Article
Anesthesiology
Kyle J. Morgan, Rahul Mohan, Seth E. Karol, Jamie Flerlage
Summary: Many anaesthetists are hesitant to perform epidural blood patch in patients with cancer due to the potential risk of spreading malignant cells to the central nervous system. Recent evidence suggests that malignancy may be viewed as a relative rather than absolute contraindication to this procedure.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Article
Emergency Medicine
Juho An, Sung-Eun Lee, Yura Ko, Heewon Yang
Summary: This study aimed to investigate the association between traumatic tap and the incidence of postdural puncture headache (PDPH) following lumbar puncture (LP) among patients who underwent LP with a primary discharge diagnosis of primary headache in the emergency department (ED). The results showed that among patients who underwent emergency department lumbar puncture, 34.8% reported PDPH and 35.7% required hospitalization. Furthermore, there were significant differences in the hospitalization rate and incidence of PDPH between patients with traumatic LP and those with primary headaches.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2023)
Article
Emergency Medicine
Matthew D. Monaco, Levi K. Kitchen, Robert L. Frank, Kenneth D. McManus
Summary: Acute headache is a common chief complaint in the emergency department which may have serious underlying conditions like subarachnoid hemorrhage (SAH). With advancements in computed tomography (CT), CT angiography is now being used to rule out SAH.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Medicine, General & Internal
Chien-Shu Tai, Shang-Liang Wu, Shao-Yu Lin, Ying Liang, Shuu-Jiun Wang, Shih-Pin Chen
Summary: The study found that bed rest following lumbar puncture does not prevent PDPH and might even slightly increase the risk of PDPH. This suggests a need for amending the current post-lumbar puncture care guidelines to improve patient outcomes.
JOURNAL OF THE CHINESE MEDICAL ASSOCIATION
(2021)
Article
Anesthesiology
Jessica R. Ansari, Meredith Barad, Steven Shafer, Pamela Flood
Summary: The study found that women who experienced unintentional dural puncture had a higher prevalence of chronic disabling headache at 2 and 6 months postpartum, but there was no significant difference in back pain prevalence.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Review
Clinical Neurology
Meredith Barad, Ian Carroll, Miguel A. Reina, Jessica Ansari, Pamela Flood
Summary: In postpartum women who have undergone unintended dural puncture with a large bore needle for epidural catheter placement, the rate of chronic debilitating headache is around 30% in the months following delivery and may persist for up to a year or longer. This highlights the need for further research and diagnosis to better understand and manage the long-term impact of postdural puncture headache.
Article
Medicine, General & Internal
Melissandre Nicot, Ludovic Miraillet, Bruno Pereira, Jean-Baptiste Bouillon-Minois, Julien Raconnat, Fares Moustafa, Jeannot Schmidt, Sophia Sickout-Arondo, Lise Bernard, Pierre Clavelou, Xavier Moisset
Summary: The study showed that inhalation of a fixed 50% nitrous oxide-oxygen mixture did not reduce the pain caused by lumbar puncture in an emergency setting, but it did help to reduce anxiety and significantly increase patient satisfaction.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Anesthesiology
Andre P. Boezaart, Cameron R. Smith, Yury Zasimovich, Rene Przkora, Sanjeev Kumar, Olga C. Nin, Louis C. Boezaart, Daniel A. J. Botha, Andre Leonard, Miguel A. Reina, Juan A. Pareja
Summary: In 1981, Devoghel achieved a high success rate in treating patients with treatment-refractory cluster headaches by alcoholization of the PPG. This led to the theory that blocking the PPG could prevent or treat symptoms related to PHDs. Furthermore, nVNS has been proven effective in treating PHDs and has regulatory approval for cluster headaches and migraines. Nine patients with treatment-refractory primary headache disorders and PDPH received PPGB and nVNS, resulting in immediate and lasting symptom resolution.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Medicine, General & Internal
Ross Cody, Mahsa Mohsenifard, Gary Yip, Emogene Aldridge, Francesca Bridge, Mineesh Datta, Stephen Guy, Peter Jordan, Chris Kyndt, Evan Newnham, Mark Ng, Elizabeth Paul, Owen Roodenburg, Channa Senanayake, Sarah Sparham, Michelle Steele, Helen Dewey
Summary: Lumbar puncture is a valuable diagnostic procedure in the Australian setting, with a high diagnostic yield and a low rate of major complications. The most common complication is post-dural puncture headache, which is self-limiting in most cases.
INTERNAL MEDICINE JOURNAL
(2023)
Article
Multidisciplinary Sciences
Isao Utsumi, Tomasz Hascilowicz, Sachiko Omi
Summary: The study confirmed the subjective sensation of click when puncturing the dura-arachnoid with different types of spinal needles, indicating that click recognition could serve as an additional indicator of successful spinal puncture. Both subjective and objective evaluations demonstrated that participants could distinguish among needles of different tip shapes, and subjective numerical rating scale values corresponded well with objectively measured changes in force.
