Review
Health Care Sciences & Services
Inge van Loenen, Willemijn Scholten, Anna Muntingh, Johannes Smit, Neeltje Batelaan
Summary: The study aims to evaluate the efficacy of virtual reality exposure-based cognitive behavioral therapy (VRE-CBT) in treating more severe anxiety disorders. The meta-analysis results show that VRE-CBT is significantly more effective than waitlist and comparable to regular CBT. The efficacy varies according to the type of anxiety disorder, recruitment method, and type of VRE-CBT. The dropout rates between VRE-CBT and CBT are not significantly different.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Psychiatry
Bokyoung Shin, Jooyoung Oh, Byung-Hoon Kim, Hesun Erin Kim, Hyunji Kim, Suji Kim, Jae-Jin Kim
Summary: This study investigated the potential of self-guided VR as an alternative to high-cost treatment for panic disorder. The mobile app-based VR intervention was effective in treating panic symptoms and restoring the autonomic nervous system, demonstrating the validity and cost-effectiveness of VR treatment.
JMIR MENTAL HEALTH
(2021)
Article
Health Care Sciences & Services
Jordi Piera-Jimenez, Anne Etzelmueller, Spyros Kolovos, Frans Folkvord, Francisco Lupianez-Villanueva
Summary: The study assessed the cost-effectiveness of implementing an internet-based cognitive behavioral therapy intervention for treating major depressive disorder, which was found to be more costly than usual care but cost-effective compared to the willingness-to-pay threshold typically applied in Spain.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Health Care Sciences & Services
Kayoko Taguchi, Noriko Numata, Rieko Takanashi, Ryo Takemura, Tokiko Yoshida, Kana Kutsuzawa, Kensuke Yoshimura, Natsuko Nozaki-Taguchi, Seiji Ohtori, Eiji Shimizu
Summary: This study aimed to examine the effectiveness of an integrated cognitive behavioral therapy program with new components delivered via videoconferencing. The results showed that while it did not reduce pain intensity, it did decrease pain interference and was cost-effective.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Health Care Sciences & Services
Yiwen Wu, Xin Li, Yuxin Zhou, Rui Gao, Kaifeng Wang, Huiling Ye, Na Lyu, Chun Wang, Ning Zhang, Zhen Wang, Qing Fan
Summary: This study compares the efficacy and cost-effectiveness of internet-based cognitive behavioral therapy (ICBT) combined with medication, face-to-face cognitive behavioral group therapy (CBGT) combined with medication, and conventional medical treatment for adults with obsessive-compulsive disorder (OCD). The results show that ICBT combined with medication is as effective as CBGT combined with medication for treating OCD and is more cost-effective.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Review
Psychiatry
Jinlong Wu, Yi Sun, Gongwei Zhang, Zhenhui Zhou, Zhanbing Ren
Summary: This study aimed to investigate the effectiveness of virtual reality-assisted cognitive behavioral therapy (VRCBT) in treating anxiety and depression in patients with anxiety disorders. The results showed that VRCBT had better therapeutic effects on anxiety and depression compared to the waiting list group, and similar effects to standard CBT. The comparison of withdrawal rates between VRCBT and CBT did not reach statistical significance.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Geriatrics & Gerontology
Kai Yeung, Weiwei Zhu, Susan M. McCurry, Michael Von Korff, Robert Wellman, Charles M. Morin, Michael V. Vitiello
Summary: Telephone-delivered CBT-I has been found to improve sleep and arthritis function in older adults with comorbid OA without increasing costs. The study suggests the consideration of this intervention for treating insomnia among older adults with comorbid OA. It also highlights potential limitations of general quality of life measures in assessing interventions designed to improve sleep and arthritis outcomes.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2022)
Article
Medicine, General & Internal
Hyu Seok Jeong, Jee Hyun Lee, Hesun Erin Kim, Jae-Jin Kim
Summary: The study suggests that short-term VR-based individual CBT with nine to ten sessions may be effective for improving social anxiety disorder. Early termination group showed significant improvement, while simply extending the sessions did not lead to significant symptom reduction. This highlights the potential efficacy of even shorter sessions in treating SAD.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Yolanda Alvarez-Perez, Francisco Rivero, Manuel Herrero, Conrado Vina, Ascension Fumero, Moises Betancort, Wenceslao Penate
Summary: The study found that treating 30 patients with specific phobias to small animals using CBT + VRET could significantly reduce anxiety and phobia levels, which were maintained during the follow-up period. Despite the decrease in subjective anxiety levels, brain activity results suggest there was still a fear response in the brain.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Chemistry, Analytical
Farzana A. Mannan, Lilla A. Porffy, Dan W. Joyce, Sukhwinder S. Shergill, Oya Celiktutan
Summary: Cognitive impairment has a severe impact on safety and daily task performance. Virtual Reality (VR) systems are being used to recognize, diagnose and treat cognitive impairment. In this study, a novel VR-based measure of cognitive performance is described and shown to correlate with clinically-validated measures. The most important feature extracted from participants' behavior in the VR environment is found to be hesitation score.
