Journal
CHEMICAL COMMUNICATIONS
Volume 52, Issue 5, Pages 896-899Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc07054f
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Funding
- Natural Science Foundation of China [21174100, 91326202, U1532111]
- Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
- Qing-Lan Project of Jiangsu Province
- Jiangsu Key Laboratory of Radiation Medicine and Protection
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We demonstrate here a strategy for enhanced antibacterial activity against microbial strains by the assembly of antimicrobial peptides with a temperature-responsive polymeric carrier. The assembly complex was less toxic to human cells and more stable to enzymatic cleavage. This work may provide a promising drug delivery system for antimicrobial peptides.
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