Synthesis and evaluation of novel amonafide-polyamine conjugates as anticancer agents

Recent Developments in the Synthesis and Applications of Anticancer Amonafide Derivatives. A Mini Review

(2015) Gary Gellerman   Letters in Drug Design & Discovery

UNBS5162, a Novel Naphthalimide That Decreases CXCL Chemokine Expression in Experimental Prostate Cancers

(2015) Tatjana Mijatovic et al.   NEOPLASIA

Naphthalimides Induce G2 Arrest Through the ATM-Activated Chk2-Executed Pathway in HCT116 Cells

(2015) Hong Zhu et al.   NEOPLASIA

Activity of the polyamine-vectorized anti-cancer drug F14512 against pediatric glioma and neuroblastoma cell lines.

(2014) Pierre Leblond et al.   INVESTIGATIONAL NEW DRUGS

Recent advances in the development of 1,8-naphthalimide based DNA targeting binders, anticancer and fluorescent cellular imaging agents

(2013) Swagata Banerjee et al.   CHEMICAL SOCIETY REVIEWS

Novel naphthalimide polyamine derivatives as potential antitumor agents

(2013) Robert Seliga et al.   MOLECULAR BIOLOGY REPORTS

Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion

(2013) Neel Sengupta et al.   Molecular Cancer

Nonhematotoxic Naphthalene Diimide Modified by Polyamine: Synthesis and Biological Evaluation

(2012) Yuxia Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands

(2011) Antonella Peduto et al.   BIOORGANIC & MEDICINAL CHEMISTRY

NPC-16, a novel naphthalimide–polyamine conjugate, induced apoptosis and autophagy in human hepatoma HepG2 cells and Bel-7402 cells

(2010) Song-qiang Xie et al.   APOPTOSIS

Synthesis and anticancer activities of 6-amino amonafide derivatives

(2009) John T. Norton et al.   ANTI-CANCER DRUGS

Naphthalimides and Azonafides as Promising Anti-Cancer Agents

(2009) Laurent Ingrassia et al.   CURRENT MEDICINAL CHEMISTRY

Preclinical activity of F14512, designed to target tumors expressing an active polyamine transport system

(2009) Anna Kruczynski et al.   INVESTIGATIONAL NEW DRUGS

F14512, a Potent Antitumor Agent Targeting Topoisomerase II Vectored into Cancer Cells via the Polyamine Transport System

(2008) J.-M. Barret et al.   CANCER RESEARCH