4.7 Article

A rapid-response fluorescent probe for the sensitive and selective detection of human albumin in plasma and cell culture supernatants

Journal

CHEMICAL COMMUNICATIONS
Volume 52, Issue 36, Pages 6064-6067

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc00119j

Keywords

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Funding

  1. National S&T Major Projects of China [2012ZX09501001, 2012ZX09506001]
  2. NSF of China [81473181, 81302793, 81573501, 21421005, 21572029]
  3. State Key Laboratory of Fine Chemicals [KF1504, KF1408]

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A rapid-response fluorescent probe ACDM was developed for the selective and sensitive detection of human albumin (HA) via binding onto a non-drug binding site. ACDM was successfully used to detect trace HA in various biological samples including diluted plasma and cell culture supernatants.

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