Genome-wide meta-analysis identifies novel loci associated with age-related macular degeneration

Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration

(2019) Rinki Ratnapriya et al.   NATURE GENETICS

Identification of common genetic risk variants for autism spectrum disorder

(2019) Jakob Grove et al.   NATURE GENETICS

Pax6 regulation ofSox9in the retinal pigmented epithelium controls its timely differentiation and choroid vasculature development

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ACSL5 genotype influence on fatty acid metabolism: a cellular, tissue, and whole-body study

(2018) Abishankari Rajkumar et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma

(2018) Stuart MacGregor et al.   NATURE GENETICS

Multi-trait analysis of genome-wide association summary statistics using MTAG

(2018) Patrick Turley et al.   NATURE GENETICS

Investigating the modulation of genetic effects on late AMD by age and sex: Lessons learned and two additional loci

(2018) Thomas W. Winkler et al.   PLoS One

Age-related macular degeneration

(2018) Paul Mitchell et al.   LANCET

Genome-wide association analyses identify 139 loci associated with macular thickness in the UK Biobank cohort

(2018) X Raymond Gao et al.   HUMAN MOLECULAR GENETICS

Combined VEGF and PDGF inhibition for neovascular AMD: anti-angiogenic properties of axitinib on human endothelial cells and pericytes in vitro

(2017) Jakob Siedlecki et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Genome-wide analyses identify common variants associated with macular telangiectasia type 2

(2017) Thomas S Scerri et al.   NATURE GENETICS

Dual Antagonism of PDGF and VEGF in Neovascular Age-Related Macular Degeneration

(2017) Glenn J. Jaffe et al.   OPHTHALMOLOGY

Mendelian Randomization Implicates High-Density Lipoprotein Cholesterol–Associated Mechanisms in Etiology of Age-Related Macular Degeneration

(2017) Stephen Burgess et al.   OPHTHALMOLOGY

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

(2016) Zhihong Zhu et al.   NATURE GENETICS

Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error

(2016) Qiao Fan et al.   Nature Communications

Amyloidosis in Retinal Neurodegenerative Diseases

(2016) Ambra Masuzzo et al.   Frontiers in Neurology

Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

(2015) Mark N. Kvale et al.   GENETICS

Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

(2015) Yambazi Banda et al.   GENETICS

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

(2015) Lars G Fritsche et al.   NATURE GENETICS

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

(2015) Mark N. Kvale et al.   GENETICS

Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

(2015) Yambazi Banda et al.   GENETICS

Disruption ofVisc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype

(2014) Peter L. Oliver et al.   CEREBRAL CORTEX

Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis

(2014) Wan Ling Wong et al.   Lancet Global Health

Exon-level expression profiling of ocular tissues

(2013) Alex H. Wagner et al.   EXPERIMENTAL EYE RESEARCH

Seven new loci associated with age-related macular degeneration

(2013) Lars G Fritsche et al.   NATURE GENETICS

Quantitative Classification of Eyes with and without Intermediate Age-related Macular Degeneration Using Optical Coherence Tomography

(2013) Sina Farsiu et al.   OPHTHALMOLOGY

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

Role of the retinal vascular endothelial cell in ocular disease

(2012) Arpita S. Bharadwaj et al.   PROGRESS IN RETINAL AND EYE RESEARCH

pROC: an open-source package for R and S+ to analyze and compare ROC curves

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METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

NF-κB signaling as a putative target for ω-3 metabolites in the prevention of age-related macular degeneration (AMD)

(2009) Kai Kaarniranta et al.   EXPERIMENTAL GERONTOLOGY

Retinal Vascular Caliber: Systemic, Environmental, and Genetic Associations

(2009) Cong Sun et al.   SURVEY OF OPHTHALMOLOGY

Retinal Vascular Caliber and Age-related Macular Degeneration: The Singapore Malay Eye Study

(2008) V. Swetha E. Jeganathan et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Complement evasion by human pathogens

(2008) John D. Lambris et al.   NATURE REVIEWS MICROBIOLOGY