Laboratory Diagnosis of COVID-19: Current Issues and Challenges

Molecular Diagnosis of a Novel Coronavirus (2019-nCoV) Causing an Outbreak of Pneumonia

(2020) Daniel K W Chu et al.   CLINICAL CHEMISTRY

A Well Infant with Coronavirus Disease 2019 (COVID-19) with High Viral Load

(2020) Kai-qian Kam et al.   CLINICAL INFECTIOUS DISEASES

Consistent Detection of 2019 Novel Coronavirus in Saliva

(2020) Kelvin Kai-Wang To et al.   CLINICAL INFECTIOUS DISEASES

Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR

(2020) Victor M Corman et al.   Eurosurveillance

Escalating infection control response to the rapidly evolving epidemiology of the Coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in Hong Kong

(2020) Vincent C.C. Cheng et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Positive RT-PCR Test Results in Patients Recovered From COVID-19

(2020) Lan Lan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Coronavirus Infections—More Than Just the Common Cold

(2020) Catharine I. Paules et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore

(2020) Barnaby Edward Young et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

COVID-19—New Insights on a Rapidly Changing Epidemic

(2020) Carlos del Rio et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Improved molecular diagnosis of COVID-19 by the novel, highly sensitive and specific COVID-19-RdRp/Hel real-time reverse transcription-polymerase chain reaction assay validated in vitro and with clinical specimens

(2020) Jasper Fuk-Woo Chan et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Development and Clinical Application of A Rapid IgM‐IgG Combined Antibody Test for SARS‐CoV‐2 Infection Diagnosis

(2020) Zhengtu Li et al.   JOURNAL OF MEDICAL VIROLOGY

Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2

(2020) Zhixin Liu et al.   JOURNAL OF MEDICAL VIROLOGY

Outbreak of pneumonia of unknown etiology in Wuhan, China: The mystery and the miracle

(2020) Hongzhou Lu et al.   JOURNAL OF MEDICAL VIROLOGY

Secondary attack rate and superspreading events for SARS-CoV-2

(2020) Yang Liu et al.   LANCET

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

(2020) Jasper Fuk-Woo Chan et al.   LANCET

Viral load of SARS-CoV-2 in clinical samples

(2020) Yang Pan et al.   LANCET INFECTIOUS DISEASES

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

A Novel Coronavirus Emerging in China — Key Questions for Impact Assessment

(2020) Vincent J. Munster et al.   NEW ENGLAND JOURNAL OF MEDICINE

Covid-19 — Navigating the Uncharted

(2020) Anthony S. Fauci et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

(2020) Lirong Zou et al.   NEW ENGLAND JOURNAL OF MEDICINE

First Case of 2019 Novel Coronavirus in the United States

(2020) Michelle L. Holshue et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany

(2020) Camilla Rothe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia

(2020) Qun Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

(2020) Renhong Yan et al.   SCIENCE

Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes

(2020) Wei Zhang et al.   Emerging Microbes & Infections

RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak

(2020) Liangjun Chen et al.   Emerging Microbes & Infections

Enteric involvement of coronaviruses: is faecal–oral transmission of SARS-CoV-2 possible?

(2020) Charleen Yeo et al.   Lancet Gastroenterology & Hepatology

Identification of a novel coronavirus causing severe pneumonia in human

(2020) Li-Li Ren et al.   CHINESE MEDICAL JOURNAL

Quantitative Detection and Viral Load Analysis of SARS-CoV-2 in Infected Patients

(2020) Fengting Yu et al.   CLINICAL INFECTIOUS DISEASES

Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19)

(2020) Li Guo et al.   CLINICAL INFECTIOUS DISEASES

Detection of SARS-CoV-2 in Different Types of Clinical Specimens

(2020) Wenling Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Virological assessment of hospitalized patients with COVID-2019

(2020) Roman Wölfel et al.   NATURE

Viral dynamics in mild and severe cases of COVID-19

(2020) Yang Liu et al.   LANCET INFECTIOUS DISEASES

Profile of the Alere i Influenza A & B assay: a pioneering molecular point-of-care test

(2018) Hongmei Wang et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Origin and evolution of pathogenic coronaviruses

(2018) Jie Cui et al.   NATURE REVIEWS MICROBIOLOGY

Parallel Validation of Three Molecular Devices for Simultaneous Detection and Identification of Influenza A and B and Respiratory Syncytial Viruses

(2017) Lifen Ling et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The effect of a non-denaturing detergent and a guanidinium-based inactivation agent on the viability of Ebola virus in mock clinical serum samples

(2017) J.E. Burton et al.   JOURNAL OF VIROLOGICAL METHODS

Additional molecular testing of saliva specimens improves the detection of respiratory viruses

(2017) Kelvin KW To et al.   Emerging Microbes & Infections

A highly specific rapid antigen detection assay for on-site diagnosis of MERS

(2016) Yixin Chen et al.   JOURNAL OF INFECTION

Inactivation and safety testing of Middle East Respiratory Syndrome Coronavirus

(2015) Mia Kumar et al.   JOURNAL OF VIROLOGICAL METHODS

Evaluation of Alere i Influenza A&B for Rapid Detection of Influenza Viruses A and B

(2014) Shuping Nie et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Middle East Respiratory Syndrome Coronavirus Quasispecies That Include Homologues of Human Isolates Revealed through Whole-Genome Analysis and Virus Cultured from Dromedary Camels in Saudi Arabia

(2014) T. Briese et al.   mBio

Evaluation of Swabs, Transport Media, and Specimen Transport Conditions for Optimal Detection of Viruses by PCR

(2011) J. Druce et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Comparison of Nasopharyngeal and Oropharyngeal Swabs for the Diagnosis of Eight Respiratory Viruses by Real-Time Reverse Transcription-PCR Assays

(2011) Curi Kim et al.   PLoS One

Differentiation between Human Coronaviruses NL63 and 229E Using a Novel Double-Antibody Sandwich Enzyme-Linked Immunosorbent Assay Based on Specific Monoclonal Antibodies

(2010) Patricia Sastre et al.   Clinical and Vaccine Immunology

Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus

(2009) C.M. Chan et al.   JOURNAL OF CLINICAL VIROLOGY