Article
Clinical Neurology
Mitsuhiro Sado, Akihiro Koreki, Akira Ninomiya, Chika Kurata, Dai Mitsuda, Yasunori Sato, Toshiaki Kikuchi, Daisuke Fujisawa, Yutaka Ono, Masaru Mimura, Atsuo Nakagawa
Summary: This study compared the cost-effectiveness of augmented CBT adjunctive to treatment as usual (TAU) and TAU alone for pharmacotherapy-resistant depression at secondary mental health care settings. The results showed that augmented CBT was not cost-effective for all samples excluding mild depression, but appeared to be cost-effective for patients currently manifesting moderate/severe symptoms.
PSYCHIATRY AND CLINICAL NEUROSCIENCES
(2021)
Article
Business
Sandra Maria Correia Loureiro, Joao Guerreiro, Arnold Japutra
Summary: This study aims to understand how virtual reality influences consumer behavior by considering escapism as stimuli and examining the role of calm versus upbeat music tempo in the background. Through an experimental study and a conceptual framework, it was found that escapism stimulates consumers' cognitive and affective state, increasing pleasure and affecting their intentions. The link between presence and behavioral intention is stronger with calm music in the background, while the link between arousal and pleasure is stronger with upbeat music.
JOURNAL OF BUSINESS RESEARCH
(2021)
Article
Audiology & Speech-Language Pathology
Niraj Patel, Alicja N. Malicka, Siobhan McGinnity, Richard B. Anderson, Antonio G. Paolini, Paul Crosland
Summary: The study aimed to evaluate the economic effectiveness of different modalities of cognitive behavioral therapy (CBT) for subjective tinnitus in Australia. The results showed that CBT was cost-effective compared with no treatment, regardless of the treatment modality. Group CBT had the lowest cost per responder and per quality-adjusted life-year (QALY), while internet CBT had comparable economic outcomes. These findings suggest that group CBT and internet CBT should be more widely adopted in clinical practice for the treatment of subjective tinnitus.
Article
Clinical Neurology
Michael Darden, Colin A. Espie, Jenna R. Carl, Alasdair L. Henry, Jennifer C. Kanady, Andrew D. Krystal, Christopher B. Miller
Summary: The study found that fully automated digital cognitive behavioral therapy (CBT) is the most cost-effective treatment for insomnia in the United States, followed by group CBT, pharmacotherapy, and individual CBT. Utilizing automated digital CBT to treat insomnia at a population scale is financially prudent and beneficial from a societal perspective.
