Journal
CHEMICAL COMMUNICATIONS
Volume 52, Issue 11, Pages 2304-2306Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc07752d
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Funding
- National Sciences Foundation of China [21402188]
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Tetrahydroquinolines (THQs) with an all-carbon quaternary stereocenter were effectively obtained via the in situ formation of aza-ortho-xylylene (AOX) with easily accessible 1,2-dihydroquinolines as precursors. The reaction was rationalizedwith chiral phosporic acid to afford chiral THQs with high yield and excellent enantioselectivity.
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