Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells

Investigation of Specific Binding Proteins to Photoaffinity Linkers for Efficient Deconvolution of Target Protein

(2015) Jongmin Park et al.   ACS Chemical Biology

A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells

(2015) Micah J. Niphakis et al.   CELL

Photoaffinity labeling in target- and binding-site identification

(2015) Ewan Smith et al.   Future Medicinal Chemistry

Multivalent Photoaffinity Probe for Labeling Small Molecule Binding Proteins

(2014) Gang Li et al.   BIOCONJUGATE CHEMISTRY

“Minimalist” Cyclopropene-Containing Photo-Cross-Linkers Suitable for Live-Cell Imaging and Affinity-Based Protein Labeling

(2014) Zhengqiu Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mapping the Protein Interaction Landscape for Fully Functionalized Small-Molecule Probes in Human Cells

(2014) Tohru Kambe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

(2013) Zhengqiu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photoaffinity Labeling of Small-Molecule-Binding Proteins by DNA-Templated Chemistry

(2013) Gang Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Target identification of biologically active small molecules via in situ methods

(2013) Ying Su et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Target identification and mechanism of action in chemical biology and drug discovery

(2013) Monica Schenone et al.   Nature Chemical Biology

Discovery and Target Identification of an Antiproliferative Agent in Live Cells Using Fluorescence Difference in Two-Dimensional Gel Electrophoresis

(2012) Jongmin Park et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cell-Based Proteome Profiling of Potential Dasatinib Targets by Use of Affinity-Based Probes

(2012) Haibin Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fully Functionalized Small-Molecule Probes for Integrated Phenotypic Screening and Target Identification

(2012) Justin S. Cisar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From noncovalent to covalent bonds: a paradigm shift in target protein identification

(2012) Jongmin Park et al.   Molecular BioSystems

The Binding of Fluorophores to Proteins Depends on the Cellular Environment

(2011) Yun Kyung Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Marine Natural Product Aurilide Activates the OPA1-Mediated Apoptosis by Binding to Prohibitin

(2011) Shin-ichi Sato et al.   CHEMISTRY & BIOLOGY

Biochemical Target Isolation for Novices: Affinity-Based Strategies

(2010) Shin-ichi Sato et al.   CHEMISTRY & BIOLOGY

Activity-Based Proteome Profiling of Potential Cellular Targets of Orlistat − An FDA-Approved Drug with Anti-Tumor Activities

(2009) Peng-Yu Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Target profiling of small molecules by chemical proteomics

(2009) Uwe Rix et al.   Nature Chemical Biology

Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences

(2008) Huan-Xiang Zhou et al.   Annual Review of Biophysics

Identification of the cellular targets of bioactive small organic molecules using affinity reagents

(2008) Benjamin J. Leslie et al.   CHEMICAL SOCIETY REVIEWS