Article
Psychology, Clinical
Martin Lepage, Christopher R. Bowie, Tina Montreuil, Larry Baer, Olivier Percie du Sert, Tania Lecomte, Ridha Joober, Amal Abdel-Baki, G. Eric Jarvis, Howard C. Margolese, Luigi De Benedictis, Norbert Schmitz, Ashok K. Malla
Summary: A randomized controlled trial tested the efficacy of a group cognitive-behavioral therapy intervention for social anxiety in youth who experienced the first episode of psychosis. The results showed that both interventions led to a reduction in social anxiety, but the CBT-SA intervention had a positive effect on negative symptoms, functioning, and recovery.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
David van den Berg, Eva Tolmeijer, Alyssa Jongeneel, Anton B. P. Staring, Eline Palstra, Mark van der Gaag, Amy Hardy
Summary: The study examines the relationship between trauma and voice-hearing in people with psychosis. The findings suggest that trauma plays a significant role in shaping the content and psychological impact of voices. However, more research is needed to better understand these mechanisms.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Priscilla P. Oomen, Marieke J. H. Begemann, Bodyl A. Brand, Lieuwe de Haan, Wim Veling, Sanne Koops, Jim van Os, Filip Smit, P. Roberto Bakker, Nico van Beveren, Nynke Boonstra, Sinan Guloksuz, Martijn Kikkert, Joran Lokkerbol, Machteld Marcelis, Bram-Sieben Rosema, Franciska de Beer, Shiral S. Gangadin, Chris N. W. Geraets, Erna van't Hag, Yudith Haveman, Inge van der Heijden, Alban E. Voppel, Elske Willemse, Therese van Amelsvoort, Maarten Bak, Albert Batalla, Agaath Been, Marinte van den Bosch, Truus van den Brink, Gunnar Faber, Koen P. Grootens, Martin de Jonge, Rikus Knegtering, Jorg Kurkamp, Amrita Mahabir, Gerdina H. M. Pijnenborg, Tonnie Staring, Natalie Veen, Selene Veerman, Sybren Wiersma, Ellen Graveland, Joelle Hoornaar, Iris E. C. Sommer
Summary: This study identified three distinct cognitive subgroups in first-episode psychosis (FEP) and found that patients with severely impaired cognition had more severe clinical symptoms and lower general functioning compared to patients with preserved cognition. However, there were no significant differences in self-reported functional outcomes. Early identification of cognitive profiles can offer valuable information about clinical outcomes.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Marieke W. H. van den Heuvel, Denise H. M. Bodden, Filip Smit, Yvonne Stikkelbroek, John R. Weisz, Mirjam Moerbeek, Rutger C. M. E. Engels
Summary: This study investigated the relative effectiveness of dismantled Cognitive Behavioral Therapy (CBT) modules and found that one module of three sessions may not be sufficient to reduce depressive symptoms. The sequencing of the modules did not significantly influence outcomes.
JOURNAL OF CLINICAL CHILD AND ADOLESCENT PSYCHOLOGY
(2023)
Article
Anthropology
Madelien H. van de Beek, Erwin Landman, Wim Veling, Robert A. Schoevers, Lian van der Krieke
Summary: Migrants and their offspring are more prone to mental disorders, and the social factors play a significant role in their mental health. Young Moroccan-Dutch people feel isolated and discriminated against in their social environment. They explain mental health problems using religious and medical explanations.
TRANSCULTURAL PSYCHIATRY
(2023)
Article
Psychiatry
Stefania Tognin, Ana Catalan, Matthew J. Kempton, Barnaby Nelson, Patrick McGorry, Anita Riecher-Rossler, Rodrigo Bressan, Neus Barrantes-Vidal, Marie-Odile Krebs, Merete Nordentoft, Stephan Ruhrmann, Gabriele Sachs, Bart P. F. Rutten, Jim van Os, Lieuwe de Haan, Mark van der Gaag, Philip R. McGuire, Lucia Valmaggia
Summary: Research shows that adverse childhood experiences (ACE) can impact educational achievements in individuals at clinical high risk of psychosis (CHR). Specifically, CHR individuals with ACE had lower education levels, employment rates, and estimated IQ compared to healthy controls. Early intervention programs for psychosis should integrate interventions to support the educational and vocational recovery of young CHR individuals, and public health and social interventions to prevent or reduce the impact of ACE are recommended.
EUROPEAN PSYCHIATRY
(2023)
Article
Psychiatry
S. A. Nijman, G. H. M. Pijnenborg, R. R. Vermeer, C. E. R. Zandee, D. C. Zandstra, D. van der Vorm, A. C. de Wit-de Visser, I. A. Meins, C. N. W. Geraets, W. Veling
Summary: This study investigated the effectiveness of a virtual reality social cognition training (VR-SCT) called DiSCoVR. The results showed that DiSCoVR was not effective, possibly due to inadequate simulation of emotional expressions in the virtual reality environment. These findings suggest that current SCT protocols may be relatively unsuitable for improving social functioning.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Medicine, Research & Experimental
U. N. Jeppesen, A. S. Due, L. Mariegaard, A. Pinkham, M. Vos, W. Veling, M. Nordentoft, L. B. Glenthoj
Summary: Unfortunately, we had to update our study protocol due to a significant change in the study design. The approval to change the primary outcome was rejected because the trial had already started. Therefore, we had to keep the Green Paranoid Thought Scale (GPTS) part B as our primary outcome and GPTS part A as a secondary outcome. The change did not affect participation or informed consent.
