Journal
CHEMICAL COMMUNICATIONS
Volume 52, Issue 17, Pages 3568-3571Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc10486f
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Funding
- National Natural Science Foundation of China [21190040, 21175035, 21375034]
- International Science & Technology Cooperation Program of China [2010DFB30300]
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High affinity DNA aptamers against C-reactive protein (CRP) were obtained using a microfluidic chip. The aptamers were then used for the construction of an Au nanoparticle enhanced surface plasmon resonance biosensor, which was introduced for the detection of CRP at concentrations ranging from 10 pM to 100 nM in diluted human serum.
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