Article
Pediatrics
David C. Schorling, Astrid Pechmann, Matthias Eckenweiler, Cornelia K. Mueller, Thorsten Langer, Janbernd Kirschner
Summary: This study found that the prevalence of PDPH after therapeutic LPs in SMA patients was significantly lower than in general pediatric patients. The overall prevalence of PDPH in pediatric patients was similar to that reported in larger adult cohorts.
Article
Anesthesiology
Alexandre Lacombe, Kristi Downey, Xiang Y. Ye, Jose C. A. Carvalho
Summary: Unintentional dural puncture during epidural catheter insertion in parturients is associated with increased risk of chronic headache, back pain, and auditory impairment.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2022)
Article
Emergency Medicine
Emmanuel Cognat, Berengere Koehl, Matthieu Lilamand, Stephane Goutagny, Anissa Belbachir, Louise de Charentenay, Tamazoust Guiddir, Paul Zetlaoui, Caroline Roos, Claire Paquet
Summary: Older age, female sex, lower body mass index, and history of headache may increase the risk of post-lumbar puncture headache. The use of atraumatic, noncutting needles is the most effective intervention for prevention, while other measures seem to have limited impact.
ANNALS OF EMERGENCY MEDICINE
(2021)
Article
Medicine, General & Internal
Yin Zhou, Zhiyu Geng, Linlin Song, Dongxin Wang
Summary: This study evaluated the role of hydroxyethyl starch (HES) in preventing postdural puncture headache (PDPH) after accidental dural puncture (ADP) during obstetric epidural procedures. It found that the incorporated prophylactic strategy, including epidural catheter re-siting, continuous epidural analgesia, and two doses of epidural HES, was associated with a significant decrease in the risk of PDPH, and no neurological deficits were reported.
CHINESE MEDICAL JOURNAL
(2023)
Article
Clinical Neurology
Jasem Al-Hashel, Azza Rady, Fathi Massoud, Ismail Ibrahim Ismail
Summary: This study aimed to investigate the incidence, risk factors, and clinical characteristics of post-dural puncture headache (PDPH) in patients admitted to a main tertiary neurology hospital in Kuwait. The results showed that younger age, female gender, lower BMI, pre-procedural headache, history of previous PDPH, and number of lumbar puncture attempts were identified as independent risk factors for developing PDPH.
Article
Anesthesiology
Camilo Toro, Sonia Jain, Shelly Sun, Nancy Temkin, Jason Barber, Geoffrey M. Manley, Jordan M. Komisarow, Tetsu Ohnuma, Brandon Foreman, Frederick L. Korley, Michael L. James, Daniel S. Laskowitz, Monica S. Vavilala, Adrian P. Hernandez, Joseph P. J. Mathew, Amy J. Markowitz, Vijay Krishnamoorthy
Summary: This retrospective cohort study assessed the impact of brain injury biomarkers on the risk of circulatory shock in patients with moderate-severe traumatic brain injury. The study found an association between the levels of neuronal injury biomarkers and the development of circulatory shock. The results suggest that neuronal injury biomarkers may provide early identification of patients at risk for early circulatory shock following TBI.
JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Maham F. Karatela, Marat Fudim, Joseph P. Mathew, Jonathan P. Piccini
Summary: Atrial fibrillation is influenced by both sympathetic and parasympathetic influences through cardiac autonomic innervation. Innovative therapies targeting the neurocardiac axis, such as catheter ablation or pharmacologic suppression of ganglionated plexi, renal sympathetic denervation, low-level vagal stimulation, and stellate ganglion blockade, have variable efficacy. Improving our understanding of atrial fibrillation and the cardiac nervous system will lead to further advancements in therapeutic neuromodulation for the benefit of patients with AF.
Article
Surgery
Ander Dorken-Gallastegi, Angela M. Renne, Mary Bokenkamp, Dias Argandykov, Anthony Gebran, Jefferson A. Proano-Zamudio, Jonathan J. Parks, John O. Hwabejire, George C. Velmahos, Haytham M. A. Kaafarani
Summary: The association between balanced blood component transfusion and lower mortality is not generalizable to trauma patients with different transfusion volumes. Red blood cell transfusion volume plays a role in the relationship between red blood cell:platelet and red blood cell:fresh frozen plasma ratios and 4-hour mortality. The association is less evident in patients receiving lower volumes of red blood cells.
Article
Emergency Medicine
Lorenzo Cobianchi, Daniele Piccolo, Francesca Dal Mas, Vanni Agnoletti, Luca Ansaloni, Jeremy Balch, Walter Biff, Giovanni Butturini, Fausto Catena, Federico Coccolini, Stefano Denicolai, Belinda De Simone, Isabella Frigerio, Paola Fugazzola, Gianluigi Marseglia, Giuseppe Roberto Marseglia, Jacopo Martellucci, Mirko Modenese, Pietro Previtali, Federico Ruta, Alessandro Venturi, Haytham M. Kaafarani, Tyler J. Loftus
Summary: This study investigates trauma and emergency surgeons' knowledge and perception of using AI-based tools in clinical decision-making processes. The results show that there are technology enthusiasts and skeptics among surgeons, with a preference towards more classical decision-making aids. Lack of knowledge about AI and mistrust are also observed.