Article
Psychology, Clinical
Simone R. Burger, Amy Hardy, Tineke van der Linden, Catherine van Zelst, Paul A. J. de Bont, Berber van der Vleugel, Anton B. P. Staring, Carlijn de Roos, Ad de Jongh, Machteld Marcelis, Agnes van Minnen, Mark van der Gaag, David P. G. van den Berg
Summary: This study investigated symptom exacerbation during trauma-focused therapy in people with PTSD and psychosis. The results showed that symptom exacerbation was common but not associated with poor treatment outcomes or treatment drop-out. Therefore, symptom exacerbation should not be a barrier to implementing trauma-focused therapy in this population.
JOURNAL OF TRAUMATIC STRESS
(2023)
Article
Immunology
Valeria Mondelli, Graham Blackman, Matthew J. Kempton, Thomas A. Pollak, Conrad Iyegbe, Lucia R. Valmaggia, Paul Amminger, Neus Barrantes-Vidal, Rodrigo Bressan, Mark van der Gaag, Lieuwe de Haan, Marie-Odile Krebs, Merete Nordentoft, Stephan Ruhrmann, Anita Riecher-Roessler, Bart P. F. Rutten, Gabriele Sachs, Nikolaos Koutsouleris, Philip McGuire
Summary: Individuals at clinical high risk for psychosis show altered cytokine levels, with increased VEGF and IL-10/IL-6 ratio associated with the transition to psychosis. These findings suggest that peripheral immune markers play a role in the onset of psychosis.
BRAIN BEHAVIOR AND IMMUNITY
(2023)
Article
Psychology, Social
Saskia A. Nijman, Wim Veling, Marieke E. Timmerman, Gerdina H. M. Pijnenborg
Summary: Meta-analyses have shown that social cognition training (SCT) has significant effects on emotion recognition of individuals with psychotic disorders. Virtual reality (VR) holds promise as a tool for delivering SCT. However, it is currently unknown how improvements in emotion recognition during (VR-)SCT develop, the factors influencing improvement, and the relationship between VR improvements and improvements in real life.
CYBERPSYCHOLOGY BEHAVIOR AND SOCIAL NETWORKING
(2023)
Review
Psychology, Clinical
Simon Riches, Lawson Taylor, Priyanga Jeyarajaguru, Wim Veling, Lucia Valmaggia
Summary: This systematic review evaluates the feasibility, acceptability, and effectiveness of immersive technologies in promoting workplace wellbeing. The findings show that immersive VR environments can provide relaxation and stress reduction experiences that are helpful for workplaces, but more long-term data and controlled trials are needed to support the conclusions.
JOURNAL OF MENTAL HEALTH
(2023)
Article
Economics
B. F. M. Wijnen, M. Ten Have, R. de Graaf, H. J. van der Hoek, J. Lokkerbol, Filip Smit
Summary: Currently, there is a lack of up-to-date estimates on the economic burden caused by mental disorders. This study used data from a national psychiatric-epidemiological cohort study to provide reliable and relevant cost estimates regarding healthcare costs, productivity losses, and patient and family costs associated with mental disorders.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Psychiatry
Jojanneke Bruins, Stijn Crutzen, Wim Veling, Stynke Castelein
Summary: Research found that there are facilitating and impeding factors in quitting cannabis use for patients with severe mental illness. Seeking distraction, social contacts, avoiding temptation, and support from professionals were facilitating factors, while withdrawal symptoms, user environment, stress, and routine were impeding factors. Advice to other patients included just do it, seek support, quit cold turkey, and acknowledge the problem of cannabis use. Advice to mental health professionals was to discuss cannabis use from the start of treatment.
Article
Psychology, Clinical
Jelle Sjoerd Vogel, Jojanneke Bruins, Marte Swart, Edith Liemburg, Mark van der Gaag, Stynke Castelein
Summary: This randomized controlled trial investigated the effects of an eating club intervention on personal and societal recovery in patients with a psychotic disorder. The intervention did not show any significant effects on personal recovery or secondary outcomes, but higher attendance was associated with better social functioning scores.
JOURNAL OF BEHAVIOR THERAPY AND EXPERIMENTAL PSYCHIATRY
(2023)