4.7 Article

Combined covalent and noncovalent carboxylation of carbon nanotubes for sensitivity enhancement of clinical immunosensors

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 88, Pages 13039-13042

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc07022a

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Funding

  1. National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health [R15DK103386]

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We report here for the first time with quantitative details that the combination of pi-pi stacking of pyrenecarboxylic acid with chemically carboxylated multiwalled carbon nanotubes (MWNT-COOH) offers superior sensitivity compared to MWNT-COOH alone for serum insulin measurements and that this combination is broadly applicable for biosensors, drug delivery, and catalytic systems.

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