WORLD JOURNAL OF EMERGENCY SURGERY
(2023)
Article
Oncology
Hannah E. Dzimitrowicz, Lauren E. Wilson, Bradford E. Jackson, Lisa P. Spees, Christopher D. Baggett, Melissa A. Greiner, Deborah R. Kaye, Tian Zhang, Daniel George, Charles D. Scales, Jessica E. Pritchard, Michael S. Leapman, Cary P. Gross, Michaela A. Dinan, Stephanie B. Wheeler
Summary: OAAs have improved outcomes for patients with metastatic renal cell carcinoma, but little is known about end-of-life care and systemic therapy use in these patients.
JCO ONCOLOGY PRACTICE
(2023)
Article
Oncology
Deborah R. Kaye, Hui-Jie Lee, Alexander Gordee, Daniel J. George, Peter A. Ubel, Charles D. Scales, M. Kate Bundorf
Summary: This study examined the gross and out-of-pocket payments for first-line drugs for metastatic castrate-resistant prostate cancer (mCRPC). The results showed significant variation in gross payments across different drugs, while out-of-pocket payments were relatively low and varied widely.
JCO ONCOLOGY PRACTICE
(2023)
Correction
Anesthesiology
Jeffrey N. Browndyke, Mary C. Wright, Rosa Yang, Ayesha Syed, John Park, Ashley Hall, Katherine Martucci, Michael J. Devinney, Leslie Shaw, Teresa Waligorska, Eugene W. Moretti, Heather E. Whitson, Harvey J. Cohen, Joseph P. Mathew, Miles Berger
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Letter
Anesthesiology
Christopher D. Lascola, Sarah F. Cotter, Rebecca Y. Klinger, Tiffany Bisanar, Mary Cooter Wright, Miles Berger, Gavin Martin, Mihai V. Podgoreanu, Mark F. Newman, Niccolo Terrando, Joseph P. Mathew
JOURNAL OF CLINICAL ANESTHESIA
(2023)
Article
Emergency Medicine
Lorenzo Cobianchi, Francesca Dal Mas, Vanni Agnoletti, Luca Ansaloni, Walter Biffl, Giovanni Butturini, Stefano Campostrini, Fausto Catena, Stefano Denicolai, Paola Fugazzola, Jacopo Martellucci, Maurizio Massaro, Pietro Previtali, Federico Ruta, Alessandro Venturi, Sarah Woltz, Haytham M. Kaafarani, Tyler J. Loftus, Team Dynamics Study Grp
Summary: This study explores the understanding, barriers, and facilitators of shared decision-making (SDM) in trauma and emergency surgery. Findings show that less than half of the surgeons understand SDM and 30% still see value in exclusively engaging multidisciplinary provider teams without involving the patient. The inclusion of SDM practices in clinical guidelines is recommended.
WORLD JOURNAL OF EMERGENCY SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Kamrouz Ghadimi, Jhaymie L. Cappiello, Mary Cooter Wright, Jerrold H. Levy, Benjamin S. Bryner, Adam D. Devore, Jacob N. Schroder, Chetan B. Patel, Sudarshan Rajagopal, Svati H. Shah, Carmelo A. Milano
Summary: In patients undergoing major cardiac surgery for advanced heart failure, inhaled pulmonary-selective vasodilator treatment using iEPO was associated with similar risks for RVF development and development of other postoperative secondary outcomes compared with treatment using iNO.
Article
Anesthesiology
Andre F. Gosling, Mary C. Wright, Anne Cherry, Carmelo A. Milano, Chetan B. Patel, Jacob N. Schroder, Adam DeVore, Sharon McCartney, Daryl Kerr, Benjamin Bryner, Mihai Podgoreanu, Alina Nicoara
Summary: The findings suggest that recipient administration of a single dose of thyroid hormone may not prevent the development of primary graft dysfunction (PGD) after orthotopic heart transplantation, but it may attenuate the severity of PGD.
JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
(2023)
Article
Clinical Neurology
Mario Torso, Gerard R. Ridgway, Michele Valotti, Ian Hardingham, Steven A. Chance
Summary: This study aimed to investigate the associations between cortical diffusion imaging and post-mortem neuropathology of Alzheimer's disease (AD). The results showed significant associations between cortical diffusivity measures and AD neuropathological hallmarks. The study also highlighted the impact of co-pathologies on cortical microstructure, emphasizing the importance of recognizing these factors in diagnosis and treatment decision-making.
ALZHEIMERS RESEARCH & THERAPY
(2023)
Article
Genetics & Heredity
Konstantin G. Arbeev, Svetlana Ukraintseva, Olivia Bagley, Hongzhe Duan, Deqing Wu, Igor Akushevich, Eric Stallard, Alexander Kulminski, Kaare Christensen, Mary F. Feitosa, Jeffrey R. O'Connell, Daniel Parker, Heather Whitson, Anatoliy I. Yashin
Summary: Dysregulation of physiological processes may contribute to the development of Alzheimer's disease, and genes associated with an increase in physiological dysregulation may play a major role in AD onset.
FRONTIERS IN GENETICS
(2023)