimental exploration. This research has important scientific significance for the development of new processes and functional materials in the field of fingerprint manifestation.
Article
Chemistry, Analytical
Ying Zhao, Hao Zhang, Lili Lian, Xiyue Wang, Wenxiu Gao, Bo Zhu, Dawei Lou
Summary: A low-cost silver nanocluster fluorescent sensor with a DNA template was developed in this study, which detects target DNA using a hairpin DNA sequence and shows a strong relationship between fluorescence intensity and target DNA concentration.
ANALYTICAL SCIENCES
(2022)
Article
Virology
Angela N. H. Creager
Summary: This article reviews the history of research on tobacco mosaic virus (TMV), highlighting its close connections to the emergence and development of molecular biology.
ANNUAL REVIEW OF VIROLOGY
(2022)
Article
Nanoscience & Nanotechnology
Zhenhua Li, Zhenzhen Wang, Phuong-Uyen C. Dinh, Dashuai Zhu, Kristen D. Popowski, Halle Lutz, Shiqi Hu, Mark G. Lewis, Anthony Cook, Hanne Andersen, Jack Greenhouse, Laurent Pessaint, Leonard J. Lobo, Ke Cheng
Summary: The authors demonstrate that nanovesicles coated with lung spheroid cell membranes expressing angiotensin-converting enzyme 2 can bind and neutralize SARS-CoV-2, potentially serving as a therapeutic agent for treating COVID-19.
NATURE NANOTECHNOLOGY
(2021)
Article
Engineering, Biomedical
Mengjie Xie, Junlang Li, Sichen Zhang, Dashuai Zhu, Xuan Mei, Zhenzhen Wang, Xiao Cheng, Zhenhua Li, Shaowei Wang, Ke Cheng
Summary: The newly developed TGN contraceptive gel showed high efficacy in preventing pregnancy and displayed a strong spermicidal effect in vitro. In addition, it significantly inhibited viral transfection and enhanced male sexual function in animal experiments. These promising results suggest great potential for further translation and commercialization of this multifunctional gel.
BIOACTIVE MATERIALS
(2021)
Article
Biotechnology & Applied Microbiology
Chi Zhang, Wei Zhang, Dashuai Zhu, Zhenhua Li, Zhenzhen Wang, Junlang Li, Xuan Mei, Wei Xu, Ke Cheng, Biao Zhong
Summary: This study proposes a method using cell-mimicking and targeted therapeutic nanoparticles to replace stem cells. The results show that in a rat model of osteoporosis, this treatment can accumulate in bone, inhibit osteoclast differentiation, and promote osteogenic proliferation. Additionally, this treatment reduces bone mass attenuation in rats with ovariectomy-induced bone loss.
JOURNAL OF NANOBIOTECHNOLOGY
(2022)
Review
Chemistry, Inorganic & Nuclear
Fang Pu, Jinsong Ren, Xiaogang Qu
Summary: Sensor arrays based on nucleic acids have great potential in detecting multiple targets. However, there is a lack of comprehensive reviews on sensor arrays from the perspective of nucleic acid as sensing elements.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Multidisciplinary Sciences
Yawen You, Qingqing Deng, Yibo Wang, Yanjuan Sang, Guangming Li, Fang Pu, Jinsong Ren, Xiaogang Qu
Summary: This study reports on a DNA-based biocompatible, highly efficient, and precisely targeted copper nanocatalyst, which exhibits excellent catalytic activity and achieves efficient prodrug activation and antitumor effects in cancer cells.
NATURE COMMUNICATIONS
(2022)
Correction
Multidisciplinary Sciences
Yawen You, Qingqing Deng, Yibo Wang, Yanjuan Sang, Guangming Li, Fang Pu, Jinsong Ren, Xiaogang Qu
NATURE COMMUNICATIONS
(2022)
Article
Engineering, Biomedical
Zhenzhen Wang, Kristen D. Popowski, Dashuai Zhu, Blanca Lopez de Juan Abad, Xianyun Wang, Mengrui Liu, Halle Lutz, Nicole De Naeyer, C. Todd DeMarco, Thomas N. Denny, Phuong-Uyen C. Dinh, Zhenhua Li, Ke Cheng
Summary: Researchers have developed an inhalable and room-temperature-stable virus-like particle COVID-19 vaccine that induces systemic and mucosal immune responses in small animals. The vaccine, consisting of a recombinant SARS-CoV-2 receptor-binding domain conjugated to lung-derived exosomes, enhanced the retention of the receptor-binding domain in the respiratory airway and lungs, and cleared SARS-CoV-2 pseudovirus in mice. In hamsters, the vaccine attenuated severe pneumonia and reduced inflammatory infiltrates after a challenge with live SARS-CoV-2.
