Dysfunctional polycomb transcriptional repression contributes to lamin A/C–dependent muscular dystrophy

The K219T-Lamin mutation induces conduction defects through epigenetic inhibition of SCN5A in human cardiac laminopathy

(2019) Nicolò Salvarani et al.   Nature Communications

The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes

(2018) Tess Tsai-Hsiu Lu et al.   Cell Metabolism

Lamins Organize the Global Three-Dimensional Genome from the Nuclear Periphery

(2018) Xiaobin Zheng et al.   MOLECULAR CELL

Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells

(2018) Milica Tosic et al.   Nature Communications

Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways

(2018) Takahiro Ito et al.   Cell Reports

Laminopathy-causing lamin A mutations reconfigure lamina-associated domains and local spatial chromatin conformation

(2018) Nolwenn Briand et al.   Nucleus

Laminopathy-causing lamin A mutations reconfigure lamina-associated domains and local spatial chromatin conformation

(2018) Nolwenn Briand et al.   Nucleus

A lipodystrophy-causing lamin A mutant alters conformation and epigenetic regulation of the anti-adipogenic MIR335 locus

(2017) Anja Oldenburg et al.   JOURNAL OF CELL BIOLOGY

Protein sequestration at the nuclear periphery as a potential regulatory mechanism in premature aging

(2017) Leonid Serebryannyy et al.   JOURNAL OF CELL BIOLOGY

Polycomb Repressive Complex 1 Generates Discrete Compacted Domains that Change during Differentiation

(2017) Sharmistha Kundu et al.   MOLECULAR CELL

The molecular architecture of lamins in somatic cells

(2017) Yagmur Turgay et al.   NATURE

Gene bivalency at Polycomb domains regulates cranial neural crest positional identity

(2017) Maryline Minoux et al.   SCIENCE

EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop

(2017) Wendy Béguelin et al.   Nature Communications

Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity

(2016) Fulvio Chiacchiera et al.   Cell Stem Cell

Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation

(2016) Verawan Boonsanay et al.   Cell Stem Cell

Cell reprogramming during regeneration in Drosophila : transgression of compartment boundaries

(2016) Ginés Morata et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Satellite Cells in Muscular Dystrophy – Lost in Polarity

(2016) Natasha C. Chang et al.   TRENDS IN MOLECULAR MEDICINE

Nucleoplasmic Lamin A/C and Polycomb group of proteins: An evolutionarily conserved interplay

(2016) F. Marullo et al.   Nucleus

Nucleoplasmic Lamin A/C and Polycomb group of proteins: An evolutionarily conserved interplay

(2016) F. Marullo et al.   Nucleus

Lamin A/C sustains PcG protein architecture, maintaining transcriptional repression at target genes

(2015) Elisa Cesarini et al.   JOURNAL OF CELL BIOLOGY

Structural organization of nuclear lamins A, C, B1, and B2 revealed by superresolution microscopy

(2015) Takeshi Shimi et al.   MOLECULAR BIOLOGY OF THE CELL

Geroconversion of aged muscle stem cells under regenerative pressure

(2014) Pedro Sousa-Victor et al.   CELL CYCLE

Geriatric muscle stem cells switch reversible quiescence into senescence

(2014) Pedro Sousa-Victor et al.   NATURE

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

(2014) Benjamin D Cosgrove et al.   NATURE MEDICINE

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

(2014) Jennifer D Bernet et al.   NATURE MEDICINE

Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome

(2014) David A. Orlando et al.   Cell Reports

LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

(2013) Irina Solovei et al.   CELL

Defective skeletal muscle growth in lamin A/C-deficient mice is rescued by loss of Lap2α

(2013) Tatiana V. Cohen et al.   HUMAN MOLECULAR GENETICS

Chromatin Modifications as Determinants of Muscle Stem Cell Quiescence and Chronological Aging

(2013) Ling Liu et al.   Cell Reports

Muscle development, regeneration and laminopathies: how lamins or lamina-associated proteins can contribute to muscle development, regeneration and disease

(2012) Magda Dubinska-Magiera et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ring1a/b polycomb proteins regulate the mesenchymal stem cell niche in continuously growing incisors

(2012) Puangwan Lapthanasupkul et al.   DEVELOPMENTAL BIOLOGY

The aged niche disrupts muscle stem cell quiescence

(2012) Joe V. Chakkalakal et al.   NATURE

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Polycomb-Dependent Regulatory Contacts between Distant Hox Loci in Drosophila

(2011) Frédéric Bantignies et al.   CELL

Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells

(2011) A. H. Juan et al.   GENES & DEVELOPMENT

Lamin A/C deficiency is associated with fat infiltration of muscle and bone

(2011) Jessica Tong et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Lamin A and lamin C form homodimers and coexist in higher complex forms both in the nucleoplasmic fraction and in the lamina of cultured human cells

(2011) Thorsten Kolb et al.   Nucleus

Impaired nuclear functions lead to increased senescence and inefficient differentiation in human myoblasts with a dominant p.R545C mutation in the LMNA gene

(2009) Sebastian Kandert et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Does satellite cell dysfunction contribute to disease progression in Emery–Dreifuss muscular dystrophy?

(2008) Viola F. Gnocchi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS