Journal
CHEMICAL COMMUNICATIONS
Volume 52, Issue 11, Pages 2307-2310Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc08350h
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Funding
- NSF [CHE-1112091]
- NIH [R01GM097571]
- NSF
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A naphthalimide based fluorescent sensor displaying a significant increase in emission upon binding CB[7] with notable pH stability was developed and utilized in a surface-bound displacement assay for the rapid detection of CB[7] encapsulation of therapeutically relevant drug classes. Previously unknown binders with moderate to strong affinities were discovered.
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