NATURE BIOMEDICAL ENGINEERING
(2022)
Article
Cardiac & Cardiovascular Systems
Dashuai Zhu, Shuo Liu, Ke Huang, Zhenzhen Wang, Shiqi Hu, Junlang Li, Zhenhua Li, Ke Cheng
Summary: This study reveals that the pericardial drainage pathway promotes immune activation in the mediastinal lymph node following myocardial infarction, and MSC exosomes induce regulatory T cell differentiation through the Foxo3 pathway to promote cardiac repair.
CIRCULATION RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Jiawei Zhu, Yawen You, Wenting Zhang, Fang Pu, Jinsong Ren, Xiaogang Qu
Summary: In order to boost the endogenous Cu(I) level for intracellular drug synthesis through the bioorthogonal reaction, a self-adaptive bioorthogonal catalysis system was constructed by encapsulating prodrugs and sodium ascorbate within adenosine triphosphate aptamer-functionalized metal-organic framework nanoparticles. The system presents specificity to tumor cells and does not require exogenous Cu catalysts, thereby leading to high anti-tumor efficacy and minimal side effects both in vitro and in vivo. This work will open up a new opportunity for developing biosafe and high-performance bioorthogonal catalysis systems.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Guangming Li, Hao Liu, Jiadai Yi, Fang Pu, Jinsong Ren, Xiaogang Qu
Summary: A versatile fiber-based compartmentalization strategy is developed to construct multi-nanozyme system capable of simultaneously performing incompatible reactions. Different microenvironments are tailored to each nanozyme, allowing them to exhibit their highest activity. This strategy has potential applications in disease treatment and biosensing.
Article
Chemistry, Multidisciplinary
Minhao Jiang, Xiangyu Yan, Yibo Wang, Fang Pu, Huiling Liu, Yumei Li, Chunfeng Yang, Jiawei Zhu, Xuemeng Liu, Jinsong Ren, Xiaogang Qu
Summary: A one-component sensor array that mimics natural gustatory system is constructed for accurate and high-throughput discrimination and identification of versatile analytes. The system shows universality by rapidly and accurately discriminating metal ions, proteins, bacteria, and classifying antibiotic mechanisms. This study expands the application scope of HOFs and provides a facile and universal system for sensing applications.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Physical
Xuan Mei, Junlang Li, Zhenzhen Wang, Dashuai Zhu, Ke Huang, Shiqi Hu, Kristen D. Popowski, Ke Cheng
Summary: Researchers developed an inhalable bioadhesive hydrogel called SHIELD, which forms a dense hydrogel layer in the airway to enhance barrier properties against SARS-CoV-2 infection. The method was shown to effectively protect against SARS-CoV-2 virus variants in mice and non-human primates.
Article
Multidisciplinary Sciences
Zhenzhen Wang, Zhenhua Li, Weiwei Shi, Dashuai Zhu, Shiqi Hu, Phuong-Uyen C. Dinh, Ke Cheng
Summary: The combination of SARS-CoV-2 virus-like particle (VLP) vaccine with inactivated influenza A virus provides protection against COVID-19, influenza, and co-infection, inducing strong immune responses and neutralization activity.
Article
Chemistry, Multidisciplinary
Yawen You, Hao Liu, Jiawei Zhu, Yibo Wang, Fang Pu, Jinsong Ren, Xiaogang Qu
Summary: This study developed a DNAzyme-augmented and targeted bioorthogonal catalyst that exhibits specificity to cancer cells and promotes the generation of Cu(i) for in situ drug synthesis. The DNAzyme also damages cancer cells, resulting in synergistic cancer therapy.
Article
Chemistry, Multidisciplinary
Xiang Ran, Zhenzhen Wang, Fang Pu, Enguo Ju, Jinsong Ren, Xiaogang Qu
Summary: A novel probe based on Au nanoclusters with aggregation-induced emission property was developed for sensitive telomerase detection in living cells and solid tumor tissue. This study provided insight into the specific connection mechanism of metal nanoclusters for AIE generation and shows great potential for disease detection both in vitro and in vivo.
MATERIALS HORIZONS
(2021)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)