Posttreatment Lyme disease syndromes: distinct pathogenesis caused by maladaptive host responses

A Review of Antibiotic-Tolerant Persisters and Their Relevance to Posttreatment Lyme Disease Symptoms

(2020) Phillip J. Baker   AMERICAN JOURNAL OF MEDICINE

Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis

(2019) Brandon L. Jutras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Robust interferon signature and suppressed tissue repair gene expression in synovial tissue from patients with post-infectious, Borrelia burgdorferi -induced Lyme arthritis

(2018) Robert B. Lochhead et al.   CELLULAR MICROBIOLOGY

Interferon‐gamma production in Lyme arthritis synovial tissue promotes differentiation of fibroblast‐like synoviocytes into immune effector cells

(2018) Robert B. Lochhead et al.   CELLULAR MICROBIOLOGY

MicroRNA Expression Shows Inflammatory Dysregulation and Tumor-Like Proliferative Responses in Joints of Patients With Postinfectious Lyme Arthritis

(2017) Robert B. Lochhead et al.   Arthritis & Rheumatology

CCL19 as a Chemokine Risk Factor for Posttreatment Lyme Disease Syndrome: a Prospective Clinical Cohort Study

(2016) John N. Aucott et al.   Clinical and Vaccine Immunology

Matrix metalloproteinase-10 is a target of T and B cell responses that correlate with synovial pathology in patients with antibiotic-refractory Lyme arthritis

(2016) Jameson T. Crowley et al.   JOURNAL OF AUTOIMMUNITY

Randomized Trial of Longer-Term Therapy for Symptoms Attributed to Lyme Disease

(2016) Anneleen Berende et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autoimmune Arthritides, Rheumatoid Arthritis, Psoriatic Arthritis, or Peripheral Spondyloarthritis Following Lyme Disease

(2016) Sheila L. Arvikar et al.   Arthritis & Rheumatology

Borrelia burgdorferi, the Causative Agent of Lyme Disease, Forms Drug-Tolerant Persister Cells

(2015) Bijaya Sharma et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Posttreatment Lyme Disease Syndrome

(2015) John N. Aucott   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Drug Combinations against Borrelia burgdorferi Persisters In Vitro: Eradication Achieved by Using Daptomycin, Cefoperazone and Doxycycline

(2015) Jie Feng et al.   PLoS One

Xenodiagnosis to Detect Borrelia burgdorferi Infection: A First-in-Human Study

(2014) Adriana Marques et al.   CLINICAL INFECTIOUS DISEASES

Dysregulation of CD4+CD25highT Cells in the Synovial Fluid of Patients With Antibiotic-Refractory Lyme Arthritis

(2013) Nalini K. Vudattu et al.   ARTHRITIS AND RHEUMATISM

Elevated Levels of IL-23 in a Subset of Patients With Post-Lyme Disease Symptoms Following Erythema Migrans

(2013) K. Strle et al.   CLINICAL INFECTIOUS DISEASES

Post-Treatment Lyme Syndrome and Central Sensitization

(2013) Shweta Batheja et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

Association of a Toll-like receptor 1 polymorphism with heightened Th1 inflammatory responses and antibiotic-refractory Lyme arthritis

(2012) Klemen Strle et al.   ARTHRITIS AND RHEUMATISM

Persistence of Borrelia burgdorferi in Rhesus Macaques following Antibiotic Treatment of Disseminated Infection

(2012) Monica E. Embers et al.   PLoS One

Burden and viability of Borrelia burgdorferi in skin and joints of patients with erythema migrans or lyme arthritis

(2011) Xin Li et al.   ARTHRITIS AND RHEUMATISM

HLA–DR alleles determine responsiveness toBorrelia burgdorferiantigens in a mouse model of self-perpetuating arthritis

(2009) Bettina Panagiota Iliopoulou et al.   ARTHRITIS AND RHEUMATISM